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Toshiaki Isobe

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
19993
World Ranking
4371
National Ranking
283

Toshiaki Isobe publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Toshiaki Isobe sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 272 publications — 73rd percentile

73% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Toshiaki Isobe D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Toshiaki Isobe sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 79 D-Index — 79th percentile

79% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Toshiaki Isobe is affiliated with Tokyo Metropolitan University in Japan. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus on molecular biology and related subfields.

The scientist's recent publications cover a range of topics pertinent to RNA modifications, protein synthesis mechanisms, and parasitic infections. Notable papers include:

  • Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping (2020), published in Nature
  • DKC1 Overexpression Induces a More Aggressive Cellular Behavior and Increases Intrinsic Ribosomal Activity in Immortalized Mammary Gland Cells (2020), published in Cancers
  • Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis (2020), published in Nucleic Acids Research
  • Direct Determination of Pseudouridine in RNA by Mass Spectrometry Coupled with Stable Isotope Labeling (2020), published in Analytical Chemistry
  • A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei (2023), published in Nature Communications

The main topics covered in their work include:

  • RNA modifications and cancer
  • RNA and protein synthesis mechanisms
  • Immune response and inflammation
  • RNA research and splicing
  • Neonatal health and biochemistry
  • Trypanosoma species research and implications
  • Parasitic infections and diagnostics

Frequent coauthors collaborating with Toshiaki Isobe are:

  • Masato Taoka
  • Yuko Nobe
  • Yoshio Yamauchi
  • Anat Bashan
  • Ada Yonath

The scientist has published multiple works in leading venues, including:

  • Nucleic Acids Research
  • The Journal of Experimental Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Communications

Within their subfields of study, Toshiaki Isobe's research includes molecular biology, immunology, epidemiology, surgery, and physiology. This multidisciplinary approach contributes to understanding complex biological processes related to RNA and protein function, immune responses, and parasitic diseases.

Best Publications

  • Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

    Kohichi Matsunaga;Tatsuya Saitoh;Keisuke Tabata;Hiroko Omori

  • Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins

    Hiroyuki Kaji;Haruna Saito;Yoshio Yamauchi;Takashi Shinkawa

  • Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases

    Tohru Ichimura;Toshiaki Isobe;Tsuneo Okuyama;Nobuhiro Takahashi

  • The amino-acid sequence of S-100 protein (PAP I-b protein) and its relation to the calcium-binding proteins.

    Toshiaki Isobe;Tsuneo Okuyama

  • Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.

    Zhikuan Zhang;Umeharu Ohto;Takuma Shibata;Elena Krayukhina

  • Immunohistochemical study on the distribution of α and β subunits of S-100 protein in human neoplasm and normal tissues

    Kiyoshi Takahashi;Toshiaki Isobe;Yuji Ohtsuki;Tadaatsu Akagi

  • Brain 14-3-3 protein is an activator protein that activates tryptophan 5-monooxygenase and tyrosine 3-monooxygenase in the presence of Ca2+,calmodulin-dependent protein kinase II

    Tohru Ichimura;Toshiaki Isobe;Tsueno Okuyama;Takashi Yamauchi

  • Epiregulin: A NOVEL EPIDERMAL GROWTH FACTOR WITH MITOGENIC ACTIVITY FOR RAT PRIMARY HEPATOCYTES ∗

    Hitoshi Toyoda;Toshi Komurasaki;Daisuke Uchida;Yasuko Takayama

  • Toll-like receptor 8 senses degradation products of single-stranded RNA.

