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Karin Scharffetter-Kochanek

Karin Scharffetter-Kochanek

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
24490
World Ranking
3327
National Ranking
251

Research.com Recognitions

  • 2008 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Internal Medicine and Dermatology

Overview

Karin Scharffetter-Kochanek is affiliated with the University of Ulm in Germany. Their research focuses primarily on medicine and biochemistry, genetics, and molecular biology, contributing extensively to subfields such as molecular biology, dermatology, epidemiology, oncology, and genetics.

The main topics of their work include:

  • Skin Protection and Aging
  • Wound Healing and Treatments
  • Nonmelanoma Skin Cancer Studies
  • Mesenchymal Stem Cell Research
  • Telomeres, Telomerase, and Senescence
  • Cutaneous Melanoma Detection and Management
  • Autoimmune Bullous Skin Diseases

Scharffetter-Kochanek has published in a variety of scientific venues, with frequent contributions to:

  • JDDG Journal der Deutschen Dermatologischen Gesellschaft (16 publications)
  • Journal of Investigative Dermatology (15 publications)
  • EMBO Reports (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)
  • Acta Dermato Venereologica (3 publications)

Recent papers include:

  • "Connective Tissue and Fibroblast Senescence in Skin Aging," 2021, Journal of Investigative Dermatology
  • "Guidelines for Minimal Information on Cellular Senescence Experimentation In Vivo," 2024, Cell
  • "Mesenchymal Stem Cells Adaptively Respond to Environmental Cues Thereby Improving Granulation Tissue Formation and Wound Healing," 2020, Frontiers in Cell and Developmental Biology
  • "Translational Development of ABCB5+ Dermal Mesenchymal Stem Cells for Therapeutic Induction of Angiogenesis in Non-Healing Diabetic Foot Ulcers," 2022, Stem Cell Research & Therapy
  • "TLR4-Dependent Shaping of the Wound Site by MSCs Accelerates Wound Healing," 2020, EMBO Reports

Frequent co-authors collaborating with Scharffetter-Kochanek include:

  • Diana Crișan (26 collaborations)
  • Pallab Maity (23 collaborations)
  • Karmveer Singh (17 collaborations)
  • Meinhard Wlaschek (16 collaborations)
  • Maria Crişan (13 collaborations)

Throughout their career, Scharffetter-Kochanek has been recognized by institutions such as the German National Academy of Sciences Leopoldina in 2008 for contributions related to internal medicine and dermatology.

Best Publications

  • An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

    Anca Sindrilaru;Thorsten Peters;Stefan Wieschalka;Corina Baican

  • p16INK4A is a robust in vivo biomarker of cellular aging in human skin.

    Sigrun Ressler;Jirina Bartkova;Harald Niederegger;Jiri Bartek

  • Solar UV irradiation and dermal photoaging

    Meinhard Wlaschek;Iliana Tantcheva-Poór;Lale Naderi;Wenjian Ma

  • CDC42 ACTIVITY REGULATES HEMATOPOIETIC STEM CELL AGING AND REJUVENATION

    Maria Carolina Florian;Karin Dörr;Anja Niebel;Deidre Daria

  • UV-induced reactive oxygen species in photocarcinogenesis and photoaging.

    Scharffetter-Kochanek K;Wlaschek M;Brenneisen P;Schauen M

  • Ultraviolet-B Irradiation and Matrix Metalloproteinases

    Peter Brenneisen;Helmut Sies;Karin Scharffetter-Kochanek

  • Spontaneous Skin Ulceration and Defective T Cell Function in CD18 Null Mice

    Karin Scharffetter-Kochanek;Karin Scharffetter-Kochanek;Huifang Lu;Keith Norman;Nicole van Nood

  • Role of β2-integrins for homing and neovascularization capacity of endothelial progenitor cells

    Emmanouil Chavakis;Alexandra Aicher;Christopher Heeschen;Ken-ichiro Sasaki

  • Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo.

    Unsu Jung;Keith E. Norman;Karin Scharffetter-Kochanek;Arthur L. Beaudet

  • UVA-induced autocrine stimulation of fibroblast-derived collagenase/MMP-1 by interrelated loops of interleukin-1 and interleukin-6.

    Meinhard Wlaschek;Gudrun Heinen;Arndt Poswig;Agatha Schwarz

  • Stable Overexpression of Manganese Superoxide Dismutase in Mitochondria Identifies Hydrogen Peroxide as a Major Oxidant in the AP-1-mediated Induction of Matrix-degrading Metalloprotease-1

    Jutta Wenk;Peter Brenneisen;Meinhard Wlaschek;Arndt Poswig

  • Activated macrophages are essential in a murine model for T cell–mediated chronic psoriasiform skin inflammation

    Honglin Wang;Thorsten Peters;Daniel Kess;Anca Sindrilaru

  • Central Role of Ferrous/Ferric Iron in the Ultraviolet B Irradiation-mediated Signaling Pathway Leading to Increased Interstitial Collagenase (Matrix-degrading Metalloprotease (MMP)-1) and Stromelysin-1 (MMP-3) mRNA Levels in Cultured Human Dermal Fibroblasts

    Peter Brenneisen;Jutta Wenk;L. Oliver Klotz;Meinhard Wlaschek

  • Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

    Joseph P. Mizgerd;Hiroshi Kubo;Gregory J. Kutkoski;Sabrina D. Bhagwan

  • A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing

    Maria Carolina Florian;Kalpana J. Nattamai;Karin Dörr;Gina Marka

  • Singlet Oxygen May Mediate the Ultraviolet A-Induced Synthesis of Interstitial Collagenase

    Meinhard Wlaschek;Karlis Briviba;George P. Stricklin;Helmut Sies

  • Oxidative stress in chronic venous leg ulcers

    Meinhard Wlaschek;Karin Scharffetter-Kochanek

  • Hydrogen peroxide (H2O2) increases the steady-state mRNA levels of collagenase/MMP-1 in human dermal fibroblasts.

    Peter Brenneisen;Karlis Briviba;Meinhard Wlaschek;Jutta Wenk

  • UV-induced oxidative stress and photoaging.

    J. Wenk;P. Brenneisen;C. Meewes;M. Wlaschek

  • TSG-6 Released from Intradermally Injected Mesenchymal Stem Cells Accelerates Wound Healing and Reduces Tissue Fibrosis in Murine Full-Thickness Skin Wounds

    Yu Qi;Dongsheng Jiang;Anca Sindrilaru;Agatha Stegemann

Frequent Co-Authors

Thomas Krieg
Thomas Krieg University of Cologne
Cord Sunderkötter
Cord Sunderkötter University of Münster
Thomas Krieg
Thomas Krieg University of Cambridge
Meinhard Wlaschek
Meinhard Wlaschek University of Ulm
Karlis Briviba
Karlis Briviba Heinrich Heine University Düsseldorf
Helmut Sies
Helmut Sies Heinrich Heine University Düsseldorf
Arthur L. Beaudet
Arthur L. Beaudet Baylor College of Medicine
Thomas Schwarz
Thomas Schwarz Boston Children's Hospital
Stephan Grabbe
Stephan Grabbe Johannes Gutenberg University of Mainz
Wilhelm Bloch
Wilhelm Bloch German Sport University Cologne

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