Ian J. Stratford

Overview

Best Publications

• Guidelines for the welfare and use of animals in cancer research

  P Workman;E O Aboagye;F Balkwill;A Balmain

  1567
  Citations

• Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

  P H Maxwell;G U Dachs;J M Gleadle;L G Nicholls

  1402
  Citations

• Acquired Resistance to Fractionated Radiotherapy Can Be Overcome by Concurrent PD-L1 Blockade

  Simon J. Dovedi;Amy L. Adlard;Grazyna Lipowska-Bhalla;Conor McKenna

  1283
  Citations

• Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix.

  Juliette A. Loncaster;Adrian L. Harris;Susan E. Davidson;John P. Logue

  717
  Citations

• Anticancer Chemosensitization and Radiosensitization by the Novel Poly(ADP-ribose) Polymerase-1 Inhibitor AG14361

  Christopher R. Calabrese;Robert Almassy;Stephanie Barton;Michael A. Batey

  588
  Citations

• Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance.

  Janine T Erler;Christopher Cawthorne;Kaye J Williams;Marianne Koritzinsky

  511
  Citations

• Electron-affinic sensitization. VII. A correlation between structures, one-electron reduction potentials, and efficiencies of nitroimidazoles as hypoxic cell radiosensitizers.

  G. E. Adams;I. R. Flockhart;C. E. Smithen;I. J. Stratford

  489
  Citations

• Targeting gene expression to hypoxic tumor cells.

  G.U Dachs;Aa.V Patterson;Aa.V Patterson;J.D Firth;P.J Ratcliffe

  458
  Citations

• Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix.

  R Airley;Juliette A Loncaster;Susan E Davidson;Michael Bromley

  434
  Citations

• Clinical development of new drug-radiotherapy combinations

  Ricky A Sharma;Ruth Plummer;Julie K Stock;Tessa A Greenhalgh

  331
  Citations

• Structure-activity relationships in the development of hypoxic cell radiosensitizers. I. Sensitization efficiency

  G.E. Adams;E.D. Clarke;I.R. Flockhart;R.S. Jacobs

  318
  Citations

• Targeting gene therapy to cancer: a review.

  G U Dachs;G J Dougherty;I J Stratford;D J Chaplin

  312
  Citations

• GLUT-1 and CAIX as intrinsic markers of hypoxia in carcinoma of the cervix: relationship to pimonidazole binding.

  Rachel E. Airley;Juliette Loncaster;James A. Raleigh;Adrian L. Harris

  293
  Citations

• HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells.

  P J Maxwell;R Gallagher;A Seaton;C Wilson

  275
  Citations

• The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo.

  Leigh Griffiths;Gabi U. Dachs;Roy Bicknell;Adrian L. Harris

  272
  Citations

• Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice.

  Melissa K. Friswell;Helen Gika;Helen Gika;Ian J. Stratford;Georgios Theodoridis;Georgios Theodoridis

  264
  Citations

• ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model.

  Kaye J. Williams;B. A. Telfer;I. J. Stratford;S. R. Wedge

  259
  Citations

• Tumour oxygenation levels correlate with dynamic contrast-enhanced magnetic resonance imaging parameters in carcinoma of the cervix.

  Rachel A Cooper;Bernadette M Carrington;Juliette A Loncaster;Susan M Todd

  251
  Citations

• Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy.

  Jonathan D. Silk;Ian F. Hermans;Uzi Gileadi;Tsung Wen Chong

  219
  Citations

• Inhibition of PARP-1 by Olaparib (AZD2281) Increases the Radiosensitivity of a Lung Tumor Xenograft

  Joana M. Senra;Brian A Telfer;Kim E Cherry;Cian M McCrudden

  215
  Citations

• Radiation sensitization and chemopotentiation: Rsu 1069, a compound more efficient than misonidazole in vitro and in vivo

  G E Adams;I Ahmed;P W Sheldon;I J Stratford

  209
  Citations