World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
80
Citations
22564
World Ranking
17150
National Ranking
8594

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Cancer
  • Gene

Jack W. Singer spends much of his time researching Internal medicine, Surgery, Immunology, Bone marrow and Gastroenterology. His Internal medicine research incorporates themes from Endocrinology and Oncology. His work in Immunology covers topics such as Stem cell which are related to areas like Molecular biology and Clone.

His Bone marrow study integrates concerns from other disciplines, such as Recombinant DNA, Microgram, Complication, Granulocyte macrophage colony-stimulating factor and Acute lymphocytic leukemia. His research in Gastroenterology intersects with topics in Methotrexate, Cyclophosphamide, Chemotherapy, Transplantation and Immunotherapy. His biological study spans a wide range of topics, including Clinical trial and Absolute neutrophil count.

His most cited work include:

  • Cisplatin-based adjuvant chemotherapy in patients with completely resected non-small-cell lung cancer. (1755 citations)
  • One hundred patients with acute leukemia treated by chemotherapy, total body irradiation, and allogeneic marrow transplantation. (789 citations)
  • Mechanisms of action of arsenic trioxide. (778 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Internal medicine, Immunology, Surgery, Bone marrow and Haematopoiesis. The Internal medicine study combines topics in areas such as Gastroenterology and Oncology. The concepts of his Immunology study are interwoven with issues in Progenitor cell, Stem cell and Molecular biology.

His work on Transplantation, Chemotherapy and Regimen as part of general Surgery study is frequently linked to Placebo, bridging the gap between disciplines. His Bone marrow research includes elements of Acute lymphocytic leukemia and Granulocyte macrophage colony-stimulating factor. His work carried out in the field of Haematopoiesis brings together such families of science as Cell, Peripheral blood mononuclear cell, Philadelphia chromosome and Pathology.

He most often published in these fields:

  • Internal medicine (34.16%)
  • Immunology (38.27%)
  • Surgery (23.46%)

What were the highlights of his more recent work (between 2009-2020)?

  • Internal medicine (34.16%)
  • Pacritinib (7.00%)
  • Pharmacology (11.52%)

In recent papers he was focusing on the following fields of study:

His main research concerns Internal medicine, Pacritinib, Pharmacology, Surgery and Pixantrone. His work deals with themes such as Gastroenterology and Oncology, which intersect with Internal medicine. In his study, CHOP, Ejection fraction, Vincristine, Mantle cell lymphoma and Cyclophosphamide is strongly linked to Diffuse large B-cell lymphoma, which falls under the umbrella field of Gastroenterology.

His study in Pacritinib is interdisciplinary in nature, drawing from both Cancer research, Janus kinase 2 and Immune system. His Pharmacology research is multidisciplinary, incorporating perspectives in Cancer cell, Paclitaxel, Paclitaxel Poliglumex and Erlotinib. In his study, which falls under the umbrella issue of Pixantrone, International Prognostic Index, Ifosfamide and Progressive disease is strongly linked to Aggressive Non-Hodgkin Lymphoma.

Between 2009 and 2020, his most popular works were:

  • Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial (91 citations)
  • Pixantrone dimaleate versus other chemotherapeutic agents as a single-agent salvage treatment in patients with relapsed or refractory aggressive non-Hodgkin lymphoma: a phase 3, multicentre, open-label, randomised trial. (81 citations)
  • Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial (78 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Cancer
  • Gene

His primary areas of study are Internal medicine, Pacritinib, Surgery, Pixantrone and Myelofibrosis. His work in Internal medicine is not limited to one particular discipline; it also encompasses Gastroenterology. His studies examine the connections between Gastroenterology and genetics, as well as such issues in Diffuse large B-cell lymphoma, with regards to Pharmacology.

His Pacritinib study incorporates themes from Cancer research and Janus kinase 2. Jack W. Singer has researched Surgery in several fields, including Rituximab, Lymphoma and Oncology. His research on Myelofibrosis also deals with topics like

  • Randomized controlled trial together with Ruxolitinib,
  • Clinical endpoint together with Nausea and Cytopenia,
  • Adverse effect, which have a strong connection to Neutropenia.

Best Publications

  • Mechanisms of action of arsenic trioxide.

    Wilson H. Miller;Hyman M. Schipper;Janet S. Lee;Jack Singer

  • One hundred patients with acute leukemia treated by chemotherapy, total body irradiation, and allogeneic marrow transplantation.

