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Biology and Biochemistry

D-Index
49
Citations
9475
World Ranking
17981
National Ranking
1419

Overview

Rose Zamoyska is affiliated with the University of Edinburgh in the United Kingdom. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology. A significant proportion of their work focuses on immunology, molecular biology, and cancer-related subjects, reflecting a multidisciplinary approach to understanding cellular and molecular mechanisms.

The scientist's primary subfields of study include Immunology, Molecular Biology, Cancer Research, Oncology, and Genetics. Their research topics emphasize areas such as Immune Cell Function and Interaction, T-cell and B-cell Immunology, Cancer-related molecular mechanisms research, RNA Research and Splicing, Protein Tyrosine Phosphatases, CAR-T cell therapy research, and Galectins and Cancer Biology.

Rose Zamoyska has contributed to multiple high-profile journals. Notable recent publications include:

  • "A disease-linked lncRNA mutation in RNase MRP inhibits ribosome synthesis" (2022, Nature Communications)
  • "Modulation of TCR Signaling by Tyrosine Phosphatases: From Autoimmunity to Immunotherapy" (2020, Frontiers in Cell and Developmental Biology)
  • "Multi-color Molecular Visualization of Signaling Proteins Reveals How C-Terminal Src Kinase Nanoclusters Regulate T Cell Receptor Activation" (2020, Cell Reports)
  • "Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease" (2022, The Journal of Experimental Medicine)
  • "Translation factor eIF5a is essential for IFNγ production and cell cycle regulation in primary CD8+ T lymphocytes" (2022, Nature Communications)

Zamoyska's frequent co-authors include:

  • David J. Wright (8 collaborations)
  • Alexandra R. Teagle (4 collaborations)
  • Tony Ly (4 collaborations)
  • Vadim Shchepachev (3 collaborations)
  • Tomasz W. Turowski (3 collaborations)

Regarding publication venues, Zamoyska has multiple articles in:

  • bioRxiv (Cold Spring Harbor Laboratory), 6 publications
  • Nature Communications, 2 publications
  • Frontiers in Immunology, 2 publications
  • Frontiers in Cell and Developmental Biology, 1 publication
  • Cell Reports, 1 publication

Best Publications

  • T cell receptor signalling networks: branched, diversified and bounded

    Rebecca J. Brownlie;Rose Zamoyska

  • Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells.

    Benedict Seddon;Peter Tomlinson;Rose Zamoyska

  • T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance.

    Robert J. Salmond;Andrew Filby;Ihjaaz Qureshi;Stefano Caserta;Stefano Caserta

  • A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

    Martin Turner;P.Joseph Mee;Alice E Walters;Marian E Quinn

  • The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways.

    P. S. Costello;A. E. Walters;P. J. Mee;M. Turner

  • How Many Thymocytes Audition for Selection

    Matthias Merkenschlager;Daniel Graf;Matthew Lovatt;Ursula Bommhardt

  • Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes

    Jean Gabert;Claire Langlet;Rose Zamoyska;Jane R. Parnes

  • The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation.

    Rose Zamoyska;Albert Basson;Andrew Filby;Giuseppe Legname

  • Involvement of Avidity for Major Histocompatibility Complex in Homeostasis of Naive and Memory T Cells

    George Kassiotis;Rose Zamoyska;Brigitta Stockinger

  • Transfection of the CD8 gene enhances T-cell recognition

    Zlatko Dembić;Zlatko Dembić;Werner Haas;Werner Haas;Rose Zamoyska;Jane Parnes

  • Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.

    Rose Zamoyska;Paula Derham;Scott D. Gorman;Scott D. Gorman;Paul von Hoegen

  • TCR and IL-7 Receptor Signals Can Operate Independently or Synergize to Promote Lymphopenia-Induced Expansion of Naive T Cells

    Benedict Seddon;Rose Zamoyska

  • Sensory Adaptation in Naive Peripheral CD4 T Cells

    Katy Smith;Benedict Seddon;Marco A. Purbhoo;Rose Zamoyska

  • Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes

    Giuseppe Legname;Ben Seddon;Matthew Lovatt;Peter Tomlinson

  • TCR signals mediated by Src family kinases are essential for the survival of naive T cells

    Benedict Seddon;Rose Zamoyska

  • Two Lyt-2 polypeptides arise from a single gene by alternative splicing patterns of mRNA

    Rose Zamoyska;Amy C. Vollmer;Kurt C. Sizer;Chen W. Liaw

  • CD4 and CD8: modulators of T-cell receptor recognition of antigen and of immune responses?

    Rose Zamoyska

  • Long-Term Survival But Impaired Homeostatic Proliferation of Naïve T Cells in the Absence of p56lck

    Benedict Seddon;Giuseppe Legname;Peter Tomlinson;Rose Zamoyska

  • Self tolerance is H-2-restricted.

    Polly Matzinger;Polly Matzinger;Rose Zamoyska;Herman Waldmann

  • MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells

    Robert J. Salmond;Juliet Emery;Klaus Okkenhaug;Rose Zamoyska

Frequent Co-Authors

Andrew P. Cope
Andrew P. Cope King's College London
Hans J. Stauss
Hans J. Stauss University College London
Dimitris Kioussis
Dimitris Kioussis Medical Research Council
David J. Rawlings
David J. Rawlings Seattle Children's Hospital
Victor L. J. Tybulewicz
Victor L. J. Tybulewicz The Francis Crick Institute
Giuseppe Legname
Giuseppe Legname International School for Advanced Studies
Bernard Malissen
Bernard Malissen Aix-Marseille University
Emma Morris
Emma Morris University College London
Herman Waldmann
Herman Waldmann University of Oxford
Martin R. Turner
Martin R. Turner University of Oxford

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