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Neuroscience

D-Index
51
Citations
11252
World Ranking
5474
National Ranking
2436

Overview

Roman J. Giger is affiliated with the University of Michigan-Ann Arbor in the United States. Their research primarily focuses on the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology. Within these fields, Giger's work spans subfields such as Cellular and Molecular Neuroscience, Molecular Biology, Developmental Neuroscience, Neurology, and Genetics.

The scientist has contributed notably to several key topics within neuroscience including:

  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Axon Guidance and Neuronal Signaling
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Genetics and Neurodevelopmental Disorders
  • Signaling Pathways in Disease
  • Retinal Development and Disorders

Roman J. Giger has published extensively, with frequent contributions to several scientific journals and venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Cell Reports
  • Annals of Neurology
  • Scientific Reports

Among recent significant papers authored or co-authored by Giger are:

  • A new neutrophil subset promotes CNS neuron survival and axon regeneration, 2020, Nature Immunology
  • Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement, 2020, eLife
  • Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome, 2020, Annals of Neurology
  • The injured sciatic nerve atlas (iSNAT), insights into the cellular and molecular basis of neural tissue degeneration and regeneration, 2022, eLife
  • Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium, 2023, Molecular Neurodegeneration

Frequent co-authors in Giger's research collaborations include:

  • Xiaofeng Zhao
  • Rafi Kohen
  • Ashley L. Kalinski
  • Craig Johnson
  • Daniel H. Geschwind

Best Publications

  • Neuropilin is a semaphorin III receptor.

    Alex L. Kolodkin;Dorothy V. Levengood;Erica G. Rowe;Yu Tzu Tai

  • Neuropilin-2 Is Required In Vivo for Selective Axon Guidance Responses to Secreted Semaphorins

    Roman J. Giger;Jean François Cloutier;Amar Sahay;Rabinder K. Prinjha

  • NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans

    Travis L. Dickendesher;Katherine T. Baldwin;Yevgeniya A. Mironova;Yoshiki Koriyama

  • Semaphorin 5A is a bifunctional axon guidance cue regulated by heparan and chondroitin sulfate proteoglycans.

    David B. Kantor;Onanong Chivatakarn;Katherine L. Peer;Stephen F. Oster

  • Neuropilin-2 Is a Receptor for Semaphorin IV Insight into the Structural Basis of Receptor Function and Specificity

    Roman J Giger;Erica Rowe Urquhart;Susan K.H Gillespie;Dorothy V Levengood

  • Guidance Molecules in Axon Regeneration

    Roman J. Giger;Edmund R. Hollis;Mark H. Tuszynski

  • An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke

    Songlin Li;Justine J Overman;Diana Katsman;Serguei V Kozlov

  • Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS.

    R.J. Pasterkamp;R.J. Giger;M.J. Ruitenberg;A.J.G.D. Holtmaat

  • Patterning of Cortical Efferent Projections by Semaphorin-Neuropilin Interactions

    Franck Polleux;Roman J. Giger;David D. Ginty;Alex L. Kolodkin

  • The Nogo-66 Receptor Homolog NgR2 Is a Sialic Acid-Dependent Receptor Selective for Myelin-Associated Glycoprotein

    Karthik Venkatesh;Onanong Chivatakarn;Hakjoo Lee;Pushkar S. Joshi

  • Semaphorin function in neural plasticity and disease

    R Jeroen Pasterkamp;Roman J Giger

  • A new neutrophil subset promotes CNS neuron survival and axon regeneration

    Andrew R. Sas;Andrew R. Sas;Andrew R. Sas;Kevin S. Carbajal;Andrew D. Jerome;Andrew D. Jerome;Rajasree Menon

  • Anatomy of rat semaphorin III collapsin‐1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis

    Roman J. Giger;David P. Wolfer;Gerard M.J. De Wit;Joost Verhaagen

  • Synaptic function for the Nogo-66 receptor NgR1: regulation of dendritic spine morphology and activity-dependent synaptic strength.

    Hakjoo Lee;Stephen J. Raiker;Karthik Venkatesh;Karthik Venkatesh;Rebecca Geary

  • Class 5 transmembrane semaphorins control selective mammalian retinal lamination and function

    Ryota L. Matsuoka;Onanong Chivatakarn;Tudor C. Badea;Ivy S. Samuels;Ivy S. Samuels

  • Neuroinflammation triggered by β-glucan/dectin-1 signaling enables CNS axon regeneration

    Katherine T. Baldwin;Kevin S. Carbajal;Benjamin M. Segal;Roman J. Giger

  • Anatomical distribution of the chemorepellent semaphorin III/collapsin‐1 in the adult rat and human brain: Predominant expression in structures of the olfactory‐hippocampal pathway and the motor system

    Roman J. Giger;R. Jeroen Pasterkamp;Stefan Heijnen;Anthony J.G.D. Holtmaat

  • Oligodendrocyte-Myelin Glycoprotein and Nogo Negatively Regulate Activity-Dependent Synaptic Plasticity

    Stephen J. Raiker;Hakjoo Lee;Katherine T. Baldwin;Yuntao Duan

  • Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons

    Jean François Cloutier;Roman J. Giger;Georgy Koentges;Catherine Dulac

  • Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.

    Ashley L Kalinski;Choya Yoon;Lucas D Huffman;Patrick C Duncker

  • The Nogo-66 Receptor NgR1 Is Required Only for the Acute Growth Cone-Collapsing But Not the Chronic Growth-Inhibitory Actions of Myelin Inhibitors

    Onanong Chivatakarn;Shinjiro Kaneko;Zhigang He;Marc Tessier-Lavigne

Frequent Co-Authors

Alex L. Kolodkin
Alex L. Kolodkin Johns Hopkins University School of Medicine
Benjamin M. Segal
Benjamin M. Segal The Ohio State University
Joost Verhaagen
Joost Verhaagen Netherlands Institute for Neuroscience
Peter Shrager
Peter Shrager University of Rochester Medical Center
David D. Ginty
David D. Ginty Howard Hughes Medical Institute
Miriam H. Meisler
Miriam H. Meisler University of Michigan–Ann Arbor
Christoph Rader
Christoph Rader Scripps Research Institute
Anthony Holtmaat
Anthony Holtmaat University of Geneva
Yutaka Yoshida
Yutaka Yoshida Cornell University
Alain Chédotal
Alain Chédotal Institut de la Vision

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