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Robert A. Kastelein

Robert A. Kastelein

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 89 1092 990 586 522 188 70166

Robert A. Kastelein publications per year

The chart shows the history of publications by Robert A. Kastelein between 1978 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Robert A. Kastelein published across 48 years, from 1978 to 2025, averaging 4.5 papers a year. Output peaked at 17 publications in 2006. 1 of the 216 publications appeared in the last two years.

No. of publications
5 10 15
Bar chart. Horizontal axis: year, 1978 to 2025. Vertical axis: number of publications, 0 to 17. Peak 17 publications in 2006. 1978: 1 publication 1979: 0 publications 1980: 0 publications 1981: 0 publications 1982: 2 publications 1983: 3 publications 1984: 0 publications 1985: 1 publication 1986: 1 publication 1987: 2 publications 1988: 3 publications 1989: 2 publications 1990: 5 publications 1991: 5 publications 1992: 1 publication 1993: 1 publication 1994: 2 publications 1995: 4 publications 1996: 12 publications 1997: 8 publications 1998: 7 publications 1999: 4 publications 2000: 13 publications 2001: 15 publications 2002: 3 publications 2003: 7 publications 2004: 9 publications 2005: 7 publications 2006: 17 publications 2007: 15 publications 2008: 16 publications 2009: 9 publications 2010: 7 publications 2011: 4 publications 2012: 4 publications 2013: 6 publications 2014: 7 publications 2015: 2 publications 2016: 3 publications 2017: 0 publications 2018: 0 publications 2019: 1 publication 2020: 2 publications 2021: 3 publications 2022: 0 publications 2023: 1 publication 2024: 0 publications 2025: 1 publication
1978 2025

216 publications in total across all disciplines

View publications per year as a table
Robert A. Kastelein: publications per year, 1978 to 2025
Year Publications
1978 1
1979 0
1980 0
1981 0
1982 2
1983 3
1984 0
1985 1
1986 1
1987 2
1988 3
1989 2
1990 5
1991 5
1992 1
1993 1
1994 2
1995 4
1996 12
1997 8
1998 7
1999 4
2000 13
2001 15
2002 3
2003 7
2004 9
2005 7
2006 17
2007 15
2008 16
2009 9
2010 7
2011 4
2012 4
2013 6
2014 7
2015 2
2016 3
2017 0
2018 0
2019 1
2020 2
2021 3
2022 0
2023 1
2024 0
2025 1
Total 216
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Robert A. Kastelein publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Robert A. Kastelein sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 182–191 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 188 publications — 30th percentile

30% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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Robert A. Kastelein D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Robert A. Kastelein sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 88–89 D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 89 D-Index — 78th percentile

78% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96 89
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96
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Overview

Robert A. Kastelein is affiliated with MSD in the United States and has contributed to research primarily within the fields of medicine and immunology and microbiology. Their work emphasizes oncology, immunology, radiology, nuclear medicine and imaging, and biotechnology.

The main research topics covered by Robert A. Kastelein include:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • Immune Cell Function and Interaction
  • Cancer Research and Treatments

Recent publications by Robert A. Kastelein demonstrate involvement in cancer immunotherapy and pharmacokinetic studies. Notable papers include:

  • Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab, 2020, Molecular Cancer Therapeutics
  • Abstract 1833: Novel IL-12 Partial Agonist For Cancer Immunotherapy Avoids NK-cell Mediated Toxicity, 2023, Cancer Research

The researcher has collaborated frequently with several co-authors, reflecting interdisciplinary teamwork. Frequent co-authors include:

  • René de Waal Malefyt
  • Beth Hutchins
  • Gary C. Starling
  • Mark A. McCoy
  • Danuta J. Herzyk

Robert A. Kastelein has published in venues such as Molecular Cancer Therapeutics and Cancer Research, indicating a focus on oncology and immunology journals.

Best Publications

  • IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

    Claire L. Langrish;Yi Yi Chen;Wendy M Blumenschein;Jeanine D. Mattson

  • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

    Jochen Schmitz;Alexander Owyang;Elizabeth Oldham;Yaoli Song

  • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

    Daniel J. Cua;Jonathan Sherlock;Yi Chen;Craig A. Murphy

  • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

    Birgit Oppmann;Robin Lesley;Bianca Blom;Jackie C. Timans

  • Development, cytokine profile and function of human interleukin 17-producing helper T cells

    Nicholas J Wilson;Katia Boniface;Jason R Chan;Brent S McKenzie

  • Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP

    Vassili Soumelis;Pedro A Reche;Holger Kanzler;Wei Yuan

  • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens.

    Norimitsu Kadowaki;Stephen Ho;Svetlana Antonenko;Rene de Waal Malefyt

  • A family of human receptors structurally related to Drosophila Toll

    F L Rock;G Hardiman;J C Timans;R A Kastelein

  • Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

    Craig A. Murphy;Claire L. Langrish;Yi Yi Chen;Wendy M Blumenschein

  • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

    R de Waal Malefyt;J Haanen;H Spits;M G Roncarolo

  • IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

    David Yen;Jeanne Cheung;Heleen Scheerens;Frédérique Poulet

  • IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

    Stefan Pflanz;Jackie C Timans;Jeanne Cheung;Rency Rosales

  • A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

    Christi Parham;Madaline Chirica;Jacqueline Timans;Elena Vaisberg

  • IL-23 promotes tumour incidence and growth

    John L. Langowski;Xueqing Zhang;Lingling Wu;Jeanine D. Mattson

  • The IL-12 Family of Heterodimeric Cytokines: New Players in the Regulation of T Cell Responses

    Giorgio Trinchieri;Stefan Pflanz;Robert A Kastelein

  • Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

    Frank A. W. Verreck;Tjitske de Boer;Dennis M. L. Langenberg;Marieke A. Hoeve

  • IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells

    Jonathan P Sherlock;Barbara Joyce-Shaikh;Scott P Turner;Cheng-Chi Chao

  • Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

    P Vieira;R de Waal-Malefyt;M N Dang;K E Johnson

  • Understanding the IL-23–IL-17 immune pathway

    Brent S. McKenzie;Robert A. Kastelein;Daniel J. Cua

  • Discovery and Biology of IL-23 and IL-27: Related but Functionally Distinct Regulators of Inflammation

    Robert A. Kastelein;Christopher A. Hunter;Daniel J. Cua

Frequent Co-Authors

J. Fernando Bazan
J. Fernando Bazan Stanford University
Terrill K. McClanahan
Terrill K. McClanahan MSD (United States)
Daniel J. Cua
Daniel J. Cua Johnson & Johnson (United States)
Christopher A. Hunter
Christopher A. Hunter University of Pennsylvania
Sandra Zurawski
Sandra Zurawski Baylor University
Donna Rennick
Donna Rennick MSD (United States)
Yong-Jun Liu
Yong-Jun Liu University of Washington
Robert L. Coffman
Robert L. Coffman University of California, Santa Cruz
Gottfried Alber
Gottfried Alber Leipzig University
David Artis
David Artis Cornell University

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