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Biology and Biochemistry

D-Index
63
Citations
12129
World Ranking
10381
National Ranking
4507

Overview

Ted S. Acott is affiliated with Oregon Health & Science University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on ophthalmology and cellular mechanisms relevant to eye health and diseases.

Acott's work engages deeply with subjects such as glaucoma and retinal disorders, corneal surgery and disorders, ophthalmology and eye disorders, proteoglycans and glycosaminoglycans research, cellular mechanics and interactions, retinal diseases and treatments, as well as Hippo pathway signaling and YAP/TAZ.

Frequent publication venues for their research include:

  • Computer Methods and Programs in Biomedicine
  • Acta Biomaterialia
  • Experimental Eye Research
  • Investigative Ophthalmology & Visual Science
  • Bioengineering

Several co-authors have collaborated extensively with Acott, including:

  • Mary J. Kelley
  • Alireza Karimi
  • Reza Razaghi
  • Janice A. Vranka
  • Vijay Krishna Raghunathan

Among their recent research papers are:

  • "Normal and glaucomatous outflow regulation" (2020, Progress in Retinal and Eye Research)
  • "Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms" (2022, Investigative Ophthalmology & Visual Science)
  • "Biomechanics of human trabecular meshwork in healthy and glaucoma eyes via dynamic Schlemm's canal pressurization" (2022, Computer Methods and Programs in Biomedicine)
  • "Morphological and biomechanical analyses of the human healthy and glaucomatous aqueous outflow pathway: Imaging-to-modeling" (2023, Computer Methods and Programs in Biomedicine)
  • "The Effect of Intraocular Pressure Load Boundary on the Biomechanics of the Human Conventional Aqueous Outflow Pathway" (2022, Bioengineering)

The scientist's research encompasses detailed exploration into the physiological and biomechanical aspects of ocular tissues, particularly related to aqueous humor outflow and the trabecular meshwork, critical elements in understanding glaucoma mechanisms.

Acott's subfields of study include ophthalmology, radiology, nuclear medicine and imaging, cell biology, molecular biology, and pathology and forensic medicine. This multidisciplinary approach supports research into the molecular and cellular bases of eye diseases as well as advanced imaging and biomechanical modeling techniques.

Best Publications

  • Extracellular matrix in the trabecular meshwork.

    Ted S. Acott;Mary J. Kelley

  • Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif.

    Daniel W. Carr;Renata E. Stofko-Hahn;Iain D C Fraser;Sarah M. Bishop

  • Effect of matrix metalloproteinases activity on outflow in perfused human organ culture.

    J. M. B. Bradley;J. Vranka;C. M. Colvis;D. M. Conger

  • Elastic modulus determination of normal and glaucomatous human trabecular meshwork.

    Tingrui Pan;Yuzhe Ding;Christopher M. Reilly

  • Extracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucoma.

    Janice A. Vranka;Mary J. Kelley;Ted S. Acott;Kate E. Keller

  • Current understanding of conventional outflow dysfunction in glaucoma.

    W. Daniel Stamer;Ted S. Acott

  • Age-related macular degeneration: Clinical features in a large family and linkage to chromosome 1q

    Michael L. Klein;Dennis W. Schultz;Al Edwards;Tara C. Matise

  • Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

    Kate E. Keller;Sanjoy K. Bhattacharya;Theresa Borrás;Thomas M. Brunner

  • Expression of matrix metalloproteinases and inhibitor by human trabecular meshwork.

    J P Alexander;J R Samples;E M Van Buskirk;T S Acott

  • Age-Related Macular Degeneration—a Genome Scan in Extended Families

    Jacek Majewski;Dennis W. Schultz;Richard G. Weleber;Mitchell B. Schain

  • GLC1F, a new primary open-angle glaucoma locus, maps to 7q35-q36.

    Mary K. Wirtz;John R. Samples;Kristal Rust;Jennifer Lie

  • Extracellular Matrix Turnover and Outflow Resistance

    Kate E. Keller;Mini Aga;John M. Bradley;Mary J. Kelley

  • Inhibition of bovine spermatozoa by caudal epididymal fluid: II. Interaction of pH and a quiescence factor.

    Ted S. Acott;Daniel W. Carr

  • Analysis of the ARMD1 locus: evidence that a mutation in HEMICENTIN-1 is associated with age-related macular degeneration in a large family

    Dennis W. Schultz;Michael L. Klein;Andrea J. Humpert;Christina W. Luzier

  • Mediation of laser trabeculoplasty-induced matrix metalloproteinase expression by IL-1β and TNFα

    John M.B. Bradley;Ann Marie Anderssohn;Christine M. Colvis;Dorothy E. Parshley

  • Argon laser trabeculoplasty. Studies of mechanism of action.

    E. Michael Van Buskirk;Valerie Pond;Robert C. Rosenquist;Ted S. Acott

  • Effects of pH, lactate, and viscoelastic drag on sperm motility: a species comparison.

    Daniel W. Carr;Marion C. Usselman;Marion C. Usselman;Ted S. Acott

  • Trabecular repopulation by anterior trabecular meshwork cells after laser trabeculoplasty.

    John R. Samples;John M.B. Bradley;David R. Bacon;Stephen S. Bylsma

  • Changes in gene expression by trabecular meshwork cells in response to mechanical stretching

    Vasavi Vittal;Anastasia Rose;Kate E. Gregory;Mary J. Kelley

  • Intraocular pressure homeostasis: maintaining balance in a high-pressure environment

    Ted S. Acott;Mary J. Kelley;Kate E. Keller;Janice A. Vranka

Frequent Co-Authors

Richard G. Weleber
Richard G. Weleber Oregon Health & Science University
Daniel W. Carr
Daniel W. Carr Oregon Health & Science University
Jurg Ott
Jurg Ott Rockefeller University
Jacek Majewski
Jacek Majewski McGill University
Patricia L. Kramer
Patricia L. Kramer Oregon Health & Science University
Paul Russell
Paul Russell Scripps Research Institute
C. Ross Ethier
C. Ross Ethier Georgia Institute of Technology
Christopher J. Murphy
Christopher J. Murphy University of California, Davis
Tara C. Matise
Tara C. Matise Rutgers, The State University of New Jersey
Tingrui Pan
Tingrui Pan University of California, Davis

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