His scientific interests lie mostly in Biochemistry, Pharmacology, Drug discovery, Transporter and Stereochemistry. The study incorporates disciplines such as Biophysics and Cell biology in addition to Biochemistry. His research in Pharmacology is mostly concerned with Pharmacokinetics.
His work in Pharmacokinetics covers topics such as In vivo which are related to areas like In vitro. His work carried out in the field of Drug discovery brings together such families of science as ADME and Drug. His study looks at the intersection of Bioinformatics and topics like Drug development with SLC47A1, Organic anion-transporting polypeptide, New drug application and Clinical trial.
Peter W. Swaan mostly deals with Biochemistry, Transporter, Pharmacology, Cell biology and Computational biology. In his work, Dendrimer, Poly and Amidoamine is strongly intertwined with Biophysics, which is a subfield of Biochemistry. His Transporter research is multidisciplinary, incorporating elements of Pharmacophore, Quantitative structure–activity relationship, Efflux and In silico.
The In silico study which covers Drug discovery that intersects with ADME. His Pharmacology research includes elements of Virtual screening and Toxicity. His biological study spans a wide range of topics, including Endocytic cycle, Receptor, Endocytosis and Drug delivery.
Peter W. Swaan mainly focuses on Transporter, Pharmacology, Biochemistry, Pharmacy and Bile acid. His research integrates issues of Efflux and Glycosylation in his study of Transporter. His study in Drug and DrugBank are all subfields of Pharmacology.
His Drug study which covers Toxicity that intersects with Carrier protein, Disease, Bioinformatics and Drug metabolism. His research investigates the connection between Biochemistry and topics such as Monoamine transporter that intersect with problems in Membrane, Plasma membrane monoamine transporter and Organic cation transport. His Multidrug Resistance-Associated Proteins research incorporates elements of Pharmacokinetics and Liver injury.
Peter W. Swaan spends much of his time researching Transporter, Pharmacology, Cholestasis, Multidrug Resistance-Associated Proteins and Bile Salt Export Pump. His Transporter study is related to the wider topic of Biochemistry. His work on Organic cation transport proteins, Plasma membrane monoamine transporter and Organic cation transport as part of general Biochemistry research is often related to Lopinavir, thus linking different fields of science.
His study in the field of Drug and Drug metabolism also crosses realms of Extramural. His study in Drug is interdisciplinary in nature, drawing from both Carrier protein, Disease, Toxicity and Bioinformatics. Within one scientific family, Peter W. Swaan focuses on topics pertaining to Pharmacokinetics under Cholestasis, and may sometimes address concerns connected to Pharmaceutical sciences.
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Membrane transporters in drug development.
Kathleen M. Giacomini;Shiew Mei Huang;Donald J. Tweedie;Leslie Z. Benet.
Nature Reviews Drug Discovery (2010)
ENDOCYTIC MECHANISMS FOR TARGETED DRUG DELIVERY
Lisa M. Bareford;Peter W. Swaan.
Advanced Drug Delivery Reviews (2007)
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration.
Savita Khanna;Sashwati Roy;Hoon Ryu;Praveen Bahadduri.
Journal of Biological Chemistry (2003)
Camptothecins: a review of their chemotherapeutic potential.
Hulya Ulukan;Peter W. Swaan.
Progress in predicting human ADME parameters in silico.
Sean Ekins;Chris L Waller;Peter W Swaan;Gabriele Cruciani.
Journal of Pharmacological and Toxicological Methods (2000)
Surface Acetylation of Polyamidoamine (PAMAM) Dendrimers Decreases Cytotoxicity while Maintaining Membrane Permeability
Rohit B. Kolhatkar;Kelly M. Kitchens;Peter W. Swaan;Hamidreza Ghandehari.
Bioconjugate Chemistry (2007)
Microfabricated porous silicon particles enhance paracellular delivery of insulin across intestinal Caco-2 cell monolayers.
Amy B. Foraker;Rob J. Walczak;Michael H. Cohen;Tony A. Boiarski.
Pharmaceutical Research (2003)
Design, synthesis, cytoselective toxicity, structure-activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells.
Hongyu Zhou;Shuhong Wu;Shumei Zhai;Aifeng Liu.
Journal of Medicinal Chemistry (2008)
Transport of Poly(Amidoamine) Dendrimers across Caco-2 Cell Monolayers: Influence of Size, Charge and Fluorescent Labeling
Kelly M. Kitchens;Rohit B. Kolhatkar;Peter W. Swaan;Natalie D. Eddington.
Pharmaceutical Research (2006)
Endocytosis and interaction of poly (amidoamine) dendrimers with Caco-2 cells.
Kelly M. Kitchens;Amy B. Foraker;Rohit B. Kolhatkar;Peter W. Swaan.
Pharmaceutical Research (2007)
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