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D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
39216
World Ranking
6839
National Ranking
3155

Overview

J. Fernando Bazan is affiliated with Stanford University in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses subfields such as molecular biology, immunology, oncology, endocrine and autonomic systems, and epidemiology.

Their work focuses on several key topics including regulation of appetite and obesity, Hedgehog signaling pathway studies, RNA modifications and cancer, cytokine signaling pathways and interactions, adipokines, inflammation, and metabolic diseases, adipose tissue and metabolism, as well as epigenetics and DNA methylation.

J. Fernando Bazan has published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), PLoS Biology, Nature Chemical Biology, Nature, and Nature Structural & Molecular Biology.

Recent papers include:

  • TMEM164 is an acyltransferase that forms ferroptotic C20:4 ether phospholipids, 2023, Nature Chemical Biology
  • Structural basis of cytokine-mediated activation of ALK family receptors, 2021, Nature
  • Mechanism of receptor assembly via the pleiotropic adipokine Leptin, 2023, Nature Structural & Molecular Biology
  • TMEM161B regulates cerebral cortical gyration, Sonic Hedgehog signaling, and ciliary structure in the developing central nervous system, 2023, Proceedings of the National Academy of Sciences
  • Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis, 2022, Developmental Cell

Frequent collaborators in their research include Savvas N. Savvides, Jan Félix, Alex Reed, Timothy B. Ware, and Benjamin F. Cravatt.

Best Publications

  • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

    Jochen Schmitz;Alexander Owyang;Elizabeth Oldham;Yaoli Song

  • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12.

    Birgit Oppmann;Robin Lesley;Bianca Blom;Jackie C. Timans

  • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens.

    Norimitsu Kadowaki;Stephen Ho;Svetlana Antonenko;Rene de Waal Malefyt

  • IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

    Stefan Pflanz;Jackie C Timans;Jeanne Cheung;Rency Rosales

  • A Core Complex of BBS Proteins Cooperates with the GTPase Rab8 to Promote Ciliary Membrane Biogenesis

    Maxence V. Nachury;Alexander V. Loktev;Qihong Zhang;Christopher J. Westlake

  • cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2

    Jean Gautier;Mark J. Solomon;Robert N. Booher;J.Fernando Bazan

  • Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

    David J. Rawlings;Douglas C. Saffran;Satoshi Tsukada;David A. Largaespada

  • Haemopoietic receptors and helical cytokines

    J.Fernando Bazan

  • Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma

    Robert L. Yauch;Gerrit J. P. Dijkgraaf;Bruno Alicke;Thomas Januario

  • Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38

    M. Howard;J. C. Grimaldi;J. F. Bazan;F. E. Lund

  • Lymphotactin: a cytokine that represents a new class of chemokine

    Gregory S. Kelner;Jacqueline Kennedy;Kevin B. Bacon;Sarah Kleyensteuber

  • WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27

    Stefan Pflanz;Linda Hibbert;Jeanine Mattson;Rency Rosales

  • The Conserved Bardet-Biedl Syndrome Proteins Assemble a Coat that Traffics Membrane Proteins to Cilia

    Hua Jin;Susan Roehl White;Toshinobu Shida;Stefan Schulz

  • Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

    Liyun Sang;Julie J. Miller;Kevin C. Corbit;Rachel H. Giles

  • Neuropoietic cytokines in the hematopoietic fold

    J.Fernando Bazan

  • Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs

    C. Hannum;J. Culpepper;D. Campbell;T. McClanahan

  • Human Thymic Stromal Lymphopoietin Preferentially Stimulates Myeloid Cells

    Pedro A. Reche;Vassili Soumelis;Daniel M. Gorman;Teresa Clifford

  • Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications.

    J F Bazan;R J Fletterick

  • DUBA: a deubiquitinase that regulates type I interferon production.

    Nobuhiko Kayagaki;Qui Phung;Salina Chan;Ruchir Chaudhari

  • Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.

    T J Chambers;R C Weir;A Grakoui;D W McCourt

Frequent Co-Authors

Robert A. Kastelein
Robert A. Kastelein MSD (United States)
Yong-Jun Liu
Yong-Jun Liu University of Washington
Albert Zlotnik
Albert Zlotnik University of California, Irvine
Gerard Zurawski
Gerard Zurawski Baylor University
Sandra Zurawski
Sandra Zurawski Baylor University
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center
Debra J. Gilbert
Debra J. Gilbert National Institutes of Health
Val C. Sheffield
Val C. Sheffield University of Iowa

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