Andre Mitschler

Overview

Best Publications

• The Crystal Structure of the Nuclear Receptor for Vitamin D Bound to Its Natural Ligand

  N. Rochel;J.M. Wurtz;A. Mitschler;B. Klaholz

  982
  Citations

• Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp)

  M Ruff;S Krishnaswamy;M Boeglin;A Poterszman

  866
  Citations

• Transmembrane signaling across the ligand-gated FhuA receptor: crystal structures of free and ferrichrome-bound states reveal allosteric changes.

  Kaspar P Locher;Bernard Rees;Ralf Koebnik;André Mitschler

  708
  Citations

• Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

  Denise Martinez-Zapien;Francesc Xavier Ruiz;Juline Poirson;André Mitschler

  508
  Citations

• Crystal structure of the human RXRα ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

  Pascal F. Egea;André Mitschler;Natacha Rochel;Marc Ruff

  454
  Citations

• Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A.

  E.I. Howard;R. Sanishvili;R.E. Cachau;A. Mitschler

  371
  Citations

• The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.

  J Cavarelli;G Eriani;B Rees;M Ruff

  363
  Citations

• A `specificity'pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.

  A Urzhumtsev;F Tête-Favier;A Mitschler;J Barbanton

  308
  Citations

• Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor

  Isabelle M. L. Billas;Thomas Iwema;Jean-Marie Garnier;André Mitschler

  298
  Citations

• Generation and trapping of terminal phosphinidene complexes. Synthesis and x-ray crystal structure of stable phosphirene complexes

  Angela Marinetti;Francois Mathey;Jean Fischer;Andre Mitschler

  291
  Citations

• Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

  G. Tocchini-Valentini;N. Rochel;J. M. Wurtz;A. Mitschler

  253
  Citations

• Palladium(II) tert-butyl peroxide carboxylates. New reagents for the selective oxidation of terminal olefins to methyl ketones. The role of peroxymetalation in selective oxidative processes

  Hubert Mimoun;Robert Charpentier;Andre Mitschler;Jean Fischer

  239
  Citations

• Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center.

  Laurent Brino;Alexandre Urzhumtsev;Marc Mousli;Christian Bronner

  214
  Citations

• Molecular Recognition of Agonist Ligands by RXRs

  Pascal F. Egea;André Mitschler;Dino Moras

  214
  Citations

• Conformational adaptation of agonists to the human nuclear receptor RAR gamma.

  B.P. Klaholz;J.-P. Renaud;A. Mitschler;C. Zusi

  205
  Citations

• Complexes of functional phosphines. 4. Coordination properties of (diphenylphosphino)acetonitrile, ethyl (diphenylphosphino)acetate and corresponding carbanions. Characterization of a new facile reversible carbon dioxide insertion into palladium(II) complexes

  Pierre Braunstein;Dominique Matt;Yves Dusausoy;Jean Fischer

  204
  Citations

• 1,1'-Diphosphaferrocenes. Synthesis, basic chemistry, and structure

  Guillaume De Lauzon;Bernard Deschamps;Jean Fischer;Francois Mathey

  190
  Citations

• Crystal structure of histidyl-tRNA synthetase from Escherichia coli complexed with histidyl-adenylate.

  J. G. Arnez;D. C. Harris;A. Mitschler;B. Rees

  188
  Citations

• Structural basis for isotype selectivity of the human retinoic acid nuclear receptor.

  Bruno P Klaholz;André Mitschler;Dino Moras

  171
  Citations

• Electronic structure of chromium hexacarbonyl at liquid nitrogen temperature. 2. Experimental study (x-ray and neutron diffraction) of .sigma. and .pi. bonding

  Bernard Rees;Andre Mitschler

  166
  Citations