World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
45
Citations
15183
World Ranking
16238
National Ranking
897

Overview

Gary N. Parkinson is affiliated with University College London in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with additional work in materials science.

Their subfields of study include molecular biology, materials chemistry, inorganic chemistry, physical and theoretical chemistry, and oncology. Parkinson's research covers several main topics:

  • DNA and nucleic acid chemistry
  • Crystallization and solubility studies
  • Advanced biosensing and bioanalysis techniques
  • RNA and protein synthesis mechanisms
  • X-ray diffraction in crystallography
  • Covalent organic framework applications
  • Metal-organic frameworks: synthesis and applications

Among their recent papers are:

  • Structural insights into i-motif DNA structures in sequences from the insulin-linked polymorphic region, 2024, Nature Communications
  • BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers, 2020, Nucleic Acids Research
  • Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths, 2020, Nucleic Acids Research
  • Structural Motifs at the Telomeres and Their Role in Regulatory Pathways, 2024, Biochemistry
  • A Simple and Sequential Strategy for the Introduction of Complexity and Hierarchy in Hydrogen-Bonded Organic Framework (HOF) Crystals for Environmental Applications, 2024, Angewandte Chemie International Edition

Frequent publication venues for their work include:

  • The Cambridge Structural Database
  • Nucleic Acids Research
  • Nature Communications
  • Biochemistry
  • Angewandte Chemie International Edition

Frequent collaborators in Parkinson's research are Shozeb Haider, Alexander E. Clout, Asma B. M. Buanz, Yuying Pang, and Wing-Mei Tsui, each coauthoring multiple publications with them.

Best Publications

  • Quadruplex DNA: sequence, topology and structure

    Sarah Burge;Gary N. Parkinson;Pascale Hazel;Alan K. Todd

  • Crystal structure of parallel quadruplexes from human telomeric DNA.

    Gary N. Parkinson;Michael P. H. Lee;Stephen Neidle

  • Putative DNA Quadruplex Formation within the Human c-kit Oncogene

    Sarah Rankin;Anthony P. Reszka;Julian Huppert;Mire Zloh

  • The application of DNA and RNA G-quadruplexes to therapeutic medicines

    Gavin W. Collie;Gary N. Parkinson

  • The structure of telomeric DNA

    Stephen Neidle;Gary N Parkinson

  • Structural basis for binding of porphyrin to human telomeres.

    Gary N. Parkinson;Ragini Ghosh;Stephen Neidle

  • Crystal structure of the potassium form of an Oxytricha nova G-quadruplex.

    Shozeb Haider;Gary N. Parkinson;Stephen Neidle

  • Structure of the CAP-DNA complex at 2.5 angstroms resolution: a complete picture of the protein-DNA interface.

    Gary Parkinson;Christopher Wilson;Angelo Gunasekera;Yon W. Ebright

  • Structure of a G-quadruplex-Ligand Complex

    Shozeb M. Haider;Gary N. Parkinson;Stephen Neidle

  • Structural Basis of DNA Quadruplex Recognition by an Acridine Drug

    Nancy H Campbell;Gary N Parkinson;Anthony P Reszka;Stephen Neidle

  • New parameters for the refinement of nucleic acid-containing structures.

    G. Parkinson;J. Vojtechovsky;L. Clowney;A. T. Brünger

  • A new class of symmetric bisbenzimidazole-based DNA minor groove-binding agents showing antitumor activity.

    John Mann;Anne Baron;Yaw Opoku-Boahen;Eric Johansson

  • A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex

    Gavin W. Collie;Shozeb M. Haider;Stephen Neidle;Gary N. Parkinson

  • Structural basis for telomeric g-quadruplex targeting by naphthalene diimide ligands.

    Gavin W. Collie;Rossella Promontorio;Sonja M. Hampel;Marialuisa Micco

  • Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes.

    Nancy H. Campbell;Nurul Huda Abd Karim;Gary N. Parkinson;Mekala Gunaratnam

  • G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome.

    Roberto Simone;Pietro Fratta;Stephen Neidle;Gary N. Parkinson

  • Molecular Dynamics and Principal Components Analysis of Human Telomeric Quadruplex Multimers

    Shozeb Haider;Gary N. Parkinson;Stephen Neidle

  • Topology Conservation and Loop Flexibility in Quadruplex-Drug Recognition : Crystal Structures of Inter-and Intramolecular Telomeric DNA Quadruplex-Drug Complexes

    Gary N. Parkinson;Francisco Cuenca;Stephen Neidle

  • G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

    Roberto Simone;Rubika Balendra;Rubika Balendra;Thomas G. Moens;Thomas G. Moens;Elisavet Preza

  • Quadruplex DNA crystal structures and drug design.

    Stephen Neidle;Gary N. Parkinson

  • Crystal structure of FMN-dependent nitroreductase from Escherichia coli B: a prodrug-activating enzyme.

    Gary N. Parkinson;Jane V. Skelly;Stephen Neidle

  • Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation

    Dengguo Wei;Gary N. Parkinson;Anthony P. Reszka;Stephen Neidle

  • Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form.

    Eric Johansson;Gary N Parkinson;William A Denny;Stephen Neidle

Frequent Co-Authors

Stephen Neidle
Stephen Neidle University College London
Helen M. Berman
Helen M. Berman Rutgers, The State University of New Jersey
Richard H. Ebright
Richard H. Ebright Rutgers, The State University of New Jersey
Simon Gaisford
Simon Gaisford University College London
Ramon Vilar
Ramon Vilar Imperial College London
David E. Thurston
David E. Thurston King's College London
John E. Ladbury
John E. Ladbury University of Leeds
Linda Partridge
Linda Partridge Max Planck Society
Jonathan A. Fletcher
Jonathan A. Fletcher Brigham and Women's Hospital
Richard R. Copley
Richard R. Copley Wellcome Centre for Human Genetics

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring online degrees related to Chemistry can open doors to diverse career opportunities in fields like criminal justice, paralegal studies, and pharmaceutical sales. When considering education options, it’s important to be aware of the cost of criminal justice degree programs, as tuition and fees vary significantly across institutions.

For those interested in foundational qualifications, the best online criminal justice associate degree programs offer flexible learning options that can complement a Chemistry background, especially in forensic science or regulatory roles.

Another viable path includes paralegal careers, where an associate degree is often sufficient. Understanding the paralegal salary associate's degree trends can help in evaluating long-term financial prospects while leveraging strong analytical skills gained through Chemistry studies.

For those leaning toward the healthcare sector, becoming a pharmaceutical sales representative is a dynamic option. Knowing how much do pharmaceutical reps make provides insight into the earning potential and career growth in this field that heavily relies on scientific knowledge.

Best Scientists Citing Gary N. Parkinson

Trending Scientists

Recently Published Articles