World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
15828
World Ranking
14207
National Ranking
1005

Overview

Daisuke Kitamura is affiliated with Tokyo University of Science in Japan and focuses research primarily in the domains of Immunology and Microbiology as well as Medicine. Their work spans several interrelated subfields including Immunology, Molecular Biology, Nephrology, Pathology and Forensic Medicine, and Physiology.

Their research covers a range of topics, prominently featuring aspects of immune cell function and interaction, T-cell and B-cell immunology, immunotherapy and immune responses, renal diseases and glomerulopathies, immune response and inflammation, asthma and respiratory diseases, and RNA interference and gene delivery.

Kitamura has published extensively, with notable contributions appearing in publication venues such as International Immunology, Cell Reports, The Journal of Experimental Medicine, The Journal of Immunology, and Kidney International Reports. The frequency of publications suggests a strong emphasis on immunological research and related medical science.

Frequent coauthors include Kei Haniuda, Saori Fukao, Yoshihito Nihei, Yusuke Suzuki, and Mizuki Higashiyama, indicating collaborative work across multiple studies and projects.

Some recent significant papers include:

  • Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling, 2020, Cell Reports
  • An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment, 2022, Science Immunology
  • Identification of IgA autoantibodies targeting mesangial cells redefines the pathogenesis of IgA nephropathy, 2023, Science Advances
  • Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9, 2022, Nature Communications
  • DNASE1L3 enhances antitumor immunity and suppresses tumor progression in colon cancer, 2023, JCI Insight

Best Publications

  • A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

    Daisuke Kitamura;Jürgen Roes;Ralf Kühn;Klaus Rajewsky

  • A critical role of λ5 protein in B cell development

    Daisuke Kitamura;Akira Kudo;Stefan Schaal;Werner Müller

  • Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

    Hirofumi Nishizumi;Ichiro Taniuchi;Yuji Yamanashi;Daisuke Kitamura

  • Host DNases prevent vascular occlusion by neutrophil extracellular traps

    Miguel Jiménez-Alcázar;Chandini Rangaswamy;Rachita Panda;Josephine Bitterling

  • Targeted disruption of µ chain membrane exon causes loss of heavy-chain allelic exclusion

    Daisuke Kitamura;Daisuke Kitamura;Klaus Rajewsky

  • Immunoglobulin heavy and light chain genes rearrange independently at early stages of B cell development

    Andreas Ehlich;Stefan Schaal;Hua Gu;Daisuke Kitamura

  • FcεRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane

    Keigo Nishida;Satoru Yamasaki;Yukitaka Ito;Koki Kabu

  • In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo

    Takuya Nojima;Kei Haniuda;Tatsuya Moutai;Moeko Matsudaira

  • HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases.

    Yasuhiro Suzuki;Corinne Demoliere;Daisuke Kitamura;Hiromichi Takeshita

  • Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

    Masahiro Shinohara;Takako Koga;Kazuo Okamoto;Shinya Sakaguchi

  • Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors

    Isao Inoue;Kazuhiko Yanai;Daisuke Kitamura;Ichiro Taniuchi

  • Complex Antigens Drive Permissive Clonal Selection in Germinal Centers

    Masayuki Kuraoka;Aaron G. Schmidt;Takuya Nojima;Feng Feng

  • Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis

    Marieta Caganova;Chiara Carrisi;Gabriele Varano;Federica Mainoldi

  • B cell development regulated by gene rearrangement: Arrest of maturation by membrane-bound Dμ protein and selection of DH element reading frames

    Hua Gu;Daisuke Kitamura;Klaus Rajewsky

  • Direct evidence for the contribution of B cells to the progression of insulitis and the development of diabetes in non-obese diabetic mice

    Tomoyuki Akashi;Seiho Nagafuchi;Keizo Anzai;Shiori Kondo

  • IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases.

    S Sato;T Katagiri;S Takaki;Y Kikuchi

  • Glycosylphosphatidylinositol-anchor-deficient mice: implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria

    Kazuyoshi Kawagoe;Daisuke Kitamura;Masaru Okabe;Ichiro Taniuchi

  • Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage.

    D Kitamura;H Kaneko;Y Miyagoe;T Ariyasu

  • Cell cycle arrest and apoptosis induced by Notch1 in B cells.

    Toshifumi Morimura;Ryo Goitsuka;Ryo Goitsuka;Yong Zhang;Izumu Saito

  • Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling.

    Yuji Yamanashi;Masato Okada;Toshihiko Semba;Takashi Yamori

Frequent Co-Authors

Katsuhiko Hayashi
Katsuhiko Hayashi Osaka University
Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Ichiro Taniuchi
Ichiro Taniuchi RIKEN Center for Integrative Medical Sciences
Tomohiro Kurosaki
Tomohiro Kurosaki Osaka University
Akira Kudo
Akira Kudo Tokyo Institute of Technology
Max D. Cooper
Max D. Cooper Emory University
Tadashi Yamamoto
Tadashi Yamamoto Okinawa Institute of Science and Technology
Raif S. Geha
Raif S. Geha Boston Children's Hospital
Werner Müller
Werner Müller University of Manchester
Garnett Kelsoe
Garnett Kelsoe Duke University

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