World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
34294
World Ranking
10507
National Ranking
4558

Overview

Donna Rennick is affiliated with MSD (United States) and conducts research primarily within the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their scholarly work addresses several subfields, including Epidemiology, Infectious Diseases, and Molecular Biology.

The scientist's research topics focus on areas such as Microscopic Colitis, Clostridium difficile and Clostridium perfringens research, and Gut microbiota and health. This thematic concentration reflects an interest in gastrointestinal diseases and the role of microbial flora in health and disease progression.

Donna Rennick has contributed to the academic community with publications including:

  • Resident Enteric Bacteria Are Necessary for Development of Spontaneous Colitis and Immune System Activation in Interleukin-10-Deficient Mice, 2020, UNC Libraries

Collaborations have been central to their research output, frequently coauthoring with the following researchers:

  • Rance K. Sellon
  • Susan L. Tonkonogy
  • Michael Schultz
  • Levinus A. Dieleman
  • Wetonia B. Grenther

Their publication venues include:

  • UNC Libraries

Best Publications

  • Interleukin-10-deficient mice develop chronic enterocolitis

    Ralf Kühn;Jürgen Löhler;Donna Rennick;Klaus Rajewsky

  • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

    Birgit Oppmann;Robin Lesley;Bianca Blom;Jackie C. Timans

  • IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

    David Yen;Jeanne Cheung;Heleen Scheerens;Frédérique Poulet

  • IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

    Stefan Pflanz;Jackie C Timans;Jeanne Cheung;Rency Rosales

  • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice.

    Rance K. Sellon;Susan Tonkonogy;Michael Schultz;Levinus A. Dieleman

  • A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

    Christi Parham;Madaline Chirica;Jacqueline Timans;Elena Vaisberg

  • IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo.

    Madeline M. Fort;Jeanne Cheung;David Yen;Joana Li

  • Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice.

    Robert L. Coffman;Brian W. P. Seymour;Susan Hudak;John Jackson

  • Interleukin 10: a novel stimulatory factor for mast cells and their progenitors.

    L Thompson-Snipes;V Dhar;M W Bond;T R Mosmann

  • Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

    F Lee;T Yokota;T Otsuka;P Meyerson

  • Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

    C. Hannum;J. Culpepper;D. Campbell;T. McClanahan

  • Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells

    Takashi Yokota;Frank Lee;Donna Rennick;Carol Hall

  • IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi.

    C A Hunter;L A Ellis-Neyes;T Slifer;S Kanaly

  • Studies with IL-10-/- mice: an overview.

    Donna M. Rennick;Madeline M. Fort;Natalie J. Davidson

  • IL-12, but not IFN-gamma, plays a major role in sustaining the chronic phase of colitis in IL-10-deficient mice.

    Natalie J. Davidson;Susan A. Hudak;Robin E. Lesley;Satish Menon

  • Isolation of cDNA for a human granulocyte-macrophage colony-stimulating factor by functional expression in mammalian cells.

    Frank Lee;Takashi Yokota;Takeshi Otsuka;Lorraine Gemmell

  • Control of Hemopoiesis by a Bone Marrow Stromal Cell Clone: Lipopolysaccharide- and Interleukin-1--Inducible Production of Colony-Stimulating Factors

    D Rennick;G Yang;L Gemmell;F Lee

  • Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-) mice and intestinal inflammation.

    Donna M. Rennick;Madeline M. Fort

  • Requirements for Allergen-Induced Airway Hyperreactivity in T and B Cell-Deficient Mice

    David B. Corry;Gabriele Grünig;Husein Hadeiba;Viswanath P. Kurup

  • Interleukin 4 (B-cell stimulatory factor 1) can enhance or antagonize the factor-dependent growth of hemopoietic progenitor cells.

    Donna Rennick;Gloria Yang;Christa Muller-Sieburg;Craig Smith

Frequent Co-Authors

Takashi Yokota
Takashi Yokota Kanazawa University
Tim R. Mosmann
Tim R. Mosmann University of Rochester Medical Center
Frank S. Lee
Frank S. Lee University of Pennsylvania
Robert A. Kastelein
Robert A. Kastelein MSD (United States)
Robert L. Coffman
Robert L. Coffman University of California, Santa Cruz
Naoko Arai
Naoko Arai University of Tokyo
Ken-ichi Arai
Ken-ichi Arai University of Tokyo
Werner Müller
Werner Müller University of Manchester
Ralf Kühn
Ralf Kühn Max Delbrück Center for Molecular Medicine
Albert Zlotnik
Albert Zlotnik University of California, Irvine

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