D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 7,685 154 World Ranking 12249 National Ranking 5216

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

David L. Epstein mainly investigates Trabecular meshwork, Cell biology, Glaucoma, Cell culture and Anatomy. His Trabecular meshwork study incorporates themes from Biophysics, Downregulation and upregulation, Biochemistry, Cell junction and Cytoskeleton. In his research on the topic of Cytoskeleton, Myosin and Focal adhesion is strongly related with Actin.

Cell biology connects with themes related to Pathology in his study. David L. Epstein interconnects Intraocular pressure and Comorbidity in the investigation of issues within Glaucoma. His research integrates issues of Cell and Matrix in his study of Anatomy.

His most cited work include:

  • Modulation of Aqueous Humor Outflow Facility by the Rho Kinase–Specific Inhibitor Y-27632 (369 citations)
  • Cytoskeletal involvement in the regulation of aqueous humor outflow. (205 citations)
  • Carbonic Anhydrase Inhibitor Side Effects: Serum Chemical Analysis (164 citations)

What are the main themes of his work throughout his whole career to date?

Trabecular meshwork, Cell biology, Glaucoma, Ophthalmology and Anatomy are his primary areas of study. His Trabecular meshwork research includes elements of Cell culture, Endocrinology, Biophysics, Internal medicine and Cytoskeleton. His work deals with themes such as Molecular biology and Cell type, which intersect with Cell culture.

His Cytoskeleton research is multidisciplinary, relying on both Myosin and Focal adhesion. Much of his study explores Cell biology relationship to Oxidative stress. David L. Epstein usually deals with Glaucoma and limits it to topics linked to Intraocular pressure and Anesthesia and Cornea.

He most often published in these fields:

  • Trabecular meshwork (57.42%)
  • Cell biology (39.23%)
  • Glaucoma (22.97%)

What were the highlights of his more recent work (between 2009-2019)?

  • Trabecular meshwork (57.42%)
  • Cell biology (39.23%)
  • Ophthalmology (18.18%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Trabecular meshwork, Cell biology, Ophthalmology, Downregulation and upregulation and Glaucoma. David L. Epstein has included themes like Internal medicine, Cytoskeleton, Chronic oxidative stress and Anatomy in his Trabecular meshwork study. His work on Extracellular matrix as part of general Cell biology study is frequently linked to Dicer, therefore connecting diverse disciplines of science.

His work in Ophthalmology covers topics such as Perfusion which are related to areas like Aqueous humor outflow, Surgery, Suidae and Outflow resistance. His Downregulation and upregulation research focuses on subjects like Senescence, which are linked to Cell type and Cell culture. His research in Glaucoma intersects with topics in Lens epithelial cell, Cathepsin D and Lens capsule.

Between 2009 and 2019, his most popular works were:

  • Role of miR-204 in the Regulation of Apoptosis, Endoplasmic Reticulum Stress Response, and Inflammation in Human Trabecular Meshwork Cells (91 citations)
  • Cross-talk between miR-29 and transforming growth factor-betas in trabecular meshwork cells. (65 citations)
  • Emerging trabecular outflow drugs. (50 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Trabecular meshwork, Cell biology, Ophthalmology, Glaucoma and Anatomy. He undertakes interdisciplinary study in the fields of Trabecular meshwork and Outflow through his research. His Cell biology study combines topics in areas such as Endocrinology, Downregulation and upregulation, Molecular biology, Internal medicine and Regulation of gene expression.

His Ophthalmology research is multidisciplinary, incorporating elements of Suidae and Perfusion. His work carried out in the field of Glaucoma brings together such families of science as Pharmacology and Rho kinase inhibitor. The concepts of his Anatomy study are interwoven with issues in Lens epithelial cell, Lens, Lens capsule, Pseudoexfoliation syndrome and Pseudoexfoliation glaucoma.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Modulation of Aqueous Humor Outflow Facility by the Rho Kinase–Specific Inhibitor Y-27632

Rao Pv;Deng Pf;Kumar J;Epstein Dl.
Investigative Ophthalmology & Visual Science (2001)

463 Citations

Cytoskeletal involvement in the regulation of aqueous humor outflow.

Baohe Tian;Benjamin Geiger;David L. Epstein;Paul L. Kaufman.
Investigative Ophthalmology & Visual Science (2000)

322 Citations

Carbonic Anhydrase Inhibitor Side Effects: Serum Chemical Analysis

David L. Epstein;W. Morton Grant.
Archives of Ophthalmology (1977)

250 Citations

Alterations in microRNA expression in stress-induced cellular senescence

Guorong Li;Coralia Luna;Jianming Qiu;David L. Epstein.
Mechanisms of Ageing and Development (2009)

245 Citations

Chandler and Grant's Glaucoma

Paul A. Chandler;W. Morton Grant;David L. Epstein;R. Rand Allingham.
(1986)

220 Citations

Rho GTPase/Rho Kinase Inhibition as a Novel Target for the Treatment of Glaucoma

Vasantha P Rao;David L Epstein.
BioDrugs (2007)

208 Citations

Modulation of Myocilin/TIGR Expression in Human Trabecular Meshwork

Ernst R. Tamm;Paul Russell;David L. Epstein;Douglas H. Johnson.
Investigative Ophthalmology & Visual Science (1999)

206 Citations

Glucocorticoids regulate transendothelial fluid flow resistance and formation of intercellular junctions.

Johnnie L. Underwood;Collin G. Murphy;Janet Chen;Linda Franse-Carman.
American Journal of Physiology-cell Physiology (1999)

206 Citations

Role of miR-29b on the regulation of the extracellular matrix in human trabecular meshwork cells under chronic oxidative stress.

Coralia Luna;Guorong Li;Jianmimg Qiu;David L. Epstein.
Molecular Vision (2009)

195 Citations

Acto-myosin drug effects and aqueous outflow function.

D L Epstein;L L Rowlette;B C Roberts.
Investigative Ophthalmology & Visual Science (1999)

183 Citations

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