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Immunology

D-Index
110
Citations
52906
World Ranking
493
National Ranking
44

Medicine

D-Index
111
Citations
54307
World Ranking
5274
National Ranking
521

Research.com Recognitions

  • 2015 - Member of Academia Europaea

Overview

Werner Müller is affiliated with the University of Manchester in the United Kingdom. Their primary research areas span immunology and microbiology as well as biochemistry, genetics, and molecular biology. Within these fields, Müller focuses on several subfields including immunology, molecular biology, oncology, genetics, and biomedical engineering.

The scientist's work addresses a range of topics, such as immune cells in cancer, immune response and inflammation, single-cell and spatial transcriptomics, immune cell function and interaction, CAR-T cell therapy research, immunotherapy and immune responses, and IL-33, ST2, and ILC pathways.

Müller has contributed to numerous publications, with recent papers including:

  • Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge (2020) - Immunity
  • MACSima imaging cyclic staining (MICS) technology reveals combinatorial target pairs for CAR T cell treatment of solid tumors (2022) - Scientific Reports
  • A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System (2020) - The Journal of Immunology
  • The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function (2020) - Frontiers in Immunology
  • Multiplexed histology analyses for the phenotypic and spatial characterization of human innate lymphoid cells (2021) - Nature Communications

Frequent coauthors in their research include Andreas Bosio, Silvia Rüberg, Paurush Praveen, Dongju Park, and Michael DiBuono.

Müller regularly publishes in several well-known venues including bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Frontiers in Immunology, Nature Communications, and PLoS Pathogens.

Their work has been recognized by the awarding of membership in the Academia Europaea in 2015.

Best Publications

  • Interleukin-10-deficient mice develop chronic enterocolitis

    Ralf Kühn;Jürgen Löhler;Donna Rennick;Klaus Rajewsky

  • High gradient magnetic cell separation with MACS

    Stefan Miltenyi;Werner Müller;Walter Weichel;Andreas Radbruch

  • Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

    Yuri P. Rubtsov;Jeffrey P. Rasmussen;Emil Y. Chi;Jason Fontenot

  • Altered immune responses in mice lacking inducible nitric oxide synthase

    Xiao-Qing Wei;Ian G. Charles;Austin Smith;Jan Ure

  • Generation and analysis of interleukin-4 deficient mice.

    R. Kühn;K. Rajewsky;W. Müller

  • ENTEROCOLITIS AND COLON CANCER IN INTERLEUKIN-10 : DEFICIENT MICE ARE ASSOCIATED WITH ABERRANT CYTOKINE PRODUCTION AND CD4+ TH1-LIKE RESPONSES

    Daniel J. Berg;Natalle Davidson;Ralf Kühn;Werner Müller

  • Differential Roles of Macrophages in Diverse Phases of Skin Repair

    Tina Lucas;Ari Waisman;Rajeev Ranjan;Jürgen Roes

  • In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha.

    Ricardo T. Gazzinelli;M. Wysocka;S Hieny;T Scharton-Kersten

  • Interleukin-10 signaling in regulatory T cells Is required for suppression of Th17 cell-mediated inflammation

    Ashutosh Chaudhry;Robert M. Samstein;Piper Treuting;Yuqiong Liang

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Mübeccel Akdis

  • Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

    James P. Disanto;Werner Muller;Delphine Guy-Grand;Alain Fischer

  • Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria

    Usriansyah Hadis;Benjamin Wahl;Olga Schulz;Matthias Hardtke-Wolenski

  • Loss of a gp130 Cardiac Muscle Cell Survival Pathway Is a Critical Event in the Onset of Heart Failure during Biomechanical Stress

    Hisao Hirota;Ju Chen;Ulrich A.K Betz;Klaus Rajewsky

  • A critical role of λ5 protein in B cell development

    Daisuke Kitamura;Akira Kudo;Stefan Schaal;Werner Müller

  • Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

    Norbert Wagner;Jürgen Löhler;Eric J. Kunkel;Klaus Ley

  • Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System.

    Julia Bruttger;Khalad Karram;Simone Wörtge;Tommy Regen

  • Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance.

    Daniel J. Berg;Ralf Kuhn;Klaus Rajewsky;Werner Muller

  • IMGT, the international ImMunoGeneTics database

    Unknown

  • Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

    Dror S. Shouval;Dror S. Shouval;Amlan Biswas;Amlan Biswas;Jeremy A. Goettel;Jeremy A. Goettel;Katelyn McCann

  • Conditional gene targeting

    K. Rajewsky;H. Gu;R. Kuhn;U. A. K. Betz

  • In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal

    Ricardo Tostes Gazzinelli;Maria Wysocka;Sara Hieny;Tanya M Scharton-Kersten

Frequent Co-Authors

Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Ralf Kühn
Ralf Kühn Max Delbrück Center for Molecular Medicine
Axel Roers
Axel Roers University Hospital Heidelberg
Ari Waisman
Ari Waisman Johannes Gutenberg University of Mainz
Thomas Krieg
Thomas Krieg University of Cologne
Reinhold Förster
Reinhold Förster Hannover Medical School
Scott B. Snapper
Scott B. Snapper Boston Children's Hospital
Alan Sher
Alan Sher National Institute of Allergy and Infectious Diseases
Donna Rennick
Donna Rennick MSD (United States)

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