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Immunology

D-Index
99
Citations
41711
World Ranking
742
National Ranking
423

Medicine

D-Index
99
Citations
41859
World Ranking
8507
National Ranking
4389

Overview

Charles O. Elson is affiliated with the University of Alabama at Birmingham in the United States. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics, and Molecular Biology. Within these domains, their work focuses heavily on Immunology, Genetics, Hematology, Oncology, and Epidemiology as subfields.

The scientist's research topics include:

  • T-cell and B-cell Immunology
  • Hematopoietic Stem Cell Transplantation
  • Immune Cell Function and Interaction
  • Inflammatory Bowel Disease
  • CAR-T cell therapy research
  • Microscopic Colitis
  • Immunotherapy and Immune Responses

They have published extensively in several journals and venues. Frequent publication venues include:

  • Zenodo (CERN European Organization for Nuclear Research)
  • Gastroenterology
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Crohn's and Colitis

Among their recent papers are:

  • "Ulcerative colitis is characterized by a plasmablast-skewed humoral response associated with disease activity," 2022, Nature Medicine
  • "Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn's Disease," 2021, Gastroenterology
  • "CD4 + T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitis," 2020, Science Immunology
  • "Synchronization of mothers and offspring promotes tolerance and limits allergy," 2020, JCI Insight
  • "Remodeling of colon plasma cell repertoire within ulcerative colitis patients," 2023, The Journal of Experimental Medicine

Frequent collaborators in their research include Lennard W. Duck, Albert C. Yeh, Motoko Koyama, Olivia G. Waltner, and Simone A. Minnie. These coauthors have each contributed extensively to joint research efforts.

Best Publications

  • Transforming growth factor-beta induces development of the T(H)17 lineage.

    Paul R. Mangan;Laurie E. Harrington;Darrell B. O'Quinn;Whitney S. Helms

  • The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

    Sophie Viaud;Sophie Viaud;Fabiana Saccheri;Grégoire Mignot;Takahiro Yamazaki

  • Reciprocal Interactions of the Intestinal Microbiota and Immune System

    Craig L. Maynard;Charles O. Elson;Robin D. Hatton;Casey T. Weaver

  • Experimental models of inflammatory bowel disease

    Charles O. Elson;Ryan Balfour Sartor;Gary S. Tennyson;Robert H. Riddell

  • Late Developmental Plasticity in the T Helper 17 Lineage

    Yun Kyung Lee;Henrietta Turner;Craig L. Maynard;James R. Oliver

  • Anti-interleukin-12 antibody for active Crohn's disease

    Peter J. Mannon;Ivan J. Fuss;Lloyd Mayer;Charles O. Elson

  • Bacterial flagellin is a dominant antigen in Crohn disease

    Michael J. Lodes;Yingzi Cong;Charles O. Elson;Raodoh Mohamath

  • Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice

    L A Dieleman;B U Ridwan;G S Tennyson;K W Beagley

  • Innate lymphoid cells regulate CD4 + T-cell responses to intestinal commensal bacteria

    Matthew R. Hepworth;Laurel A. Monticelli;Thomas C. Fung;Carly G.K. Ziegler

  • Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease

    Richard N. Fedorak;Alfred Gangl;Charles O. Elson;Paul Rutgeerts

  • Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues.

    J Xu-Amano;H Kiyono;R J Jackson;H F Staats

  • Experimental Models of Inflammatory Bowel Disease Reveal Innate, Adaptive, and Regulatory Mechanisms of Host Dialogue With the Microbiota

    Charles O. Elson;Yingzi Cong;Vance J. McCracken;Reed A. Dimmitt

  • Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin.

    C O Elson;W Ealding

  • Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice.

    Charles O. Elson;Yingzi Cong;Casey T. Weaver;Trenton R. Schoeb

  • Antibodies to CBir1 flagellin define a unique response that is associated independently with complicated Crohn's disease.

    Stephan R. Targan;Carol J. Landers;Huiying Yang;Michael J. Lodes;Michael J. Lodes

  • Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4+ T cells

    Matthew R. Hepworth;Thomas C. Fung;Thomas C. Fung;Samuel H. Masur;Judith R. Kelsen

  • CD4+ T Cells Reactive to Enteric Bacterial Antigens in Spontaneously Colitic C3H/HeJBir Mice: Increased T Helper Cell Type 1 Response and Ability to Transfer Disease

    Yingzi Cong;Steven L. Brandwein;Robert P. McCabe;A. Lazenby

  • The Th17 Pathway and Inflammatory Diseases of the Intestines, Lungs, and Skin

    Casey T. Weaver;Charles O. Elson;Lynette A. Fouser;Jay K. Kolls

  • Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis

    Michael Mähler;Ian J. Bristol;Edward H. Leiter;Aletha E. Workman

  • Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group.

    S.J.H. van Deventer;C.O. Elson;R.N. Fedorak

Frequent Co-Authors

Yingzi Cong
Yingzi Cong The University of Texas Medical Branch at Galveston
Casey T. Weaver
Casey T. Weaver University of Alabama at Birmingham
Jiri Mestecky
Jiri Mestecky University of Alabama at Birmingham
John P. Sundberg
John P. Sundberg Vanderbilt University
Stephan R. Targan
Stephan R. Targan Cedars-Sinai Medical Center
Warren Strober
Warren Strober National Institute of Allergy and Infectious Diseases
Kenneth W. Beagley
Kenneth W. Beagley Queensland University of Technology
Etty N. Benveniste
Etty N. Benveniste University of Alabama at Birmingham
Jerry R. McGhee
Jerry R. McGhee University of Alabama at Birmingham
Hiroshi Kiyono
Hiroshi Kiyono University of Tokyo

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Related Online Degrees & Career Pathways

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