World's Best Scientists 2026 revealed!
Kazuhiko Yanai

Kazuhiko Yanai

D-Index & Metrics

Neuroscience

D-Index
80
Citations
19558
World Ranking
1638
National Ranking
35

Medicine

D-Index
80
Citations
19612
World Ranking
17278
National Ranking
554

Overview

Kazuhiko Yanai is affiliated with Tohoku University in Japan and has contributed extensively to the fields of medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their research spans several subfields including molecular biology, physiology, neurology, immunology, and radiology, nuclear medicine, and imaging.

The scientist's work addresses various main topics, such as:

  • Mast cells and histamine
  • Alzheimer's disease research and treatments
  • Sleep and wakefulness research
  • Neuroinflammation and neurodegeneration mechanisms
  • Circadian rhythm and melatonin
  • Olfactory and sensory function studies
  • Radiopharmaceutical chemistry and applications

Kazuhiko Yanai has published frequently in a range of scientific venues, notably including:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Journal of Nuclear Medicine
  • Current Topics in Behavioral Neurosciences
  • Neuropharmacology
  • Scientific Reports

Recent publications include:

  • 18F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging, 2020, Journal of Nuclear Medicine
  • Histaminergic neurons in the tuberomammillary nucleus as a control centre for wakefulness, 2020, British Journal of Pharmacology
  • First-in-Humans Evaluation of 18F-SMBT-1, a Novel 18F-Labeled Monoamine Oxidase-B PET Tracer for Imaging Reactive Astrogliosis, 2022, Journal of Nuclear Medicine
  • Assessing Reactive Astrogliosis with 18F-SMBT-1 Across the Alzheimer Disease Spectrum, 2022, Journal of Nuclear Medicine
  • Imaging of Reactive Astrogliosis by Positron Emission Tomography, 2022, Frontiers in Neuroscience

Frequent collaborators include:

  • Takeo Yoshikawa
  • Nobuyuki Okamura
  • Ryuichi Harada
  • Yukitsuka Kudo
  • Shozo Furumoto

Best Publications

  • 18F-THK523: a novel in vivo tau imaging ligand for Alzheimer’s disease

    Michelle T Fodero-Tavoletti;Nobuyuki Okamura;Shozo Furumoto;Rachel S Mulligan

  • Psychosis pathways converge via D2high dopamine receptors.

    Philip Seeman;Johannes Schwarz;Jiang Fan Chen;Henry Szechtman

  • 18F-THK5351: A Novel PET Radiotracer for Imaging Neurofibrillary Pathology in Alzheimer Disease.

    Ryuichi Harada;Nobuyuki Okamura;Shozo Furumoto;Katsutoshi Furukawa

  • Specific brain processing of facial expressions in people with alexithymia: an H215O‐PET study

    Michiko Kano;Shin Fukudo;Jiro Gyoba;Miyuki Kamachi

  • Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors

    Isao Inoue;Kazuhiko Yanai;Daisuke Kitamura;Ichiro Taniuchi

  • Novel 18F-labeled arylquinoline derivatives for noninvasive imaging of tau pathology in Alzheimer disease.

    Nobuyuki Okamura;Shozo Furumoto;Ryuichi Harada;Tetsuro Tago

  • 2-(2-[2-Dimethylaminothiazol-5-yl]Ethenyl)-6- (2-[Fluoro]Ethoxy)Benzoxazole: A Novel PET Agent for In Vivo Detection of Dense Amyloid Plaques in Alzheimer's Disease Patients

    Yukitsuka Kudo;Nobuyuki Okamura;Shozo Furumoto;Manabu Tashiro

  • Non-invasive assessment of Alzheimer's disease neurofibrillary pathology using 18F-THK5105 PET.

    Nobuyuki Okamura;Shozo Furumoto;Michelle T. Fodero-Tavoletti;Rachel S. Mulligan

  • Consensus group on new‐generation antihistamines (CONGA): present status and recommendations

    S. T. Holgate;G. W. Canonica;F. E. R. Simons;M. Taglialatela

  • Behavioral Characterization of Mice Lacking Histamine H3 Receptors

    Hiroshi Toyota;Christine Dugovic;Muriel Koehl;Aaron D. Laposky

  • Quinoline and Benzimidazole Derivatives: Candidate Probes for In Vivo Imaging of Tau Pathology in Alzheimer's Disease

    Nobuyuki Okamura;Takahiro Suemoto;Shozo Furumoto;Masako Suzuki

  • Imaging of central itch modulation in the human brain using positron emission tomography.

    Hideki Mochizuki;Manabu Tashiro;Michiko Kano;Yumiko Sakurada

  • The physiological and pathophysiological roles of neuronal histamine: an insight from human positron emission tomography studies.

    Kazuhiko Yanai;Manabu Tashiro

  • Propagation of pathological α-synuclein in marmoset brain.

    Aki Shimozawa;Aki Shimozawa;Maiko Ono;Maiko Ono;Daisuke Takahara;Airi Tarutani;Airi Tarutani

  • Roles of histamine in regulation of arousal and cognition : functional neuroimaging of histamine H1 receptors in human brain

    Manabu Tashiro;Hideki Mochizuki;Kentaro Iwabuchi;Yumiko Sakurada

  • In vivo evaluation of a novel tau imaging tracer for Alzheimer’s disease

    Victor L. Villemagne;Shozo Furumoto;Michelle T. Fodero-Tavoletti;Rachel S. Mulligan

  • Tau PET imaging in Alzheimer's disease.

    Nobuyuki Okamura;Ryuichi Harada;Shozo Furumoto;Hiroyuki Arai

  • Cerebral circulation and oxygen metabolism associated with subclinical periventricular hyperintensity as shown by magnetic resonance imaging

    Kenichi Meguro;Jun Hatazawa;Tatsuo Yamaguchi;Masatoshi Itoh

  • Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls

    Seiji Nishino;Eiko Sakurai;Sona Nevsimalova;Yasushi Yoshida

  • Role of histamine H1 receptor in pain perception: a study of the receptor gene knockout mice

    Jalal Izadi Mobarakeh;Shinobu Sakurada;Sou Katsuyama;Motoharu Kutsuwa

Frequent Co-Authors

Nobuyuki Okamura
Nobuyuki Okamura Tohoku Medical and Pharmaceutical University
Manabu Tashiro
Manabu Tashiro Tohoku University
Hiroyuki Arai
Hiroyuki Arai University of Tokyo
Masatoshi Itoh
Masatoshi Itoh Tohoku University
Victor L. Villemagne
Victor L. Villemagne University of Pittsburgh
Christopher C. Rowe
Christopher C. Rowe University of Melbourne
Hiroshi Fukuda
Hiroshi Fukuda Tohoku University
Shinobu Sakurada
Shinobu Sakurada Tohoku Medical and Pharmaceutical University
Hideki Mochizuki
Hideki Mochizuki Osaka University
Makoto Higuchi
Makoto Higuchi National Institutes for Quantum and Radiological Science and Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Kazuhiko Yanai

Trending Scientists

Recently Published Articles