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Chemistry

D-Index
82
Citations
22189
World Ranking
3130
National Ranking
1039

Biology and Biochemistry

D-Index
84
Citations
22167
World Ranking
3374
National Ranking
1697

Overview

Duane D. Miller is affiliated with the University of Tennessee Health Science Center in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, reflecting a focus on understanding complex biological processes and disease mechanisms.

The main areas of study within their work include Molecular Biology, Organic Chemistry, Oncology, Pathology and Forensic Medicine, and Pulmonary and Respiratory Medicine. Their research contributions frequently address topics such as synthesis and biological activity, cancer mechanisms and therapy, cancer therapeutics and mechanisms, protein degradation and inhibitors, chromatin remodeling and cancer, prostate cancer treatment and research, and HER2/EGFR in cancer research.

Duane D. Miller has published extensively in a number of scientific journals. Their frequent publication venues include the Journal of Medicinal Chemistry, Cancer Research, International Journal of Molecular Sciences, Cancer Letters, and Pharmaceuticals.

Recent papers authored or co-authored by Duane D. Miller include:

  • Recent Progress on Tubulin Inhibitors with Dual Targeting Capabilities for Cancer Therapy, 2021, Journal of Medicinal Chemistry
  • Molecular interactions at the colchicine binding site in tubulin: An X-ray crystallography perspective, 2021, Drug Discovery Today
  • An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer, 2021, International Journal of Molecular Sciences
  • Recent Advances in Elucidating Paclitaxel Resistance Mechanisms in Non-small Cell Lung Cancer and Strategies to Overcome Drug Resistance, 2020, Current Medicinal Chemistry
  • Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents, 2021, Journal of Medicinal Chemistry

Collaborations are an important aspect of Duane D. Miller's work. Frequent co-authors include Wěi Li, Dong-Jin Hwang, Hao Chen, Lawrence M. Pfeffer, and Yali He, indicating ongoing research partnerships that contribute to the interdisciplinary nature of their studies.

Best Publications

  • An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site

    Yan Lu;Jianjun Chen;Min Xiao;Wei Li

  • Structural basis for antagonism and resistance of bicalutamide in prostate cancer.

    Casey E. Bohl;Wenqing Gao;Duane D. Miller;Charles E. Bell

  • Emerging Trends in Oral Delivery of Peptide and Protein Drugs

    Ram I. Mahato;Ajit S. Narang;Laura Thoma;Duane D. Miller

  • Discovery of Nonsteroidal Androgens

    James T. Dalton;Arnab Mukherjee;Zixin Zhu;Leonid Kirkovsky

  • Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's disease.

    Michael S. Wolfe;Joseph De Los Angeles;Joseph De Los Angeles;Duane D. Miller;Weiming Xia

  • Novel branched poly(ethylenimine)-cholesterol water-soluble lipopolymers for gene delivery

    Dong An Wang;Ajit S. Narang;Malak Kotb;A. Osama Gaber

  • Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography-mass spectrometry.

    Daniel L. Baker;Dominic M. Desiderio;Duane D. Miller;Betsy Tolley

  • Selective androgen receptor modulators in preclinical and clinical development

    Ramesh K. Narayanan;Michael L. Mohler;Casey E. Bohl;Duane D Miller

  • Favorable effects of weak acids on negative-ion electrospray ionization mass spectrometry.

    Zengru Wu;Wenqing Gao;Mitch A. Phelps;Di Wu

  • Structural basis for accommodation of nonsteroidal ligands in the androgen receptor.

    Casey E. Bohl;Duane D. Miller;Jiyun Chen;Charles E. Bell

  • Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit.

    Michael L. Mohler;Casey E. Bohl;Amanda Jones;Christopher C. Coss

  • Selective Androgen Receptor Modulator Treatment Improves Muscle Strength and Body Composition and Prevents Bone Loss in Orchidectomized Rats

    Wenqing Gao;Peter J. Reiser;Christopher C. Coss;Mitch A. Phelps

  • Synthesis and antiproliferative activity of 2-aryl-4-oxo-thiazolidin-3-yl-amides for prostate cancer.

    Veeresa Gududuru;Eunju Hurh;James T. Dalton;Duane D. Miller

  • Pharmacodynamics of Selective Androgen Receptor Modulators

    Donghua Yin;Wenqing Gao;Jeffrey D. Kearbey;Huiping Xu

  • Discovery of 4-substituted methoxybenzoyl-aryl-thiazole as novel anticancer agents: synthesis, biological evaluation, and structure-activity relationships.

    Yan Lu;Chien-Ming Li;Zhao Wang;Charles R. Ross

  • Selective androgen receptor modulators and methods of use thereof

    James T. Dalton;Duane D. Miller;Karen A. Veverka

  • Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy.

    Hao Chen;Zongtao Lin;Kinsie E Arnst;Duane D Miller

  • Design, synthesis, and biological characterization of metabolically stable selective androgen receptor modulators.

    Craig A. Marhefka;Wenqing Gao;Kiwon Chung;Juhyun Kim

  • Comparison of the Pharmacological Effects of a Novel Selective Androgen Receptor Modulator, the 5α-Reductase Inhibitor Finasteride, and the Antiandrogen Hydroxyflutamide in Intact Rats: New Approach for Benign Prostate Hyperplasia

    Wenqing Gao;Jeffrey D. Kearbey;Vipin A. Nair;Kiwon Chung

  • Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors.

    Károly Liliom;Guoping Sun;Moritz Bünemann;Tamás Virág

  • The role of vitamin D in cancer prevention

    Rachel A. Ness;Duane D. Miller;Wei Li

Frequent Co-Authors

James T. Dalton
James T. Dalton St. Jude Children's Research Hospital
Wei Li
Wei Li University of Tennessee Health Science Center
Gabor Tigyi
Gabor Tigyi University of Tennessee Health Science Center
Andrzej Slominski
Andrzej Slominski University of Alabama at Birmingham
Robert C. Tuckey
Robert C. Tuckey University of Western Australia
Arnold E. Postlethwaite
Arnold E. Postlethwaite University of Tennessee Health Science Center
Yuko Fujiwara
Yuko Fujiwara Harvard University
Jordan K. Zjawiony
Jordan K. Zjawiony University of Mississippi
Ram I. Mahato
Ram I. Mahato University of Nebraska Medical Center
Lawrence M. Pfeffer
Lawrence M. Pfeffer University of Tennessee Health Science Center

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