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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
11692
World Ranking
10407
National Ranking
4517

Overview

James A. Carson is affiliated with the University of Tennessee Health Science Center in the United States. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology, with a strong emphasis on the physiological and molecular mechanisms related to muscle and chronic diseases.

Carson's recent publications highlight a focus on muscle physiology, immune responses, and the effects of exercise on health and disease. Notable recent papers include:

  • Inflammation, physical activity, and chronic disease: An evolutionary perspective (2020) published in Sports Medicine and Health Science
  • Mitochondria transplant therapy improves regeneration and restoration of injured skeletal muscle (2023) published in Journal of Cachexia Sarcopenia and Muscle
  • The Impact of Immune Cells on the Skeletal Muscle Microenvironment During Cancer Cachexia (2020) published in Frontiers in Physiology
  • Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery (2022) published in eLife
  • The Acute Effects of 5 Fluorouracil on Skeletal Muscle Resident and Infiltrating Immune Cells in Mice (2020) published in Frontiers in Physiology

The scientist frequently publishes in journals such as Medicine & Science in Sports & Exercise, The FASEB Journal, American Journal of Physiology-Cell Physiology, Sports Medicine and Health Science, and Journal of Cachexia Sarcopenia and Muscle. These venues reflect a consistent research activity in muscle physiology, rehabilitation, and exercise science.

Co-authorship collaborations are prominent in Carson's work, with frequent collaborators including:

  • Brittany R. Counts
  • Jessica L. Halle
  • Quan Zhang
  • Stephen E. Alway
  • Brandon N. VanderVeen

Their main areas of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, subfields targeted by Carson are:

  • Molecular Biology
  • Physiology
  • Oncology
  • Rehabilitation
  • Immunology

The primary topics addressed in their research involve:

  • Muscle Physiology and Disorders
  • Nutrition and Health in Aging
  • Exercise and Physiological Responses
  • Cancer survivorship and care
  • Adipose Tissue and Metabolism
  • Muscle metabolism and nutrition
  • Histone Deacetylase Inhibitors Research

This body of work reflects a multidisciplinary approach centered on understanding muscle function and health, particularly in relation to aging, cancer, metabolism, and immune interactions. The detailed investigation of muscle regeneration, inflammatory mechanisms, and responses to therapeutic interventions positions this scientist within the intersecting fields of medicine, molecular biology, and physiology.

Best Publications

  • CARBOHYDRATE INGESTION INFLUENCES SKELETAL MUSCLE CYTOKINE mRNA AND PLASMA CYTOKINE LEVELS AFTER A 3-H RUN

    D C. Nieman;J M. Davis;D A. Henson;J Walberg-Rankin

  • Interleukin-6 and cachexia in ApcMin/+ mice

    Kristen A. Baltgalvis;Franklin G. Berger;Maria Marjorette O. Pena;J. Mark Davis

  • The Regulation of Skeletal Muscle Protein Turnover during the Progression of Cancer Cachexia in the ApcMin/+ Mouse

    James P. White;John W. Baynes;Stephen L. Welle;Matthew C. Kostek

  • Influence of carbohydrate ingestion on immune changes after 2 h of intensive resistance training

    D. C. Nieman;J. M. Davis;V. A. Brown;D. A. Henson

  • Interleukin 6 as a key regulator of muscle mass during cachexia.

    James A. Carson;Kristen A. Baltgalvis

  • Mitochondrial degeneration precedes the development of muscle atrophy in progression of cancer cachexia in tumour-bearing mice

    Jacob L. Brown;Megan E. Rosa-Caldwell;David E. Lee;Thomas A. Blackwell

  • Testosterone regulation of Akt/mTORC1/FoxO3a signaling in skeletal muscle

    James P. White;Song Gao;Melissa J. Puppa;Shuichi Sato

  • IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the Apc Min/+ mouse

    James P White;Melissa J Puppa;Shuichi Sato;Song Gao

  • Role of interleukin-6 in cachexia: therapeutic implications.

    Aditi A Narsale;James A Carson

  • S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.

    Nathan L Alderson;Yuping Wang;Matthew Blatnik;Norma Frizzell

  • Focal adhesion proteins FAK and paxillin increase in hypertrophied skeletal muscle

    Martin Flück;James A. Carson;Scott E. Gordon;Andrew Ziemiecki

  • Myogenic regulatory factors during regeneration of skeletal muscle in young, adult, and old rats

    Daniel R. Marsh;David S. Criswell;James A. Carson;Frank W. Booth

  • Molecular and cellular adaptation of muscle in response to physical training

    F. W. Booth;B. S Tseng;M. Flück;J. A. Carson

  • Muscle oxidative capacity during IL-6-dependent cancer cachexia.

    James P. White;Kristen A. Baltgalvis;Melissa J. Puppa;Shuichi Sato

  • Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK.

    James P. White;Melissa J. Puppa;Song Gao;Shuichi Sato

  • Estrogen status and skeletal muscle recovery from disuse atrophy.

    J. M. McClung;J. M. Davis;M. A. Wilson;E. C. Goldsmith

  • Integrin signaling's potential for mediating gene expression in hypertrophying skeletal muscle.

    James A. Carson;Lei Wei

  • Disrupted Skeletal Muscle Mitochondrial Dynamics, Mitophagy, and Biogenesis during Cancer Cachexia: A Role for Inflammation.

    Brandon N. VanderVeen;Dennis K. Fix;James A. Carson

  • Muscle cytokine mRNA changes after 2.5 h of cycling: influence of carbohydrate.

    David C. Nieman;J. Mark Davis;Dru A. Henson;Sarah J. Gross

  • Counteracting muscle wasting in HIV-infected individuals

    WD Dudgeon;KD Phillips;JA Carson;RB Brewer

Frequent Co-Authors

John W. Baynes
John W. Baynes University of South Carolina
David C. Nieman
David C. Nieman Appalachian State University
Dru A. Henson
Dru A. Henson Appalachian State University
Mitzi Nagarkatti
Mitzi Nagarkatti University of South Carolina
Robert J. Schwartz
Robert J. Schwartz University of Houston
Prakash S. Nagarkatti
Prakash S. Nagarkatti University of South Carolina
Mark M. Davis
Mark M. Davis Stanford University
Suzanne R. Thorpe
Suzanne R. Thorpe University of South Carolina
Balaraman Kalyanaraman
Balaraman Kalyanaraman Medical College of Wisconsin
Ryoji Nagai
Ryoji Nagai Tokai University

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