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Shun-ichiro Iemura

Shun-ichiro Iemura

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
20996
World Ranking
12280
National Ranking
844

Overview

Shun-ichiro Iemura is affiliated with Fukushima Medical University in Japan. Their research spans key areas within biochemistry, genetics, and molecular biology, with significant contributions also in immunology and microbiology.

They have published extensively on topics relating to interferon and immune responses, RNA research and splicing, RNA regulation and disease, autophagy in disease and therapy, ubiquitin and proteasome pathways, RNA modifications and cancer, and peroxisome proliferator-activated receptors.

Notable recent publications include:

  • Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteins during mitophagy, 2021, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • NUDT21 Links Mitochondrial IPS-1 to RLR-Containing Stress Granules and Activates Host Antiviral Defense, 2020, The Journal of Immunology
  • Membrane topology inversion of GGCX mediates cytoplasmic carboxylation for antiviral defense, 2025, Science
  • NUDT21 links mitochondrial IPS-1 to RLR-containing stress granules and activates host antiviral defense, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Iemura's work has appeared in several publication venues, including:

  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • The Journal of Immunology
  • Science
  • bioRxiv (Cold Spring Harbor Laboratory)

Their research collaborations include frequent co-authors such as Tohru Natsume, Tomohiko Okazaki, Yukiko Gotoh, Saeko Aoyama-Ishiwatari, and Yasushi Okada.

The scientist's subfields cover molecular biology, immunology, and epidemiology, reflecting a multidisciplinary approach to understanding molecular mechanisms linked to immune defense and RNA biology.

Best Publications

  • The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

    Masaaki Komatsu;Hirofumi Kurokawa;Satoshi Waguri;Keiko Taguchi

  • Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

    Nao Hosokawa;Taichi Hara;Takeshi Kaizuka;Chieko Kishi

  • Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice

    Masaaki Komatsu;Satoshi Waguri;Masato Koike;Yu shin Sou;Yu shin Sou

  • FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

    Taichi Hara;Akito Takamura;Chieko Kishi;Shun Ichiro Iemura

  • Shugoshin collaborates with protein phosphatase 2A to protect cohesin

    Tomoya S. Kitajima;Takeshi Sakuno;Kei-ichiro Ishiguro;Shun-ichiro Iemura

  • Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo

    Shun Ichiro Iemura;Takamasa S. Yamamoto;Chiyo Takagi;Hideho Uchiyama

  • Atg101, a novel mammalian autophagy protein interacting with Atg13

    Nao Hosokawa;Takahiro Sasaki;Shun Ichiro Iemura;Tohru Natsume

  • WNK1 Regulates Phosphorylation of Cation-Chloride-coupled Cotransporters via the STE20-related Kinases, SPAK and OSR1

    Tetsuo Moriguchi;Seiichi Urushiyama;Naoki Hisamoto;Shun Ichiro Iemura

  • A functional bone morphogenetic protein system in the ovary

    S. Shimasaki;R. J. Zachow;Danmei Li;H. Kim

  • Skp2-mediated degradation of p27 regulates progression into mitosis.

    Keiko Nakayama;Hiroyasu Nagahama;Yohji A. Minamishima;Satoshi Miyake

  • A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier

    Masaaki Komatsu;Tomoki Chiba;Kanako Tatsumi;Shun-ichiro Iemura

  • Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

    Shinichiro Nakada;Ikue Tai;Stephanie Panier;Stephanie Panier;Abdallah Al-Hakim

  • Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly

    Takeshi Kaizuka;Taichi Hara;Noriko Oshiro;Ushio Kikkawa

  • Bone Morphogenetic Protein 2 Stimulates Osteoclast Differentiation and Survival Supported by Receptor Activator of Nuclear Factor-κB Ligand

    Kanami Itoh;Nobuyuki Udagawa;Takenobu Katagiri;Shunichiro Iemura

  • A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes

    Yuko Hirano;Klavs B. Hendil;Hideki Yashiroda;Shun-ichiro Iemura

  • A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes.

    Jun Hamazaki;Jun Hamazaki;Shun-ichiro Iemura;Tohru Natsume;Hideki Yashiroda

  • Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.

    Takeumi Kaneko;Jun Hamazaki;Shun-ichiro Iemura;Katsuhiro Sasaki

  • A novel type of E3-ligase for the Ufm1-conjugation system

    Kanako Tatsumi;Yu Shin Sou;Yu Shin Sou;Norihiro Tada;Eri Nakamura

  • Action range of BMP is defined by its N-terminal basic amino acid core.

    Bisei Ohkawara;Bisei Ohkawara;Shun-ichiro Iemura;Peter ten Dijke;Naoto Ueno;Naoto Ueno

  • WNK1 Regulates Phosphorylation of Cation-Chloride- coupled Cotransporters via the STE20-related Kinases,

    Tetsuo Moriguchi;Seiichi Urushiyama;Naoki Hisamoto;Shun-ichiro Iemura

Frequent Co-Authors

Tohru Natsume
Tohru Natsume National Institute of Advanced Industrial Science and Technology
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Hiroshi Shibuya
Hiroshi Shibuya Tokyo Medical and Dental University
Shigeo Murata
Shigeo Murata University of Tokyo
Masayuki Yamamoto
Masayuki Yamamoto Tohoku University
Kunihiro Matsumoto
Kunihiro Matsumoto Nagoya University
Naoto Ueno
Naoto Ueno National Institute for Basic Biology
Masaaki Komatsu
Masaaki Komatsu Juntendo University
Noboru Mizushima
Noboru Mizushima University of Tokyo
Kazuhiro Nagata
Kazuhiro Nagata Kyoto Sangyo University

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