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Immunology

D-Index
89
Citations
22927
World Ranking
1133
National Ranking
600

Medicine

D-Index
89
Citations
22929
World Ranking
12862
National Ranking
6577

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors
  • 2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Prakash S. Nagarkatti is affiliated with the University of South Carolina in the United States. Their research spans multiple fields with a focus on immunology, microbiology, medicine, and biochemistry, genetics, and molecular biology. The primary subfields of study include immunology, molecular biology, pharmacology, epidemiology, and pulmonary and respiratory medicine.

Their scholarly output covers a range of topics in biomedical research, including immune cell function and interaction, gut microbiota and health, immune cells in cancer, immune response and inflammation, IL-33, ST2, and ILC pathways, tryptophan and brain disorders, as well as cannabis and cannabinoid research.

Frequent collaborators in their research include Mitzi Nagarkatti, Kiesha Wilson, Philip Brandon Busbee, Xiaoming Yang, and Narendra P. Singh. These partnerships reflect strong collaborative efforts in advancing their scientific inquiries.

Prakash S. Nagarkatti has published extensively in respected scientific venues, with a significant number of publications appearing in "The Journal of Immunology," followed by contributions to "Frontiers in Immunology," "International Journal of Molecular Sciences," "Frontiers in Pharmacology," and "bioRxiv (Cold Spring Harbor Laboratory)."

Notable recent papers authored by or involving Nagarkatti include:

  • Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner (2020, JCI Insight)
  • Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation (2020, Theranostics)
  • Autophagy Inhibition Enables Nrf2 to Exaggerate the Progression of Diabetic Cardiomyopathy in Mice (2020, Diabetes)
  • Alterations in the Gut Microbiome and Suppression of Histone Deacetylases by Resveratrol Are Associated with Attenuation of Colonic Inflammation and Protection Against Colorectal Cancer (2020, Journal of Clinical Medicine)
  • Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis (2020, Journal of Neuroinflammation)

Among their recognitions, Nagarkatti has been named Fellow of the National Academy of Inventors in 2018 and Fellow of the American Association for the Advancement of Science (AAAS) in 2011.

Best Publications

  • Cannabinoids as novel anti-inflammatory drugs

    Prakash Nagarkatti;Rupal Pandey;Sadiye Amcaoglu Rieder;Venkatesh L Hegde

  • Role of cytokines as a double-edged sword in sepsis.

    Hina Chaudhry;Juhua Zhou;Juhua Zhou;Yin Zhong;Mir Mustafa Ali

  • Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease

    Robert J McKallip;Catherine Lombard;Michael T Fisher;Billy R Martin

  • Chemokine and cytokine levels in inflammatory bowel disease patients

    Udai P. Singh;Narendra P. Singh;E. Angela Murphy;Robert L. Price

  • Deoxycholic Acid (DCA) Causes Ligand-independent Activation of Epidermal Growth Factor Receptor (EGFR) and FAS Receptor in Primary Hepatocytes: Inhibition of EGFR/Mitogen-activated Protein Kinase-Signaling Module Enhances DCA-induced Apoptosis

    Liang Qiao;Elaine Studer;Kevin Leach;Robert McKinstry

  • Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression

    Sadiye Amcaoglu Rieder;Ashok Chauhan;Ugra Singh;Mitzi Nagarkatti

  • Activation of aryl hydrocarbon receptor (AhR) leads to reciprocal epigenetic regulation of FoxP3 and IL-17 expression and amelioration of experimental colitis.

    Narendra P. Singh;Udai P. Singh;Balwan Singh;Robert L. Price

  • Δ-9-Tetrahydrocannabinol Enhances Breast Cancer Growth and Metastasis by Suppression of the Antitumor Immune Response

    Robert J. McKallip;Mitzi Nagarkatti;Prakash S. Nagarkatti

  • Endocannabinoids and immune regulation.

    Rupal Pandey;Khalida Mousawy;Mitzi Nagarkatti;Prakash Nagarkatti

  • Bryostatin Modulates Latent HIV-1 Infection via PKC and AMPK Signaling but Inhibits Acute Infection in a Receptor Independent Manner

    Rajeev Mehla;Shalmali Bivalkar-Mehla;Ruonan Zhang;Indhira Handy

  • Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.

    Robert J. McKallip;Wentao Jia;Jerome Schlomer;James W. Warren

  • Resveratrol Suppresses Colitis and Colon Cancer Associated with Colitis

    Xiangli Cui;Yu Jin;Anne B. Hofseth;Edsel Pena

  • Expression, Regulation and Function of MicroRNAs in Multiple Sclerosis

    Xinting Ma;Juhua Zhou;Yin Zhong;Linlin Jiang

  • Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor.

    Narendra P. Singh;Venkatesh L. Hegde;Lorne J. Hofseth;Mitzi Nagarkatti

  • Activation through Cannabinoid Receptors 1 and 2 on Dendritic Cells Triggers NF-κB-Dependent Apoptosis: Novel Role for Endogenous and Exogenous Cannabinoids in Immunoregulation

    Yoonkyung Do;Robert J. McKallip;Mitzi Nagarkatti;Prakash S. Nagarkatti

  • Use of natural AhR ligands as potential therapeutic modalities against inflammatory disorders.

    Philip B Busbee;Michael Rouse;Mitzi Nagarkatti;Prakash S Nagarkatti

  • A critical role of cardiac fibroblast-derived exosomes in activating renin angiotensin system in cardiomyocytes.

    Linmao Lyu;Hui Wang;Bin Li;Qingyun Qin

  • Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo.

    Robert J. McKallip;Catherine Lombard;Billy R. Martin;Mitzi Nagarkatti

  • Resveratrol (Trans-3,5,4′-trihydroxystilbene) Induces Silent Mating Type Information Regulation-1 and Down-Regulates Nuclear Transcription Factor-κB Activation to Abrogate Dextran Sulfate Sodium-Induced Colitis

    Udai P. Singh;Narendra P. Singh;Balwan Singh;Lorne J. Hofseth

  • Dysregulation in microRNA expression is associated with alterations in immune functions in combat veterans with post-traumatic stress disorder.

    Juhua Zhou;Prakash Nagarkatti;Yin Zhong;Jay P. Ginsberg

  • Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo.

    Arati B. Kamath;Huimin Xu;Prakash S. Nagarkatti;Mitzi Nagarkatti

Frequent Co-Authors

Mitzi Nagarkatti
Mitzi Nagarkatti University of South Carolina
Dennis D. Taub
Dennis D. Taub George Washington University
Anna Mae Diehl
Anna Mae Diehl Duke University
Bryan W. Brooks
Bryan W. Brooks Baylor University
James A. Carson
James A. Carson University of Tennessee Health Science Center
Xuejun Wang
Xuejun Wang University of South Dakota
Chuanbing Tang
Chuanbing Tang University of South Carolina
Nancy G. Klimas
Nancy G. Klimas Nova Southeastern University
Swapan K. Ray
Swapan K. Ray University of South Carolina
Bruce A. Lessey
Bruce A. Lessey Wake Forest Baptist Medical Center

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