    Hiromi Tanji;Umeharu Ohto;Takuma Shibata;Masato Taoka

  • The Amino-Acid Sequence of the α Subunit in Bovine Brain S-100a Protein

    Toshiaki Isobe;Tsuneo Okuyama

  • Phosphorylation of αB-Crystallin in Response to Various Types of Stress

    Hidenori Ito;Keiko Okamoto;Hiroshi Nakayama;Toshiaki Isobe

  • Landscape of the complete RNA chemical modifications in the human 80S ribosome

    Masato Taoka;Yuko Nobe;Yuka Yamaki;Ko Sato

  • Reinvestigation of extremely acidic proteins in bovine brain

    Toshiaki Isobe;Toshiaki Nakajima;Tsuneo Okuyama

  • The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1

    Antoni Matilla;Beena T. Koshy;Christopher J. Cummings;Toshiaki Isobe

  • Molecular constituents of the postsynaptic density fraction revealed by proteomic analysis using multidimensional liquid chromatography-tandem mass spectrometry.

    Yoshiyuki Yoshimura;Yoshio Yamauchi;Takashi Shinkawa;Masato Taoka

  • 14-3-3 Proteins Modulate the Expression of Epithelial Na+ Channels by Phosphorylation-dependent Interaction with Nedd4-2 Ubiquitin Ligase

    Tohru Ichimura;Hisao Yamamura;Kaname Sasamoto;Yuri Tominaga

  • Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping

    Aldema Sas-Chen;Justin M. Thomas;Donna Matzov;Masato Taoka

  • A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics.

    Tohru Natsume;Yoshio Yamauchi;Hiroshi Nakayama;Takashi Shinkawa

  • Structural Relation of Two S‐100 Proteins in Bovine Brain; Subunit Composition of S‐100 a Protein

    Toshiaki Isobe;Noriaki Ishioka;Tsuneo Okuyama

  • S100a0 (αα) Protein Is Present in Neurons of the Central and Peripheral Nervous System

    Toshiaki Isobe;Kiyoshi Takahashi;Tsuneo Okuyama

Frequent Co-Authors

Nobuhiro Takahashi
Nobuhiro Takahashi Tokyo University of Agriculture and Technology
Yasuo Takahashi
Yasuo Takahashi Niigata University
Ryozo Kuwano
Ryozo Kuwano Niigata University
Richard J. Simpson
Richard J. Simpson La Trobe University
Tohru Natsume
Tohru Natsume National Institute of Advanced Industrial Science and Technology
Shin-ichi Hisanaga
Shin-ichi Hisanaga Tokyo Metropolitan University
Hisatake Kondo
Hisatake Kondo Tohoku University
Jinrong Min
Jinrong Min Structural Genomics Consortium
Kensuke Miyake
Kensuke Miyake Tokyo University of Science
Naohiko Koshikawa
Naohiko Koshikawa Tokyo Institute of Technology

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Best Scientists Citing Toshiaki Isobe

Tohru Natsume

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Publications: 87

Shun-ichiro Iemura

Shun-ichiro Iemura

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Hiroyoshi Hidaka

Hiroyoshi Hidaka

D. Western Therapeutics Institute (Japan)

Publications: 58

Tamotsu Yoshimori

Tamotsu Yoshimori

Osaka University

Publications: 40

Masahiko Watanabe

Masahiko Watanabe

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Publications: 35

Rosario Donato

Rosario Donato

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Publications: 34

Kanefusa Kato

Kanefusa Kato

Nagoya University

Publications: 32

Nobuhiro Takahashi

Nobuhiro Takahashi

Tokyo University of Agriculture and Technology

Publications: 30

Jacques Baudier

Jacques Baudier

Aix-Marseille University

Publications: 30

Hisashi Narimatsu

Hisashi Narimatsu

National Institute of Advanced Industrial Science and Technology

Publications: 26

Beth Levine

Beth Levine

The University of Texas Southwestern Medical Center

Publications: 26

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Tomoichiro Asano

Hiroshima University

Publications: 25

Shin-ichi Hisanaga

Shin-ichi Hisanaga

Tokyo Metropolitan University

Publications: 23

Robert J. Ferl

Robert J. Ferl

University of Florida

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Yasuo Takahashi

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