D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 42 Citations 4,931 100 World Ranking 17347 National Ranking 798

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Biochemistry, Escherichia coli, Transfer RNA, Mutant and Stereochemistry. His study in Biochemistry concentrates on Translation, Methionine—tRNA ligase and Eukaryotic translation. Yves Mechulam interconnects Nucleic acid sequence, Crystal structure and Enzyme in the investigation of issues within Escherichia coli.

Yves Mechulam regularly links together related areas like Nonsense mutation in his Transfer RNA studies. His Mutant research is multidisciplinary, incorporating elements of Mutation and RNA. His studies deal with areas such as Crystallography, Helix and DNA nanotechnology, DNA as well as Stereochemistry.

His most cited work include:

  • Methionine as translation start signal: A review of the enzymes of the pathway in Escherichia coli (183 citations)
  • Capturing the mutational landscape of the beta-lactamase TEM-1. (164 citations)
  • Disruption of the gene for Met-tRNA(fMet) formyltransferase severely impairs growth of Escherichia coli. (140 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Transfer RNA, Biochemistry, Escherichia coli, Stereochemistry and Enzyme. His biological study spans a wide range of topics, including Amino acid, Ribosome, Initiation factor and Mutant. His studies in Methionine, Translation, Eukaryotic translation, Methionine—tRNA ligase and Protein biosynthesis are all subfields of Biochemistry research.

His Escherichia coli study incorporates themes from Nucleic acid sequence, Mutagenesis and Nucleotide. His Stereochemistry research includes themes of Crystallography, Helix, Rossmann fold, Sulfolobus solfataricus and Protein structure. His studies in Enzyme integrate themes in fields like Moiety, Site-directed mutagenesis and Bacteria.

He most often published in these fields:

  • Transfer RNA (57.84%)
  • Biochemistry (55.88%)
  • Escherichia coli (28.43%)

What were the highlights of his more recent work (between 2016-2021)?

  • Transfer RNA (57.84%)
  • Stereochemistry (27.45%)
  • G-quadruplex (7.84%)

In recent papers he was focusing on the following fields of study:

Yves Mechulam mainly focuses on Transfer RNA, Stereochemistry, G-quadruplex, Amino acid and Eukaryotic translation. The study incorporates disciplines such as Mutant and Ribosomal protein in addition to Transfer RNA. His Stereochemistry research is multidisciplinary, relying on both Nucleic acid and DHX36, Helicase.

In his research on the topic of G-quadruplex, Polymorphism, Crystallography and Crystal structure is strongly related with A-DNA. His study on Amino acid is covered under Biochemistry. The various areas that Yves Mechulam examines in his Eukaryotic translation study include Ribosome, 30S, Pyrococcus abyssi and Start codon.

Between 2016 and 2021, his most popular works were:

  • A Minimal Sequence for Left-Handed G-Quadruplex Formation. (18 citations)
  • NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. (12 citations)
  • The trimeric coiled-coil HSBP1 protein promotes WASH complex assembly at centrosomes (12 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Yves Mechulam mostly deals with DNA, G-quadruplex, Ribosomal RNA, Stereochemistry and Initiation factor. His research in Ribosomal RNA intersects with topics in Ribosome, Translation, Eukaryotic translation, Messenger RNA and Computational biology. His Stereochemistry research is multidisciplinary, incorporating perspectives in Aminoacyl tRNA synthetase, Serine, Rossmann fold, DNA ligase and Subfamily.

Aminoacyl tRNA synthetase is a subfield of Transfer RNA that Yves Mechulam investigates. With his scientific publications, his incorporates both Transfer RNA and Partition. His research integrates issues of Ribosomal protein, Pyrococcus abyssi, 30S, Open reading frame and Start codon in his study of Initiation factor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Methionine as translation start signal: A review of the enzymes of the pathway in Escherichia coli

T. Meinnel;Y. Mechulam;S. Blanquet.
Biochimie (1993)

287 Citations

Capturing the mutational landscape of the beta-lactamase TEM-1.

Hervé Jacquier;Hervé Jacquier;André Birgy;André Birgy;Hervé Le Nagard;Yves Mechulam.
Proceedings of the National Academy of Sciences of the United States of America (2013)

216 Citations

Disruption of the gene for Met-tRNA(fMet) formyltransferase severely impairs growth of Escherichia coli.

J M Guillon;Y Mechulam;J M Schmitter;S Blanquet.
Journal of Bacteriology (1992)

204 Citations

Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet.

Emmanuelle Schmitt;Michel Panvert;Sylvain Blanquet;Yves Mechulam.
The EMBO Journal (1998)

156 Citations

Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features.

Yves Mechulam;Emmanuelle Schmitt;Laurent Maveyraud;Charles Zelwer.
Journal of Molecular Biology (1999)

137 Citations

The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors

Emmanuelle Schmitt;Sylvain Blanquet;Yves Mechulam.
The EMBO Journal (2002)

128 Citations

Nucleotides of tRNA governing the specificity of Escherichia coli methionyl-tRNAfMet formyltransferase

Jean-Michel Guillon;Thierry Meinnel;Yves Mechulam;Christine Lazennec.
Journal of Molecular Biology (1992)

125 Citations

Discovery of Escherichia coli methionyl-tRNA synthetase mutants for efficient labeling of proteins with azidonorleucine in vivo

I. Caglar Tanrikulu;Emmanuelle Schmitt;Yves Mechulam;William A. Goddard.
Proceedings of the National Academy of Sciences of the United States of America (2009)

124 Citations

Identification of an amino acid region supporting specific methionyl-tRNA synthetase: tRNA recognition.

Patrice Mellot;Yves Mechulam;Daniel Le Corre;Sylvain Blanquet.
Journal of Molecular Biology (1989)

111 Citations

Structure of a left-handed DNA G-quadruplex

Wan Jun Chung;Brahim Heddi;Emmanuelle Schmitt;Kah Wai Lim.
Proceedings of the National Academy of Sciences of the United States of America (2015)

106 Citations

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