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Molecular Biology

D-Index
71
Citations
26031
World Ranking
1349
National Ranking
115

Overview

Tohru Natsume is affiliated with the National Institute of Advanced Industrial Science and Technology in Japan. Their research primarily focuses on fields within biochemistry, genetics, and molecular biology, with significant contributions in medicine.

Their main subfields of study comprise molecular biology, epidemiology, biomedical engineering, cancer research, and immunology. Key topics within their body of work include RNA research and splicing, RNA modifications and cancer, herpesvirus infections and treatments, cancer-related molecular mechanisms research, ubiquitin and proteasome pathways, RNA and protein synthesis mechanisms, and interferon and immune responses.

Tohru Natsume's recent publications demonstrate a focus on molecular and cellular biology topics. Some notable papers include:

  • "Robotic search for optimal cell culture in regenerative medicine" (2022) published in eLife
  • "m 6 A modification of HSATIII lncRNAs regulates temperature-dependent splicing" (2021) published in The EMBO Journal
  • "The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3" (2022) published in Nature Communications
  • "Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival" (2021) published in Cell Reports
  • "ERdj8 governs the size of autophagosomes during the formation process" (2020) published in The Journal of Cell Biology

Their collaborative work includes frequent partnerships with researchers such as Shungo Adachi, Tomohisa Hatta, Naoto Koyanagi, Yuhei Maruzuru, and Yasushi Kawaguchi.

Publication venues where Tohru Natsume has contributed multiple times include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Cell Biology
  • Scientific Reports
  • Nature Communications
  • Cell Reports

Best Publications

  • The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

    Masaaki Komatsu;Hirofumi Kurokawa;Satoshi Waguri;Keiko Taguchi

  • Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

    Nao Hosokawa;Taichi Hara;Takeshi Kaizuka;Chieko Kishi

  • Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice

    Masaaki Komatsu;Satoshi Waguri;Masato Koike;Yu shin Sou;Yu shin Sou

  • FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

    Taichi Hara;Akito Takamura;Chieko Kishi;Shun Ichiro Iemura

  • Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

    Noboru Mizushima;Noboru Mizushima;Akiko Kuma;Akiko Kuma;Yoshinori Kobayashi;Yoshinori Kobayashi;Akitsugu Yamamoto

  • Shugoshin collaborates with protein phosphatase 2A to protect cohesin

    Tomoya S. Kitajima;Takeshi Sakuno;Kei-ichiro Ishiguro;Shun-ichiro Iemura

  • Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo

    Shun Ichiro Iemura;Takamasa S. Yamamoto;Chiyo Takagi;Hideho Uchiyama

  • Atg101, a novel mammalian autophagy protein interacting with Atg13

    Nao Hosokawa;Takahiro Sasaki;Shun Ichiro Iemura;Tohru Natsume

  • WNK1 Regulates Phosphorylation of Cation-Chloride-coupled Cotransporters via the STE20-related Kinases, SPAK and OSR1

    Tetsuo Moriguchi;Seiichi Urushiyama;Naoki Hisamoto;Shun Ichiro Iemura

  • The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17

    Peidu Jiang;Taki Nishimura;Taki Nishimura;Yuriko Sakamaki;Eisuke Itakura

  • Subtype-Specific and ER Lumenal Environment-Dependent Regulation of Inositol 1,4,5-Trisphosphate Receptor Type 1 by ERp44

    Takayasu Higo;Mitsuharu Hattori;Mitsuharu Hattori;Takeshi Nakamura;Tohru Natsume

  • Skp2-mediated degradation of p27 regulates progression into mitosis.

    Keiko Nakayama;Hiroyasu Nagahama;Yohji A. Minamishima;Satoshi Miyake

  • A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier

    Masaaki Komatsu;Tomoki Chiba;Kanako Tatsumi;Shun-ichiro Iemura

  • Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

    Shinichiro Nakada;Ikue Tai;Stephanie Panier;Stephanie Panier;Abdallah Al-Hakim

  • Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly

    Takeshi Kaizuka;Taichi Hara;Noriko Oshiro;Ushio Kikkawa

  • JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage

    Kiyotsugu Yoshida;Tomoko Yamaguchi;Tohru Natsume;Donald Kufe

  • A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes

    Yuko Hirano;Klavs B. Hendil;Hideki Yashiroda;Shun-ichiro Iemura

  • A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes.

    Jun Hamazaki;Jun Hamazaki;Shun-ichiro Iemura;Tohru Natsume;Hideki Yashiroda

  • Intrinsically Disordered Protein TEX264 Mediates ER-phagy.

    Haruka Chino;Tomohisa Hatta;Tohru Natsume;Noboru Mizushima

  • WNK1 Regulates Phosphorylation of Cation-Chloride- coupled Cotransporters via the STE20-related Kinases,

    Tetsuo Moriguchi;Seiichi Urushiyama;Naoki Hisamoto;Shun-ichiro Iemura

Frequent Co-Authors

Shun-ichiro Iemura
Shun-ichiro Iemura Fukushima Medical University
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Shigeo Murata
Shigeo Murata University of Tokyo
Kazuhiro Nagata
Kazuhiro Nagata Kyoto Sangyo University
Hiroshi Shibuya
Hiroshi Shibuya Tokyo Medical and Dental University
Kazuo Shin-ya
Kazuo Shin-ya National Institute of Advanced Industrial Science and Technology
Noboru Mizushima
Noboru Mizushima University of Tokyo
Katsuhiko Mikoshiba
Katsuhiko Mikoshiba ShanghaiTech University
Toshiaki Isobe
Toshiaki Isobe Tokyo Metropolitan University
Hidenori Ichijo
Hidenori Ichijo University of Tokyo

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