    ED Thomas;CD Buckner;M Banaji;RA Clift

  • Marrow transplantation for acute nonlymphoblastic leukemia in first remission.

    Thomas Ed;Buckner Cd;Clift Ra;Fefer A

  • Marrow Transplantation for the Treatment of Chronic Myelogenous Leukemia

    E D Thomas;R A Clift;A Fefer;F R Appelbaum

  • Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties.

    R G Andrews;J W Singer;I D Bernstein

  • Recombinant Granulocyte-Macrophage Colony-Stimulating Factor after Autologous Bone Marrow Transplantation for Lymphoid Cancer

    John Nemunaitis;John Nemunaitis;John Nemunaitis;Susan N. Rabinowe;Jack W. Singer;Jack W. Singer;Jack W. Singer;Philip J. Bierman

  • Monoclonal antibody 12-8 recognizes a 115-kd molecule present on both unipotent and multipotent hematopoietic colony-forming cells and their precursors

    Robert G. Andrews;Jack W. Singer;Irwin D. Bernstein

  • Graft-versus-host disease and survival in patients with aplastic anemia treated by marrow grafts from HLA-identical siblings. Beneficial effect of a protective environment.

    R Storb;R L Prentice;C D Buckner;R A Clift

  • Autologous transplantation with peripheral blood mononuclear cells collected after administration of recombinant granulocyte stimulating factor

    W Bensinger;J Singer;F Appelbaum;K Lilleby

  • Graft-versus-Host Disease as Adoptive Immunotherapy in Patients with Advanced Hematologic Neoplasms

    K M Sullivan;R Storb;C D Buckner;A Fefer

  • Clonal development, stem-cell differentiation, and clinical remissions in acute nonlymphocytic leukemia

    Philip J. Fialkow;Jack W. Singer;Wendy H. Raskind;John W. Adamson

  • Evidence for a Multistep Pathogenesis of a Myelodysplastic Syndrome

    Wendy H. Raskind;Wendy H. Raskind;Nagendra Tirumali;Nagendra Tirumali;Robert Jacobson;Robert Jacobson;Jack Singer;Jack Singer

  • Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration

    James B. Konopka;Susan M. Watanabe;Jack W. Singer;Steven J. Collins

  • Acute nonlymphocytic leukemia: heterogeneity of stem cell origin.

    Philip J. Fialkow;Jack W. Singer;John W. Adamson;Kalpana Vaidya

  • Use of recombinant human granulocyte-macrophage colony-stimulating factor in autologous marrow transplantation for lymphoid malignancies.

    J Nemunaitis;JW Singer;CD Buckner;R Hill

  • Marrow Transplantation in Thirty Untransfused Patients with Severe Aplastic Anemia

    Storb R;Thomas Ed;Buckner Cd;Clift Ra

  • Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial

    John Mascarenhas;Ronald Hoffman;Moshe Talpaz;Aaron T. Gerds

  • Paclitaxel poliglumex (XYOTAX, CT-2103): a macromolecular taxane.

    Jack W. Singer

  • Pacritinib versus best available therapy for the treatment of myelofibrosis irrespective of baseline cytopenias (PERSIST-1): an international, randomised, phase 3 trial

    Ruben A. Mesa;Alessandro M. Vannucchi;Adam Mead;Miklos Egyed

  • Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapy-naïve advanced non-small cell lung cancer.

    Corey J. Langer;Kenneth J. O’Byrne;Mark A. Socinski;Sergei M. Mikhailov

Frequent Co-Authors

E. Donnall Thomas
E. Donnall Thomas University of Washington
Jean E. Sanders
Jean E. Sanders Fred Hutchinson Cancer Research Center
John W. Adamson
John W. Adamson University of California, San Diego
Frederick R. Appelbaum
Frederick R. Appelbaum Fred Hutchinson Cancer Research Center
Kristine Doney
Kristine Doney Fred Hutchinson Cancer Research Center
Rainer Storb
Rainer Storb Fred Hutchinson Cancer Research Center
John Nemunaitis
John Nemunaitis Gradalis (United States)
Wendy H. Raskind
Wendy H. Raskind University of Washington
Buckner Cd
Buckner Cd National Cancer Institute
William I. Bensinger
William I. Bensinger Fred Hutchinson Cancer Research Center

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