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Takayuki Yoshimoto

Takayuki Yoshimoto

D-Index & Metrics

Immunology

D-Index
48
Citations
8300
World Ranking
4438
National Ranking
170

Overview

Takayuki Yoshimoto is a researcher affiliated with Tokyo Medical University in Japan, specializing primarily in the fields of Medicine and Immunology and Microbiology. Their work extensively covers topics related to mesenchymal stem cell research and immune system function.

Yoshimoto's main research areas include:

  • Mesenchymal stem cell research
  • Immune cell function and interaction
  • Immunotherapy and immune responses
  • Contact dermatitis and allergies
  • Hemostasis and retained surgical items
  • Wound healing and treatments
  • Breast cancer treatment studies

Their publications reflect a focus on these topics, appearing frequently in journals such as the International Journal of Molecular Sciences and Scientific Reports, as well as Frontiers in Immunology, Gels, and the Journal of Medical Case Reports. Yoshimoto has published notably in:

  • International Journal of Molecular Sciences (4 publications)
  • Scientific Reports (4 publications)
  • Frontiers in Immunology (2 publications)
  • Gels (2 publications)
  • Journal of Medical Case Reports (2 publications)

Recent research papers authored or co-authored by Yoshimoto include:

  • "Immortalization of Mesenchymal Stem Cells for Application in Regenerative Medicine and Their Potential Risks of Tumorigenesis" (2024, International Journal of Molecular Sciences)
  • "Rap1 prevents colitogenic Th17 cell expansion and facilitates Treg cell differentiation and distal TCR signaling" (2022, Communications Biology)
  • "Interleukin-1β in peripheral monocytes is associated with seizure frequency in pediatric drug-resistant epilepsy" (2021, Journal of Neuroimmunology)
  • "Chemical- and Drug-Induced Allergic, Inflammatory, and Autoimmune Diseases Via Haptenation" (2023, Biology)
  • "Water-Absorbing Bioadhesive Poly(Acrylic Acid)/Polyvinylpyrrolidone Complex Sponge for Hemostatic Agents" (2022, Bioengineering)

Yoshimoto has collaborated frequently with several co-authors, indicating active research partnerships. Key collaborators include:

  • Yasuhiro Katahira
  • Izuru Mizoguchi
  • Hideaki Hasegawa
  • Satomi Miyakawa
  • Shinya Inoué

Their publication record spans multiple subfields such as Immunology, Genetics, Oncology, Surgery, and Physiology. This interdisciplinary approach supports a range of investigations primarily focused on immune-related diseases, cancer treatments, and regenerative therapies.

Best Publications

  • The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis

    Christoph Hölscher;Alexandra Hölscher;Dominik Rückerl;Takayuki Yoshimoto

  • Potent Antitumor Activity of Interleukin-27

    Masayuki Hisada;Sadahiro Kamiya;Koji Fujita;Maria Laura Belladonna

  • An Indispensable Role for STAT1 in IL-27-Induced T-bet Expression but Not Proliferation of Naive CD4 + T Cells

    Sadahiro Kamiya;Toshiyuki Owaki;Noriko Morishima;Fumio Fukai

  • IL-27 Suppresses Th2 Cell Development and Th2 Cytokines Production from Polarized Th2 Cells: A Novel Therapeutic Way for Th2-Mediated Allergic Inflammation

    Tomohiro Yoshimoto;Takayuki Yoshimoto;Koubun Yasuda;Junichiro Mizuguchi

  • A Role for IL-27 in Early Regulation of Th1 Differentiation

    Toshiyuki Owaki;Masayuki Asakawa;Noriko Morishima;Kikumi Hata

  • Augmentation of Effector CD8 + T Cell Generation with Enhanced Granzyme B Expression by IL-27

    Noriko Morishima;Toshiyuki Owaki;Masayuki Asakawa;Sadahiro Kamiya

  • Regulation of Antitumor Immune Responses by the IL-12 Family Cytokines, IL-12, IL-23, and IL-27

    Mingli Xu;Izuru Mizoguchi;Noriko Morishima;Yukino Chiba

  • Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases

    Ning Qu;Mingli Xu;Izuru Mizoguchi;Jun Ichi Furusawa

  • Antiangiogenic and Antitumor Activities of IL-27

    Motomu Shimizu;Mariko Shimamura;Toshiyuki Owaki;Masayuki Asakawa

  • Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor

    Muhammad Shamsul Alam;Yoichi Maekawa;Akiko Kitamura;Kenji Tanigaki

  • Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes

    Hideki Nakano;Toshiki Tamura;Takayuki Yoshimoto;Hideo Yagita

  • Induction of IgG2a Class Switching in B Cells by IL-27

    Takayuki Yoshimoto;Keiko Okada;Keiko Okada;Noriko Morishima;Sadahiro Kamiya

  • IL-27 Suppresses CD28-Medicated IL-2 Production through Suppressor of Cytokine Signaling 3

    Toshiyuki Owaki;Masayuki Asakawa;Sadahiro Kamiya;Kiyoshi Takeda

  • Calpain-induced Bax-cleavage product is a more potent inducer of apoptotic cell death than wild-type Bax.

    Hiroko Toyota;Noriko Yanase;Takayuki Yoshimoto;Masami Moriyama

  • Interleukin-23 and interleukin-27 exert quite different antitumor and vaccine effects on poorly immunogenic melanoma.

    Shuntaro Oniki;Hiroshi Nagai;Tatsuya Horikawa;Junya Furukawa

  • Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family

    Hideaki Hasegawa;Izuru Mizoguchi;Yukino Chiba;Mio Ohashi

  • Antiproliferative Activity of IL-27 on Melanoma

    Takayuki Yoshimoto;Noriko Morishima;Izuru Mizoguchi;Motomu Shimizu

  • IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways.

    Toshiyuki Owaki;Masayuki Asakawa;Fumio Fukai;Junichiro Mizuguchi

  • Interferon-gamma is a therapeutic target molecule for prevention of postoperative adhesion formation.

    Hisashi Kosaka;Tomohiro Yoshimoto;Takayuki Yoshimoto;Jiro Fujimoto

  • Interleukin-27 Activates Natural Killer Cells and Suppresses NK-Resistant Head and Neck Squamous Cell Carcinoma through Inducing Antibody-Dependent Cellular Cytotoxicity

    Masahiro Matsui;Tsunao Kishida;Hiroshi Nakano;Koichiro Yoshimoto

Frequent Co-Authors

Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Daniel J. Cua
Daniel J. Cua Johnson & Johnson (United States)
Susumu Nakae
Susumu Nakae Hiroshima University
Tomohiro Yoshimoto
Tomohiro Yoshimoto Hyogo College of Medicine
Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Masahiko Kuroda
Masahiko Kuroda Tokyo Medical University
Hiroyasu Nakano
Hiroyasu Nakano Toho University
Kazuma Ohyashiki
Kazuma Ohyashiki Tokyo Medical University
Katsuko Sudo
Katsuko Sudo Tokyo Medical University
Stefan Ehlers
Stefan Ehlers Kiel University

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