Kenneth T. Douglas

Overview

Best Publications

• Quantum dot FRET biosensors that respond to pH, to proteolytic or nucleolytic cleavage, to DNA synthesis, or to a multiplexing combination.

  Miho Suzuki;Yuzuru Husimi;Hirokazu Komatsu;Koji Suzuki

  292
  Citations

• Self-Assembly of Heterobimetallic d-f Hybrid Complexes: Sensitization of Lanthanide Luminescence by d-Block Metal-to-Ligand Charge-Transfer Excited States

  Simon J. A. Pope;Benjamin J. Coe;Stephen Faulkner;Elena V. Bichenkova

  245
  Citations

• Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.

  Cecil Chan;Hong Yin;Jacqui Garforth;James H. McKie

  195
  Citations

• Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures.

  T J Benson;J H McKie;J Garforth;A Borges

  193
  Citations

• Improved efficiency and selectivity in peptide synthesis: Use of triethylsilane as a carbocation scavenger in deprotection of t-butyl esters and t-butoxycarbonyl-protected sites

  Anita Mehta;Rabih Jaouhari;Timothy J. Benson;Kenneth T. Douglas

  168
  Citations

• Minor-groove recognition of the self-complementary duplex d(CGCGAATTCGCG)2 by hoechst 33258 : a high-field NMR study

  John A. Parkinson;Jill Barber;Kenneth T. Douglas;John Rosamond

  166
  Citations

• Transfer of biologically derived nanometer-scale patterns to smooth substrates.

  Kenneth Douglas;Genevieve Devaud;Noel A. Clark

  157
  Citations

• Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase

  Nikita A. Kuznetsov;Vladimir V. Koval;Dmitry O. Zharkov;Georgy A. Nevinsky

  141
  Citations

• Antitrypanosomal, Antileishmanial, and Antimalarial Activities of Quaternary Arylalkylammonium 2-Amino-4-Chlorophenyl Phenyl Sulfides, a New Class of Trypanothione Reductase Inhibitor, and of N-Acyl Derivatives of 2-Amino-4-Chlorophenyl Phenyl Sulfide

  Seheli Parveen;Mohammed O F Khan;Susan E. Austin;Simon L. Croft

  127
  Citations

• Chemical cleavage of plasmid DNA by glutathione in the presence of Cu(II) ions. The Cu(II)-thiol system for DNA strand scission.

  C J Reed;K T Douglas

  127
  Citations

• Use of an additional hydrophobic binding site, the Z site, in the rational drug design of a new class of stronger trypanothione reductase inhibitor, quaternary alkylammonium phenothiazines

  M. O. F. Khan;S. E. Austin;C. Chan;Hong Yin

  112
  Citations

• Nanometer molecular lithography

  Kenneth Douglas;Noel A. Clark;Kenneth J. Rothschild

  109
  Citations

• Thallium in biochemistry.

  Kenneth T. Douglas;Marlene A. Bunni;Swati R. Baindur

  105
  Citations

• Rational drug design approach for overcoming drug resistance: Application to pyrimethamine resistance in malaria

  James H. McKie;Kenneth T. Douglas;Cecil Chan;Simon A. Roser

  101
  Citations

• Evidence for gene duplication forming similar binding folds for NAD(P)H and FAD in pyridine nucleotide-dependent flavoenzymes.

  James H. McKie;Kenneth T. Douglas

  95
  Citations

• Kinetic Conformational Analysis of Human 8-Oxoguanine-DNA Glycosylase

  Nikita A. Kuznetsov;Nikita A. Kuznetsov;Vladimir V. Koval;Vladimir V. Koval;Georgy A. Nevinsky;Georgy A. Nevinsky;Kenneth T. Douglas

  90
  Citations

• VI. Applications of S-layers

  Uwe B Sleytr;Hagan Bayley;Margit Sára;Andreas Breitwieser

  88
  Citations

• Stopped-flow kinetic studies of the interaction between Escherichia coli Fpg protein and DNA substrates

  Olga S. Fedorova;Georgy A. Nevinsky;Vladimir V. Koval;Alexander A. Ishchenko

  82
  Citations

• Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening

  João Neres;Mark L. Brewer;Laura Ratier;Horacio Botti

  80
  Citations

• Single-strand cleavage of DNA by Cu(II) and thiols: a powerful chemical DNA-cleaving system.

  Celia J. Reed;Kenneth T. Douglas

  75
  Citations