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Chemistry

D-Index
62
Citations
18332
World Ranking
8700
National Ranking
63

Molecular Biology

D-Index
64
Citations
18625
World Ranking
1721
National Ranking
12

Research.com Recognitions

  • 2014 - Fellow of American Physical Society (APS) Citation For his significant contributions in understanding noncanonical nucleic acid motifs, particularly the imotif and the Gquadruplex by developing novel NMR techniques

Overview

Anh Tuân Phan is affiliated with Nanyang Technological University in Singapore and has a research focus primarily within Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology. Their work extends into subfields including Ecology, Immunology, Electrical and Electronic Engineering, and Cancer Research.

Their research topics cover a variety of scientific areas such as:

  • Advanced biosensing and bioanalysis techniques
  • DNA and Nucleic Acid Chemistry
  • Bacteriophages and microbial interactions
  • RNA and protein synthesis mechanisms
  • RNA Interference and Gene Delivery
  • Extracellular vesicles in disease
  • RNA modifications and cancer

Multiple publications by Anh Tuân Phan have appeared in journals and venues that include:

  • Chemical Communications
  • Nucleic Acids Research
  • Circulation
  • Biochemical and Biophysical Research Communications
  • bioRxiv (Cold Spring Harbor Laboratory)

Some examples of recent significant papers authored or co-authored by Anh Tuân Phan are:

  • Post-translational formation of strained cyclophanes in bacteria (2020, Nature Chemistry)
  • The biofilm matrix scaffold of Pseudomonas aeruginosa contains G-quadruplex extracellular DNA structures (2021, npj Biofilms and Microbiomes)
  • Extracellular Vesicle-Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart (2023, Circulation)
  • Synergistic effect for the degradation of tetracycline by rGO-Co3O4 assisted persulfate activation (2021, Journal of Physics and Chemistry of Solids)
  • G4-PROTAC: targeted degradation of a G-quadruplex binding protein (2021, Chemical Communications)

Frequent collaborators with whom Anh Tuân Phan has published include:

  • Fernaldo Richtia Winnerdy
  • Kah Wai Lim
  • Susmita Sahoo
  • Xisheng Li
  • Nikhil Raisinghani

In recognition of their work, Anh Tuân Phan received the Fellow of the American Physical Society (APS) award in 2014 for contributions to understanding noncanonical nucleic acid motifs, including the imotif and G-quadruplex, with the development of novel NMR techniques.

Best Publications

  • Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

    Dinshaw J. Patel;Anh Tuân Phan;Vitaly Kuryavyi

  • Structure of the Human Telomere in K+ Solution: An Intramolecular (3 + 1) G-Quadruplex Scaffold

    Kim Ngoc Luu;Anh Tuân Phan;Vitaly Kuryavyi;Laurent Lacroix

  • Following G-quartet formation by UV-spectroscopy

    Jean-Louis Mergny;Anh-Tuan Phan;Laurent Lacroix

  • Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs

    Alexander Serganov;Yu Ren Yuan;Olga Pikovskaya;Anna Polonskaia

  • Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter.

    Anh Tuân Phan;Yasha S. Modi;Dinshaw J. Patel

  • Human telomeric G-quadruplex: structures of DNA and RNA sequences.

    Anh Tuân Phan

  • Human telomeric DNA: G‐quadruplex, i‐motif and Watson–Crick double helix

    Anh Tuân Phan;Jean‐Louis Mergny

  • Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

    Anh Tuân Phan;Vitaly Kuryavyi;Hai Yan Gaw;Dinshaw J Patel

  • Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution

    Anh Tuân Phan;Vitaly Kuryavyi;Kim Ngoc Luu;Dinshaw J. Patel

  • Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers

    Kah Wai Lim;Samir Amrane;Serge Bouaziz;Weixin Xu

  • Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.

    Anh Tuân Phan;Vitaly Kuryavyi;Sarah Burge;Stephen Neidle

  • Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch.

    Alexander Serganov;Anna Polonskaia;Anh Tuân Phan;Ronald R. Breaker

  • NMR spectroscopy of G-quadruplexes.

    Michael Adrian;Brahim Heddi;Anh Tuân Phan

  • Structure of human telomeric DNA in crowded solution.

    Brahim Heddi;Anh Tuân Phan

  • Different loop arrangements of intramolecular human telomeric (3+1) G-quadruplexes in K+ solution

    Anh Tuân Phan;Kim Ngoc Luu;Dinshaw J. Patel

  • Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics.

    Anh Tuân Phan;Dinshaw J. Patel

  • Bulges in G-quadruplexes: broadening the definition of G-quadruplex-forming sequences.

    Vineeth Thachappilly Mukundan;Anh Tuân Phan

  • DNA architecture: from G to Z.

    Anh Tuân Phan;Vitaly Kuryavyi;Dinshaw J Patel

  • An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase

    Anh Tuân Phan;Vitaly Kuryavyi;Jin-Biao Ma;Aurélie Faure

  • Structure of Propeller-Type Parallel-Stranded RNA G-Quadruplexes, Formed by Human Telomeric RNA Sequences in K+ Solution

    Herry Martadinata;Anh Tuân Phan

Frequent Co-Authors

Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Yves Mechulam
Yves Mechulam École Polytechnique
Valentina Tereshko
Valentina Tereshko University of Chicago
Ronald Micura
Ronald Micura University of Innsbruck
Andres Jäschke
Andres Jäschke Heidelberg University
Alexander A. Voityuk
Alexander A. Voityuk Institució Catalana de Recerca i Estudis Avançats
Kazuo Nagasawa
Kazuo Nagasawa Tokyo University of Agriculture and Technology
Ronald R. Breaker
Ronald R. Breaker Yale University
Robert B. Darnell
Robert B. Darnell Rockefeller University

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