World's Best Scientists 2026 revealed!

Overview

Dennis O. Mook-Kanamori is affiliated with the Leiden University Medical Center in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Genetics, Epidemiology, Molecular Biology, Physiology, and Cardiology and Cardiovascular Medicine.

The scientist's work addresses various scientific topics, including Genetic Associations and Epidemiology, Liver Disease Diagnosis and Treatment, Birth, Development, and Health, Obesity, Physical Activity, and Diet, Lipid metabolism and disorders, Diet and metabolism studies, and Sleep and related disorders.

Recent publications by Dennis O. Mook-Kanamori include:

  • Genome-wide characterization of circulating metabolic biomarkers, 2024, Nature
  • Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts, 2022, Diabetes Care
  • Indoxyl sulfate, a gut microbiome-derived uremic toxin, is associated with psychic anxiety and its functional magnetic resonance imaging-based neurologic signature, 2021, Scientific Reports
  • Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals, 2020, Nature Genetics
  • Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus, 2023, Nature Human Behaviour

Frequent co-authors in their work include:

  • Raymond Noordam (21 publications)
  • Ruifang Li-Gao (17 publications)
  • Stella Trompet (16 publications)
  • M. Arfan Ikram (15 publications)
  • J. Wouter Jukema (14 publications)

The scientist commonly publishes in venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Nature Genetics, Scientific Reports, and Nature Human Behaviour.

Best Publications

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Aysu Okbay;Bart M L Baselmans;Jan-Emmanuel De Neve;Patrick Turley

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Connecting genetic risk to disease end points through the human blood plasma proteome.

    Karsten Suhre;Matthias Arnold;Aditya Mukund Bhagwat;Richard J. Cotton

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Genome-wide associations for birth weight and correlations with adult disease

    Momoko Horikoshi;Robin N. Beaumont;Felix R. Day;Nicole M. Warrington;Nicole M. Warrington

  • A genome-wide association meta-analysis identifies new childhood obesity loci

    JP Bradfield;HR Taal;NJ Timpson;A Scherag

  • Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

    A Giri;J N Hellwege;J M Keaton;J M Keaton;J Park

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

    Anubha Mahajan;Jennifer Wessel;Sara M. Willems;Wei Zhao

  • PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

    Amand F Schmidt;Daniel I Swerdlow;Daniel I Swerdlow;Michael V Holmes;Michael V Holmes;Riyaz S Patel;Riyaz S Patel

  • Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

    Caroline E. Dale;Ghazaleh Fatemifar;Tom M. Palmer;Jon White

  • New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

    Momoko Horikoshi;Hanieh Yaghootkar;Dennis O. Mook-Kanamori;Dennis O. Mook-Kanamori;Ulla Sovio;Ulla Sovio

  • Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

    Adrienne Tin;Jonathan Marten;Victoria L. Halperin Kuhns;Yong Li

  • Risk Factors and Outcomes Associated With First-Trimester Fetal Growth Restriction

    Dennis O. Mook-Kanamori;Eric A. P. Steegers;Paul H. Eilers;Hein Raat

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

  • New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

    Momoko Horikoshi;Hanieh Yaghootkar;Dennis O. Mook-Kanamori;Ulla Sovio

  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Aysu Okbay;Bart M. L. Baselmans;Jan-Emmanuel De Neve;Patrick Turley

Frequent Co-Authors

André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Albert V. Smith
Albert V. Smith University of Michigan–Ann Arbor
Daniel I. Chasman
Daniel I. Chasman Brigham and Women's Hospital
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Andrew P. Morris
Andrew P. Morris University of Liverpool
Vilmundur Gudnason
Vilmundur Gudnason University of Iceland
Kent D. Taylor
Kent D. Taylor David Geffen School of Medicine at UCLA
Zoltán Kutalik
Zoltán Kutalik University of Lausanne
Xiuqing Guo
Xiuqing Guo Lundquist Institute

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