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Meinhard Wlaschek

Meinhard Wlaschek

D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
10728
World Ranking
17934
National Ranking
1234

Overview

Meinhard Wlaschek is affiliated with the University of Ulm in Germany and has contributed extensively to research in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work heavily intersects several subfields including Rehabilitation, Molecular Biology, Dermatology, Physiology, and Endocrine and Autonomic Systems.

Wlaschek's main research topics cover several key areas:

  • Wound Healing and Treatments
  • Skin Protection and Aging
  • Telomeres, Telomerase, and Senescence
  • Circadian rhythm and melatonin
  • Melanin and skin pigmentation
  • Mesenchymal stem cell research
  • Genetics, Aging, and Longevity in Model Organisms

The scientist has published significantly in journals such as the Journal of Investigative Dermatology, EMBO Reports, Cell Reports, Endocrine Reviews, and Nature Communications. Notable recent papers include:

  • Connective Tissue and Fibroblast Senescence in Skin Aging, 2021, Journal of Investigative Dermatology
  • TLR4-dependent shaping of the wound site by MSCs accelerates wound healing, 2020, EMBO Reports
  • Persistent JunB activation in fibroblasts disrupts stem cell niche interactions enforcing skin aging, 2021, Cell Reports
  • Angiogenin Released from ABCB5+ Stromal Precursors Improves Healing of Diabetic Wounds by Promoting Angiogenesis, 2021, Journal of Investigative Dermatology
  • Endocrine Controls of Skin Aging, 2025, Endocrine Reviews

Frequent co-authors collaborating with Wlaschek include:

  • Karin Scharffetter-Kochanek
  • Pallab Maity
  • Karmveer Singh
  • Albert Koroma
  • Linda Krug

Their scholarship reflects a research focus on the molecular mechanisms underpinning skin aging and wound healing, addressing cellular senescence, stem cell niche dynamics, and the role of immune signaling in tissue repair. The blend of clinical and molecular biology approaches is evident in the diversity of journals and the interdisciplinary subfields represented.

Best Publications

  • An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

    Anca Sindrilaru;Thorsten Peters;Stefan Wieschalka;Corina Baican

  • p16INK4A is a robust in vivo biomarker of cellular aging in human skin.

    Sigrun Ressler;Jirina Bartkova;Harald Niederegger;Jiri Bartek

  • UVA-induced autocrine stimulation of fibroblast-derived collagenase/MMP-1 by interrelated loops of interleukin-1 and interleukin-6.

    Meinhard Wlaschek;Gudrun Heinen;Arndt Poswig;Agatha Schwarz

  • Stable Overexpression of Manganese Superoxide Dismutase in Mitochondria Identifies Hydrogen Peroxide as a Major Oxidant in the AP-1-mediated Induction of Matrix-degrading Metalloprotease-1

    Jutta Wenk;Peter Brenneisen;Meinhard Wlaschek;Arndt Poswig

  • Activated macrophages are essential in a murine model for T cell–mediated chronic psoriasiform skin inflammation

    Honglin Wang;Thorsten Peters;Daniel Kess;Anca Sindrilaru

  • Central Role of Ferrous/Ferric Iron in the Ultraviolet B Irradiation-mediated Signaling Pathway Leading to Increased Interstitial Collagenase (Matrix-degrading Metalloprotease (MMP)-1) and Stromelysin-1 (MMP-3) mRNA Levels in Cultured Human Dermal Fibroblasts

    Peter Brenneisen;Jutta Wenk;L. Oliver Klotz;Meinhard Wlaschek

  • Oxidative stress in chronic venous leg ulcers

    Meinhard Wlaschek;Karin Scharffetter-Kochanek

  • Hydrogen peroxide (H2O2) increases the steady-state mRNA levels of collagenase/MMP-1 in human dermal fibroblasts.

    Peter Brenneisen;Karlis Briviba;Meinhard Wlaschek;Jutta Wenk

  • UV-induced oxidative stress and photoaging.

    J. Wenk;P. Brenneisen;C. Meewes;M. Wlaschek

  • TSG-6 Released from Intradermally Injected Mesenchymal Stem Cells Accelerates Wound Healing and Reduces Tissue Fibrosis in Murine Full-Thickness Skin Wounds

    Yu Qi;Dongsheng Jiang;Anca Sindrilaru;Agatha Stegemann

  • Chronological ageing and photoageing of the fibroblasts and the dermal connective tissue

    W. Ma;M. Wlaschek;I. Tantcheva-Poór;L. A. Schneider

  • UVA irradiation stimulates the synthesis of various matrix-metalloproteinases (MMPs) in cultured human fibroblasts.

    Gernot Herrmann;Meinhard Wlaschek;T. Sascha Lange;Klaus Prenzel

  • Singlet oxygen induces collagenase expression in human skin fibroblasts

    Karin Scharffetter-Kochanek;Meinhard Wlaschek;Karlis Briviba;Helmut Sies

  • UVA-induced autocrine stimulation of fibroblast-derived-collagenase by IL-6: a possible mechanism in dermal photodamage?

    Meinhard Wlaschek;Klaus Bolsen;Gernot Herrmann;Agatha Schwarz

  • Wound‐healing defect of CD18−/− mice due to a decrease in TGF‐β1 and myofibroblast differentiation

    Thorsten Peters;Anca Sindrilaru;Boris Hinz;Ralf Hinrichs

  • Singlet oxygen is an early intermediate in cytokine-dependent ultraviolet-A induction of interstitial collagenase in human dermal fibroblasts in vitro

    Meinhard Wlaschek;Jutta Wenk;Peter Brenneisen;Karlis Briviba

  • Suppression of Neutrophil-Mediated Tissue Damage-A Novel Skill of Mesenchymal Stem Cells

    Dongsheng Jiang;Jana Muschhammer;Yu Qi;Andrea Kügler

  • Connective Tissue and Fibroblast Senescence in Skin Aging.

    Meinhard Wlaschek;Pallab Maity;Evgenia Makrantonaki;Karin Scharffetter-Kochanek

  • Ultraviolet B Wavelength Dependence for the Regulation of Two Major Matrix‐Metalloproteinases and Their Inhibitor TIMP‐1 in Human Dermal Fibroblasts

    Peter Brenneisen;Jinsook Oh;Jinsook Oh;Meinhard Wlaschek;Jutta Wenk

  • Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation.

    Arndt Poswig;Jutta Wenk;Peter Brenneisen;Meinhard Wlaschek

Frequent Co-Authors

Stefan Kochanek
Stefan Kochanek University of Ulm
Karlis Briviba
Karlis Briviba Heinrich Heine University Düsseldorf
Hartmut Geiger
Hartmut Geiger University of Ulm
Wilhelm Bloch
Wilhelm Bloch German Sport University Cologne
Markus Huber-Lang
Markus Huber-Lang University of Ulm
Albert C. Ludolph
Albert C. Ludolph University of Ulm
Pidder Jansen-Dürr
Pidder Jansen-Dürr University of Innsbruck
Thomas Krieg
Thomas Krieg University of Cologne
Hayrettin Tumani
Hayrettin Tumani University of Ulm

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