What is he best known for?
The fields of study he is best known for:
Nunzio Bottini mainly investigates Protein tyrosine phosphatase, PTPN22, Immunology, Autoimmunity and Cell biology.
His Phosphatase research extends to Protein tyrosine phosphatase, which is thematically connected.
The study incorporates disciplines such as Internal medicine, Allele and T-cell receptor in addition to PTPN22.
His Allele research includes themes of SNP and Autoimmune disease.
His studies in Autoimmunity integrate themes in fields like Innate immune system and Antigen.
Nunzio Bottini focuses mostly in the field of Cell biology, narrowing it down to matters related to Tyrosine and, in some cases, Neuroscience.
His most cited work include:
- Protein Tyrosine Phosphatases in the Human Genome (1511 citations)
- A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes (1232 citations)
- Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. (629 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Protein tyrosine phosphatase, Immunology, Internal medicine, Biochemistry and Genetics.
His Protein tyrosine phosphatase study frequently draws connections to adjacent fields such as Phosphatase.
His research in Immunology intersects with topics in PTPN22 and Cancer research.
His PTPN22 study combines topics in areas such as Case-control study and Allele frequency.
Nunzio Bottini interconnects Diabetes mellitus, Endocrinology and Genotype in the investigation of issues within Internal medicine.
His work deals with themes such as T cell, T-cell receptor and Adipogenesis, which intersect with Cell biology.
He most often published in these fields:
- Protein tyrosine phosphatase (54.78%)
- Immunology (32.61%)
- Internal medicine (19.13%)
What were the highlights of his more recent work (between 2015-2021)?
- Protein tyrosine phosphatase (54.78%)
- Cancer research (13.04%)
- Phosphatase (21.30%)
In recent papers he was focusing on the following fields of study:
His main research concerns Protein tyrosine phosphatase, Cancer research, Phosphatase, Cell biology and Phosphorylation.
Biochemistry and Tyrosine are inherently bound to his Protein tyrosine phosphatase studies.
His research integrates issues of Tumor necrosis factor alpha, Rheumatoid arthritis, Immunology, Arthritis and Gene knockdown in his study of Cancer research.
His Rheumatoid arthritis research includes elements of Inflammation, PTPN22, Allele and Myeloid.
His Phosphatase study incorporates themes from Clonal anergy and Allosteric regulation.
The Cell biology study combines topics in areas such as Interleukin 2, CD8, Antigen and T-cell receptor.
Between 2015 and 2021, his most popular works were:
- Targeting Tyrosine Phosphatases: Time to End the Stigma. (64 citations)
- Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70. (34 citations)
- Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70. (34 citations)
In his most recent research, the most cited papers focused on:
Nunzio Bottini mainly focuses on Arthritis, Phosphatase, Biochemistry, Protein tyrosine phosphatase and Tyrosine.
His Arthritis study combines topics in areas such as Interferon gamma, Cytokine, Natural killer T cell, ZAP70 and Signal transduction.
His Phosphatase study introduces a deeper knowledge of Phosphorylation.
His Biochemistry study frequently draws connections between related disciplines such as Computational biology.
His Type 2 diabetes study often links to related topics such as Pharmacology.
The various areas that he examines in his Pharmacology study include Human serum albumin, Methotrexate, Drug delivery, Albumin and Cysteine.
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