World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
17057
World Ranking
11190
National Ranking
767

Overview

Ichiro Taniuchi is affiliated with the RIKEN Center for Integrative Medical Sciences in Japan, focusing primarily on immunology and microbiology, medicine, and biochemistry, genetics, and molecular biology. Their scholarly work explores several subfields, notably immunology, molecular biology, oncology, hematology, and cancer research.

The scientist's research frequently centers on topics such as immune cell function and interaction, T-cell and B-cell immunology, CAR-T cell therapy research, immunotherapy and immune responses, acute myeloid leukemia research, cancer-related gene regulation, and the role of immune cells in cancer.

Among their recent papers are:

  • TGF-β suppresses type 2 immunity to cancer (2020, Nature)
  • Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity (2020, Nature Communications)
  • Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding (2020, Science Immunology)
  • A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS (2021, Nature Immunology)
  • The Roles of RUNX Family Proteins in Development of Immune Cells (2020, PubMed)

These studies have been published predominantly in venues that include Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Nature Immunology, and Science Immunology.

Ichiro Taniuchi has collaborated frequently with several scientists, including Motoi Yamashita, Kazuki Okuyama, Aneela Nomura, Wooseok Seo, and Sawako Muroi.

Best Publications

  • Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

    Yong-Rui Zou;Andreas H. Kottmann;Masahiko Kuroda;Ichiro Taniuchi

  • Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

    Ichiro Taniuchi;Motomi Osato;Takeshi Egawa;Mary Jean Sunshine

  • Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

    Hirofumi Nishizumi;Ichiro Taniuchi;Yuji Yamanashi;Daisuke Kitamura

  • Flexible Use of Nuclear Import Pathways by HIV-1

    KyeongEun Lee;Zandrea Ambrose;Thomas D. Martin;Ilker Oztop

  • Transcriptional reprogramming of mature CD4+ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

    Daniel Mucida;Mohammad Mushtaq Husain;Sawako Muroi;Femke Van Wijk

  • Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors

    Isao Inoue;Kazuhiko Yanai;Daisuke Kitamura;Ichiro Taniuchi

  • Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment

    Yohko Kitagawa;Naganari Ohkura;Yujiro Kidani;Alexis Vandenbon

  • The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

    Takeshi Egawa;Robert E. Tillman;Yoshinori Naoe;Ichiro Taniuchi

  • A Role for Runx Transcription Factor Signaling in Dorsal Root Ganglion Sensory Neuron Diversification

    Ina Kramer;Markus Sigrist;Joriene C. de Nooij;Ichiro Taniuchi

  • Genetic evidence supporting selection of the Vα14i NKT cell lineage from double-positive thymocyte precursors

    Takeshi Egawa;Gerard Eberl;Ichiro Taniuchi;Kamel Benlagha

  • Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

    Tian H. Chi;Mimi Wan;Keji Zhao;Ichiro Taniuchi

  • Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

    Ruka Setoguchi;Masashi Tachibana;Yoshinori Naoe;Sawako Muroi

  • Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4 + T cell immunity

    Bernardo Sgarbi Reis;Aneta Rogoz;Frederico Azevedo Costa-Pinto;Frederico Azevedo Costa-Pinto;Ichiro Taniuchi

  • Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells

    Akihiko Kitoh;Masahiro Ono;Masahiro Ono;Yoshinori Naoe;Naganari Ohkura;Naganari Ohkura

  • RUNX proteins in transcription factor networks that regulate T-cell lineage choice.

    Amélie Collins;Dan R. Littman;Ichiro Taniuchi

  • Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity

    Yoichi Maekawa;Yoshiaki Minato;Chieko Ishifune;Takeshi Kurihara

  • Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer

    Yoshinori Naoe;Ruka Setoguchi;Kaori Akiyama;Sawako Muroi

  • Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.

    Kosuke Hashimoto;Tsukasa Kouno;Tomokatsu Ikawa;Norihito Hayatsu

  • Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

    Ming Yu;Tali Mazor;Hui Huang;Hsuan-Ting Huang

  • Glycosylphosphatidylinositol-anchor-deficient mice: implications for clonal dominance of mutant cells in paroxysmal nocturnal hemoglobinuria

    Kazuyoshi Kawagoe;Daisuke Kitamura;Masaru Okabe;Ichiro Taniuchi

Frequent Co-Authors

Dan R. Littman
Dan R. Littman New York University
Wilfried Ellmeier
Wilfried Ellmeier Medical University of Vienna
Motomi Osato
Motomi Osato National University of Singapore
Shimon Sakaguchi
Shimon Sakaguchi Osaka University
Daisuke Kitamura
Daisuke Kitamura Tokyo University of Science
Yoshiaki Ito
Yoshiaki Ito National University of Singapore
Hiroshi Kawamoto
Hiroshi Kawamoto Kyoto University
Mitchell Kronenberg
Mitchell Kronenberg University of California, San Diego
Terumi Kohwi-Shigematsu
Terumi Kohwi-Shigematsu Lawrence Berkeley National Laboratory
Leonard I. Zon
Leonard I. Zon Harvard University

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