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Patrick Mayeux

Patrick Mayeux

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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
15894
World Ranking
6411
National Ranking
186

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Patrick Mayeux is affiliated with Inserm in France and specializes in the fields of Medicine, Biochemistry, Genetics and Molecular Biology. Their research portfolio includes publications predominantly in Molecular Biology, Physiology, Hematology, Genetics, and Pulmonary and Respiratory Medicine.

Their work covers a range of main topics, including:

  • Erythrocyte Function and Pathophysiology
  • RNA modifications and cancer
  • Acute Myeloid Leukemia Research
  • Epigenetics and DNA Methylation
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Histone Deacetylase Inhibitors Research

They have published several papers in prominent journals. Some of the recent works include:

  • "APR-246 induces early cell death by ferroptosis in acute myeloid leukemia," 2021, Haematologica
  • "p53 activation during ribosome biogenesis regulates normal erythroid differentiation," 2020, Blood
  • "Pairing MCL-1 inhibition with venetoclax improves therapeutic efficiency of BH3-mimetics in AML," 2020, European Journal Of Haematology
  • "Lkb1 suppresses amino acid-driven gluconeogenesis in the liver," 2020, Nature Communications
  • "Comprehensive proteomic analysis of murine terminal erythroid differentiation," 2020, Blood Advances

Frequent co-authors contributing to their research include Emilie-Fleur Gautier, Michaëla Fontenay, François Guillonneau, Didier Bouscary, and Marjorie Leduc.

The most common venues for their publications are:

  • Haematologica
  • Blood
  • European Journal Of Haematology
  • Nature Communications
  • American Journal of Hematology

Best Publications

  • Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin

    Nicole Casadevall;Joelle Nataf;Beatrice Viron;Amir Kolta

  • Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.

    Frédéric Pene;Yann-Erick Claessens;Odile Muller;Franck Viguié

  • Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways

    Jerome Tamburini;Nicolas Chapuis;Valérie Bardet;Sophie Park

  • Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia

    Sophie Park;Nicolas Chapuis;Jérôme Tamburini;Valérie Bardet

  • Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.

    Nathalie Jacque;Anne Marie Ronchetti;Clément Larrue;Clément Larrue;Godelieve Meunier

  • Essential role for the p110δ isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia

    Pierre Sujobert;Valerie Bardet;Pascale Cornillet-Lefebvre;Joel S. Hayflick

  • Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

    Lise Willems;Lise Willems;Nathalie Jacque;Arnaud Jacquel;Nathalie Neveux

  • Biology of erythropoietin

    Catherine Lacombe;Patrick Mayeux

  • Proteasomes Regulate Erythropoietin Receptor and Signal Transducer and Activator of Transcription 5 (STAT5) Activation POSSIBLE INVOLVEMENT OF THE UBIQUITINATED CIS PROTEIN

    Frédérique Verdier;Stany Chrétien;Odile Muller;Paule Varlet

  • Autoantibodies against Erythropoietin in a Patient with Pure Red-Cell Aplasia

    Nicole Casadevall;Evelyne Dupuy;Pascale Molho-Sabatier;Gérard Tobelem

  • PI3K and mTOR Signaling Pathways in Cancer: New Data on Targeted Therapies

    Lise Willems;Jerome Tamburini;Nicolas Chapuis;Catherine Lacombe

  • Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation.

    Didier Bouscary;Frédéric Pene;Yann-Erick Claessens;Odile Muller

  • Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activation.

    S Gobert;S Chretien;F Gouilleux;O Muller

  • High levels of CD34+CD38low/−CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucémies Aiguës et Maladies du Sang (GOELAMS) study

    François Vergez;Alexa S. Green;Jerome Tamburini;Jean-Emmanuel Sarry

  • The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation.

    Alexa S. Green;Alexa S. Green;Nicolas Chapuis;Nicolas Chapuis;Thiago Trovati Maciel;Lise Willems;Lise Willems

  • PI-103, a dual inhibitor of Class IA phosphatidylinositide 3-kinase and mTOR, has antileukemic activity in AML

    S Park;N Chapuis;N Chapuis;V Bardet;J Tamburini;J Tamburini

  • Both proteasomes and lysosomes degrade the activated erythropoietin receptor

    Pierre Walrafen;Frédérique Verdier;Zahra Kadri;Stany Chrétien

  • Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia

    Jerome Tamburini;Jerome Tamburini;Alexa S. Green;Alexa S. Green;Valerie Bardet;Valerie Bardet;Nicolas Chapuis;Nicolas Chapuis

  • Identification of JAK protein tyrosine kinases as signaling molecules for prolactin. Functional analysis of prolactin receptor and prolactin-erythropoietin receptor chimera expressed in lymphoid cells.

    I Dusanter-Fourt;O Muller;A Ziemiecki;P Mayeux

  • Comprehensive Proteomic Analysis of Human Erythropoiesis

    Emilie-Fleur Gautier;Sarah Ducamp;Marjorie Leduc;Virginie Salnot

Frequent Co-Authors

Michaela Fontenay
Michaela Fontenay Institut Cochin
Sylvie Gisselbrecht
Sylvie Gisselbrecht Grenoble Alpes University
Olivier Hermine
Olivier Hermine Necker-Enfants Malades Hospital
Norbert Ifrah
Norbert Ifrah Grenoble Alpes University
Eric Solary
Eric Solary Institut Gustave Roussy
Ivan C. Moura
Ivan C. Moura Inserm : Institut national de la santé et de la recherche médicale
Carmen Garrido
Carmen Garrido University of Burgundy
Christian Recher
Christian Recher Federal University of Toulouse Midi-Pyrénées
Marc Foretz
Marc Foretz Université Paris Cité
Narla Mohandas
Narla Mohandas New York Blood Center

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