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Christopher W. Pugh

Christopher W. Pugh

University of Oxford
United Kingdom

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
54280
World Ranking
3055
National Ranking
230

Christopher W. Pugh publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christopher W. Pugh sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 186 publications — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christopher W. Pugh D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christopher W. Pugh sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 85 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Christopher W. Pugh is affiliated with the University of Oxford in the United Kingdom. The main fields of their research include Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields such as Molecular Biology, Cancer Research, Immunology, Genetics, and Cardiology and Cardiovascular Medicine.

Their work encompasses various main topics, including Cancer, Hypoxia, and Metabolism; High Altitude and Hypoxia; Immune cells in cancer; Congenital heart defects research; Epigenetics and DNA Methylation; Single-cell and spatial transcriptomics; and Immune Response and Inflammation.

Recent publications showcase the diversity and focus of their research. These include:

  • Multiparameter persistent homology landscapes identify immune cell spatial patterns in tumors, 2021, Proceedings of the National Academy of Sciences
  • Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation, 2022, Nature Immunology
  • Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases, 2023, Genome Medicine
  • Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control, 2020, Journal of Clinical Investigation
  • Combining multiple spatial statistics enhances the description of immune cell localisation within tumours, 2020, Scientific Reports

Christopher W. Pugh frequently publishes in venues such as Cancer Research, Nature Communications, Nature Immunology, Scientific Reports, and Wellcome Open Research. Their contributions include five publications in Cancer Research, three in Nature Communications, two each in Nature Immunology and Scientific Reports, and two in Wellcome Open Research.

They often collaborate with other researchers in the field. Frequent co-authors include:

  • Peter J. Ratcliffe (12 collaborations)
  • Joanna D.C.C. Lima (8 collaborations)
  • Julie Adam (8 collaborations)
  • Samvid Kurlekar (7 collaborations)
  • David R. Mole (7 collaborations)

Best Publications

  • Targeting of HIF-alpha to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation

    Panu Jaakkola;David R. Mole;Ya-Min Tian;Michael I. Wilson

  • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

    Patrick H. Maxwell;Michael S. Wiesener;Gin-Wen Chang;Steven C. Clifford

  • C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.

    Andrew C.R. Epstein;Jonathan M. Gleadle;Luke A. McNeill;Kirsty S. Hewitson

  • Regulation of angiogenesis by hypoxia: role of the HIF system.

    Christopher W Pugh;Peter J Ratcliffe

  • The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages

    Katherine L. Talks;Helen Turley;Kevin C. Gatter;Patrick H. Maxwell

  • Hypoxia-inducible Expression of Tumor-associated Carbonic Anhydrases

    Charles C. Wykoff;Nigel J. P. Beasley;Peter H. Watson;Kevin J. Turner

  • Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

    P H Maxwell;G U Dachs;J M Gleadle;L G Nicholls

  • Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.

    Matthew E. Cockman;Norma Masson;David R. Mole;Panu Jaakkola

  • Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation

    Norma Masson;Carsten Willam;Patrick H. Maxwell;Christopher W. Pugh

  • Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor *

    Rebecca J. Appelhoff;Ya-Min Tian;Raju R. Raval;Helen Turley

  • Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma

    Raju R. Raval;Kah Weng Lau;Maxine G. B. Tran;Heidi M. Sowter

  • Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

    Michael S Wiesener;Jan Steffen Jürgensen;Christian Rosenberger;Charlotte K Scholze

  • Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family

    Kirsty S. Hewitson;Luke A. McNeill;Madeline V. Riordan;Ya-Min Tian

  • Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.

    Wai-Ching Hon;Michael I. Wilson;Karl Harlos;Timothy D. W. Claridge

  • Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.

    M.S. Wiesener;H. Turley;H. Turley;William Allen;William Allen;C. Willam;C. Willam

  • High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

    Johannes Schödel;Spyros Oikonomopoulos;Jiannis Ragoussis;Christopher W. Pugh

  • Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit.

    Christopher W. Pugh;John F. O'Rourke;Masaya Nagao;Jonathan M. Gleadle

  • Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.

    J D Firth;B L Ebert;C W Pugh;P J Ratcliffe

  • Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

    Julie Adam;Emine Hatipoglu;Linda O'Flaherty;Nicola Ternette

  • Activation of the HIF pathway in cancer

    Patrick H Maxwell;Christopher W Pugh;Peter J Ratcliffe

Frequent Co-Authors

Peter J. Ratcliffe
Peter J. Ratcliffe The Francis Crick Institute
Patrick H. Maxwell
Patrick H. Maxwell University of Cambridge
Christopher J. Schofield
Christopher J. Schofield University of Oxford
Benedikt M. Kessler
Benedikt M. Kessler University of Oxford
Rafael Perera
Rafael Perera University of Oxford
Helen M. Colhoun
Helen M. Colhoun University of Edinburgh
Lionel Tarassenko
Lionel Tarassenko University of Oxford
Philip Clarke
Philip Clarke University of Oxford
adrian l harris
adrian l harris University of Oxford
Peter Carmeliet
Peter Carmeliet KU Leuven

External Links

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Best Scientists Citing Christopher W. Pugh

adrian l harris

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Gregg L. Semenza

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Peter J. Ratcliffe

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The Francis Crick Institute

Publications: 147

William G. Kaelin

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Harvard University

Publications: 139

Claudiu T. Supuran

Claudiu T. Supuran

University of Florence

Publications: 120

M. Celeste Simon

M. Celeste Simon

University of Pennsylvania

Publications: 119

Randall S. Johnson

Randall S. Johnson

University of Cambridge

Publications: 117

Patrick H. Maxwell

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University of Cambridge

Publications: 98

Amato J. Giaccia

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Stanford University

Publications: 96

Peter Carmeliet

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KU Leuven

Publications: 83

Silvia Pastorekova

Silvia Pastorekova

Slovak Academy of Sciences

Publications: 78

W. Marston Linehan

W. Marston Linehan

National Institutes of Health

Publications: 77

Max Gassmann

Max Gassmann

University of Zurich

Publications: 77

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Roland H. Wenger

University of Zurich

Publications: 74

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Jaromir Pastorek

Slovak Academy of Sciences

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