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Biology and Biochemistry

D-Index
70
Citations
24654
World Ranking
6877
National Ranking
499

Overview

Joris Deelen is affiliated with the Max Planck Society in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant work also conducted in medicine. Within these broad fields, their subfields of study include molecular biology, physiology, genetics, aging, and pediatric health.

Their scientific contributions span several main topics:

  • Genetics, Aging, and Longevity in Model Organisms
  • Epigenetics and DNA Methylation
  • Diet and Metabolism Studies
  • Genetic Associations and Epidemiology
  • Metabolomics and Mass Spectrometry Studies
  • Birth, Development, and Health
  • Adipose Tissue and Metabolism

Joris Deelen has published extensively in various scientific venues. The most frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • GeroScience
  • EBioMedicine
  • UNC Libraries

The scientist's recent published papers exemplify their research focus and have accrued notable citations. Representative recent works are:

  • Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length, 2020, The American Journal of Human Genetics
  • Multivariate genomic scan implicates novel loci and haem metabolism in human ageing, 2020, Nature Communications
  • Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases, 2020, Science Advances
  • Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification, 2023, Nature Genetics
  • Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework, 2020, Mechanisms of Ageing and Development

Collaboration is a significant aspect of Joris Deelen's work. Frequent co-authors include:

  • P. Eline Slagboom
  • Marian Beekman
  • Dorret I. Boomsma
  • Cornelia M. van Duijn
  • Erik B. van den Akker

Best Publications

  • Defining the role of common variation in the genomic and biological architecture of adult human height

    Andrew R. Wood;Tonu Esko;Jian Yang;Sailaja Vedantam

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Facing up to the global challenges of ageing.

    Linda Partridge;Joris Deelen;Joris Deelen;P. Eline Slagboom;P. Eline Slagboom

  • Identification of seven loci affecting mean telomere length and their association with disease

    Veryan Codd;Christopher P Nelson;Eva Albrecht;Massimo Mangino

  • Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

    Johannes Kettunen;Ayşe Demirkan;Ayşe Demirkan;Peter Würtz;Harmen H M Draisma

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Helen R Warren;Evangelos Evangelou;Evangelos Evangelou;Claudia P Cabrera;He Gao

  • Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect

    Linda Broer;Veryan Codd;Veryan Codd;Dale R Nyholt;Joris Deelen

  • Disease variants alter transcription factor levels and methylation of their binding sites.

    Marc Jan Bonder;René Luijk;Daria V Zhernakova;Matthijs Moed

  • Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

    S Ligthart;A Vaez;U Võsa;M G Stathopoulou

  • Identification of context-dependent expression quantitative trait loci in whole blood

    Daria V Zhernakova;Patrick Deelen;Martijn Vermaat;Maarten van Iterson

  • Genetic and environmental influences interact with age and sex in shaping the human methylome

    Jenny van Dongen;Michel G. Nivard;Gonneke Willemsen;Jouke-Jan Hottenga

  • A meta-analysis of genome-wide association studies identifies multiple longevity genes

    Joris Deelen;Joris Deelen;Daniel S. Evans;Dan E. Arking;Niccolò Tesi;Niccolò Tesi

  • The impact of low-frequency and rare variants on lipid levels.

    Ida Surakka;Ida Surakka;Momoko Horikoshi;Reedik Mägi;Antti-Pekka Sarin;Antti-Pekka Sarin

  • Genome-wide Association Study in 79,366 European-ancestry Individuals Informs the Genetic Architecture of 25-Hydroxyvitamin D Levels

    Xia Jiang;Xia Jiang;Paul F. O'Reilly;Hugues Aschard;Hugues Aschard;Yi Hsiang Hsu;Yi Hsiang Hsu

  • Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

    Joris Deelen;Marian Beekman;Hae-Won Uh;Quinta Helmer

  • Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution.

    Maarten van Iterson;Erik W van Zwet;Bastiaan T Heijmans;Peter a.C ’t Hoen

  • GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy

    Linda Broer;Linda Broer;Aron S. Buchman;Joris Deelen;Daniel S. Evans

  • Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age

    Joris Deelen;Marian Beekman;Hae-Won Uh;Linda Broer

  • A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

    Joris Deelen;Joris Deelen;Johannes Kettunen;Krista Fischer;Ashley van der Spek

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Marian Beekman
Marian Beekman Leiden University Medical Center
P. Eline Slagboom
P. Eline Slagboom Leiden University Medical Center
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Diana van Heemst
Diana van Heemst Leiden University Medical Center
Albert Hofman
Albert Hofman Harvard University
Markus Perola
Markus Perola Finnish Institute for Health and Welfare
Dorret I. Boomsma
Dorret I. Boomsma Vrije Universiteit Amsterdam
Gonneke Willemsen
Gonneke Willemsen Vrije Universiteit Amsterdam
Olli T. Raitakari
Olli T. Raitakari Turku University Hospital
Stella Trompet
Stella Trompet Leiden University Medical Center

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