World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
105
Citations
37363
World Ranking
1016
National Ranking
404

Research.com Recognitions

  • 2015 - Arthur C. Cope Award, American Chemical Society (ACS)
  • 2012 - Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry, Elsevier
  • 2003 - Member of the National Academy of Sciences
  • 2001 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1992 - Fellow of the American Academy of Arts and Sciences
  • 1988 - Ernest Guenther Award, American Chemical Society (ACS)
  • 1979 - Fellow of Alfred P. Sloan Foundation

Overview

Paul A. Wender is affiliated with Stanford University in the United States. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, medicine, immunology, and microbiology. Their work frequently appears in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Journal of the American Chemical Society, Nature Biotechnology, and Proceedings of the National Academy of Sciences.

The scientist has contributed to research in several interconnected fields of study, with a focus on molecular biology, immunology, infectious diseases, virology, and epidemiology. Their main topics of work include RNA interference and gene delivery, HIV research and treatment, advanced biosensing and bioanalysis techniques, immune cell function and interaction, HIV/AIDS drug development and treatment, HIV/AIDS research and interventions, and bacteriophages and microbial interactions.

Recent publications include:

  • Engineering circular RNA for enhanced protein production, 2022, Nature Biotechnology
  • Circular RNA vaccine induces potent T cell responses, 2023, Proceedings of the National Academy of Sciences
  • Latency reversal plus natural killer cells diminish HIV reservoir in vivo, 2022, Nature Communications
  • An mRNA SARS-CoV-2 Vaccine Employing Charge-Altering Releasable Transporters with a TLR-9 Agonist Induces Neutralizing Antibodies and T Cell Memory, 2021, ACS Central Science
  • Charge-altering releasable transporters enable phenotypic manipulation of natural killer cells for cancer immunotherapy, 2020, Blood Advances

Collaborative research has involved frequent coauthors including Robert M. Waymouth, Ronald Levy, Matthew D. Marsden, Jerome A. Zack, and Ole Audun Werner Haabeth.

Paul A. Wender has been recognized with several awards, such as the Arthur C. Cope Award from the American Chemical Society in 2015, the Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry from Elsevier in 2012, and election as a Member of the National Academy of Sciences in 2003. Additional honors include fellowships from the American Association for the Advancement of Science, the American Academy of Arts and Sciences, and the Alfred P. Sloan Foundation, as well as the Ernest Guenther Award from the American Chemical Society.

Best Publications

  • The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters

    Paul A. Wender;Dennis J. Mitchell;Kanaka Pattabiraman;Erin T. Pelkey

  • Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells.

    Nadine Wong Shi Kam;Theodore C Jessop;Paul A Wender;Hongjie Dai

  • Function-oriented synthesis, step economy, and drug design.

    Paul A. Wender;Vishal A. Verma;Thomas J. Paxton;Thomas H. Pillow

  • Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation

    Jonathan B. Rothbard;Sarah Garlington;Qun Lin;Thorsten Kirschberg

  • Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells.

    Jonathan B Rothbard;Theodore C Jessop;Richard S Lewis;Bryce A Murray

  • Synthesis at the molecular frontier

    Paul A. Wender;Benjamin L. Miller

  • Retrosynthetic Reaction Prediction Using Neural Sequence-to-Sequence Models

    Bowen Liu;Bharath Ramsundar;Prasad Kawthekar;Jade Shi

  • Taxol®: science and applications.

    M. Suffness;M. E. Wall;H. R. Hartzell;E. M. Croom

  • Arginine-Rich Molecular Transporters for Drug Delivery: Role of Backbone Spacing in Cellular Uptake

    Jonathan B. Rothbard;Erik Kreider;Christopher L. VanDeusen;Lee Wright

  • The design of guanidinium-rich transporters and their internalization mechanisms.

    Paul A. Wender;Wesley C. Galliher;Elena A. Goun;Lisa R. Jones

  • Transition Metal Catalyzed [5 + 2] Cycloadditions of Vinylcyclopropanes and Alkynes: A Homolog of the Diels-Alder Reaction for the Synthesis of Seven-Membered Rings

    Paul A. Wender;Hisashi Takahashi;Bernhard Witulski

  • Fifteen years of cell-penetrating, guanidinium-rich molecular transporters: basic science, research tools, and clinical applications.

    Erika Geihe Stanzl;Brian M. Trantow;Jessica R. Vargas;Paul A. Wender

  • Adaptive translocation : the role of hydrogen bonding and membrane potential in the uptake of guanidinium-rich transporters into cells

    Jonathan B. Rothbard;Theodore C. Jessop;Paul A. Wender

  • Compositions and methods for enhancing drug delivery across and into epithelial tissues

    Jonathan B. Rothbard;Paul A. Wender;P. Leo McGrane;Lalitha V. S. Sista

  • The Pinene Path to Taxanes. 6. A Concise Stereocontrolled Synthesis of Taxol

    Paul A. Wender;Neil F. Badham;Simon P. Conway;Paul E. Floreancig

  • Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters

    Elena A. Dubikovskaya;Steve H. Thorne;Thomas H. Pillow;Christopher H. Contag

  • The Pinene Path to Taxanes. 5. Stereocontrolled Synthesis of a Versatile Taxane Precursor

    Paul A. Wender;Neil F. Badham;Simon P. Conway;Paul E. Floreancig

  • Method and composition for enhancing transport across biological membranes

    Jonathan B. Rothbard;Paul A. Wender

  • Charge-altering releasable transporters (CARTs) for the delivery and release of mRNA in living animals

    Colin J. McKinlay;Jessica R. Vargas;Timothy R. Blake;Jonathan W. Hardy

  • Practical Synthesis of Prostratin, DPP, and Their Analogs, Adjuvant Leads Against Latent HIV

    Paul A. Wender;Jung-Min Kee;Jeffrey M. Warrington

  • Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C

    P A Wender;C M Cribbs;K F Koehler;N A Sharkey

Frequent Co-Authors

Robert M. Waymouth
Robert M. Waymouth Stanford University
Jonathan B. Rothbard
Jonathan B. Rothbard 180 Life Sciences
Jerome A. Zack
Jerome A. Zack University of California, Los Angeles
Lei Zhang
Lei Zhang South China University of Technology
Christopher H. Contag
Christopher H. Contag Michigan State University
Yoshimasa Nakamura
Yoshimasa Nakamura Okayama University
Kendall N. Houk
Kendall N. Houk University of California, Los Angeles
Zhi-Xiang Yu
Zhi-Xiang Yu Peking University
Peng Liu
Peng Liu University of Pittsburgh
Daesung Lee
Daesung Lee University of Illinois at Chicago

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