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D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
22758
World Ranking
4307
National Ranking
102

Overview

Diana van Heemst is affiliated with the Leiden University Medical Center in the Netherlands. Their research spans multiple fields, predominantly focusing on medicine and biochemistry, genetics, and molecular biology.

Their work has a clear emphasis on endocrinology, diabetes, and metabolism, as well as genetics and molecular biology. Additional subfields include physiology and epidemiology.

The main research topics covered by Diana van Heemst include:

  • Genetic Associations and Epidemiology
  • Thyroid Disorders and Treatments
  • Metabolomics and Mass Spectrometry Studies
  • Growth Hormone and Insulin-like Growth Factors
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Frailty in Older Adults
  • Adipose Tissue and Metabolism

Notable frequent co-authors of van Heemst are:

  • Raymond Noordam
  • Ko Willems van Dijk
  • Simon P. Mooijaart
  • J. Wouter Jukema
  • P. Eline Slagboom

Publication venues where van Heemst has contributed most frequently include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • GeroScience
  • The Journal of Clinical Endocrinology & Metabolism
  • Atherosclerosis
  • Journal of the Endocrine Society

Recent papers authored or co-authored by van Heemst feature topics in the intersection of medicine, epidemiology, and molecular biology:

  • Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study (2021, Journal of Crohn's and Colitis)
  • Diet-Derived Circulating Antioxidants and Risk of Coronary Heart Disease (2021, Journal of the American College of Cardiology)
  • Association of Thyroid Dysfunction With Cognitive Function (2021, JAMA Internal Medicine)
  • Setting your clock: associations between timing of objective physical activity and cardiovascular disease risk in the general population (2022, European Journal of Preventive Cardiology)
  • Antioxidant Supplementation in Oxidative Stress-Related Diseases: What Have We Learned from Studies on Alpha-Tocopherol? (2022, Antioxidants)

Best Publications

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

    Z Dastani;Hivert M-F.;Hivert M-F.;N Timpson;Perry Jrb.;Perry Jrb.

  • Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

    J.L. Min;G. Hemani;E. Hannon;K.F. Dekkers

  • Ageing, age-related diseases and oxidative stress: What to do next?

    Jiao Luo;Kevin Mills;Saskia le Cessie;Raymond Noordam

  • Disease variants alter transcription factor levels and methylation of their binding sites.

    Marc Jan Bonder;René Luijk;Daria V Zhernakova;Matthijs Moed

  • Identification of context-dependent expression quantitative trait loci in whole blood

    Daria V Zhernakova;Patrick Deelen;Martijn Vermaat;Maarten van Iterson

  • Genetic and environmental influences interact with age and sex in shaping the human methylome

    Jenny van Dongen;Michel G. Nivard;Gonneke Willemsen;Jouke-Jan Hottenga

  • Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study.

    Carmen M. Martin-Ruiz;Jacobijn Gussekloo;Diana van Heemst;Thomas von Zglinicki

  • A meta-analysis of genome-wide association studies identifies multiple longevity genes

    Joris Deelen;Joris Deelen;Daniel S. Evans;Dan E. Arking;Niccolò Tesi;Niccolò Tesi

  • Genome-wide Association Study in 79,366 European-ancestry Individuals Informs the Genetic Architecture of 25-Hydroxyvitamin D Levels

    Xia Jiang;Xia Jiang;Paul F. O'Reilly;Hugues Aschard;Hugues Aschard;Yi Hsiang Hsu;Yi Hsiang Hsu

  • Reduced insulin/IGF-1 signalling and human longevity

    Diana Van Heemst;Marian Beekman;Simon P. Mooijaart;Bastiaan T. Heijmans

  • Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

    Joris Deelen;Marian Beekman;Hae-Won Uh;Quinta Helmer

  • Nonagenarian siblings and their offspring display lower risk of mortality and morbidity than sporadic nonagenarians: The Leiden Longevity Study.

    Rudi G.J. Westendorp;Diana Van Heemst;Maarten P. Rozing;Marijke Frölich

  • Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution.

    Maarten van Iterson;Erik W van Zwet;Bastiaan T Heijmans;Peter a.C ’t Hoen

  • Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

    Joris Deelen;Marian Beekman;Hae-Won Uh;Linda Broer

  • A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

    Joris Deelen;Joris Deelen;Johannes Kettunen;Krista Fischer;Ashley van der Spek

  • The number of p16INK4a positive cells in human skin reflects biological age

    Mariëtte E.C. Waaijer;William E. Parish;Barbara H. Strongitharm;Diana van Heemst

  • Variation in the human TP53 gene affects old age survival and cancer mortality.

    Diana van Heemst;Simon P. Mooijaart;Marian Beekman;Jeroen Schreuder

  • A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function

    Eleonora Porcu;Marco Medici;Giorgio Pistis;Claudia B Volpato

Frequent Co-Authors

P. Eline Slagboom
P. Eline Slagboom Leiden University Medical Center
Rudi G. J. Westendorp
Rudi G. J. Westendorp University of Copenhagen
Marian Beekman
Marian Beekman Leiden University Medical Center
Joris Deelen
Joris Deelen Max Planck Society
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Anton J. M. de Craen
Anton J. M. de Craen Leiden University Medical Center
J. Wouter Jukema
J. Wouter Jukema Leiden University Medical Center
Bruce M. Psaty
Bruce M. Psaty University of Washington
Dennis O. Mook-Kanamori
Dennis O. Mook-Kanamori Leiden University Medical Center
Stella Trompet
Stella Trompet Leiden University Medical Center

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