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Chemistry

D-Index
45
Citations
6736
World Ranking
16532
National Ranking
4108

Overview

Jordan K. Zjawiony is affiliated with the University of Mississippi in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these domains, subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Pharmacology, Plant Science, and Cancer Research are notable areas of focus.

Their research topics cover a range of subjects related to molecular mechanisms and natural compounds, including:

  • Neuropeptides and Animal Physiology
  • Pharmacological Receptor Mechanisms and Effects
  • Phytochemistry and Biological Activities
  • Sesquiterpenes and Asteraceae Studies
  • Plant Toxicity and Pharmacological Properties
  • Receptor Mechanisms and Signaling
  • Natural product bioactivities and synthesis

Jordan K. Zjawiony has contributed to multiple scientific publications. Select recent papers include:

  • 6,5-Fused Ring, C2-Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects, 2022, ChemMedChem
  • Rotenoids and Other Specialized Metabolites from the Roots of Mirabilis multiflora: Opioid and Cannabinoid Receptor Radioligand Binding Affinities, 2021, Journal of Natural Products
  • Involvement of the Benzodiazepine Site in the Anticonvulsant Activity of Tapinanthus globiferus against Pentylenetetrazole-induced Seizures in Mice, 2020, Planta Medica
  • Critical interactions between opioid and cannabinoid receptors during tolerance and physical dependence development to opioids in the murine gastrointestinal tract: proof of concept, 2021, Pharmacological Reports
  • Bis-spirolabdane Diterpenoids from Leonotis nepetaefolia, 2020, OPAL (Open@LaTrobe) (La Trobe University)

Collaboration is a significant aspect of Zjawiony's work, with frequent co-authors including:

  • Bryan L. Roth
  • Daneel Ferreira
  • R. V. Bikbulatov
  • Prabhakar R. Polepally
  • Adam W. Keasling

Zjawiony's research has been published extensively in venues such as:

  • UNC Libraries
  • ChemMedChem
  • Journal of Natural Products
  • Planta Medica
  • Pharmacological Reports

Best Publications

  • Biologically active compounds from Aphyllophorales (polypore) fungi.

    Jordan K. Zjawiony

  • Novel activities of CYP11A1 and their potential physiological significance

    Andrzej T. Slominski;Wei Li;Tae Kang Kim;Igor Semak

  • A novel pathway for sequential transformation of 7‐dehydrocholesterol and expression of the P450scc system in mammalian skin

    Andrzej Slominski;Jordan Zjawiony;Jacobo Wortsman;Igor Semak

  • Marine Natural Products as Antituberculosis Agents

    Khalid A El Sayed;Piotr Bartyzel;Xiaoyu Shen;Tony L Perry

  • Salvinorin A, an active component of the hallucinogenic sage salvia divinorum is a highly efficacious kappa-opioid receptor agonist: structural and functional considerations.

    Charles Chavkin;Sumit Sud;Wenzhen Jin;Jeremy Stewart

  • The G Protein–Biased κ -Opioid Receptor Agonist RB-64 Is Analgesic with a Unique Spectrum of Activities In Vivo

    Kate L. White;J. Elliott Robinson;Hu Zhu;Jeffrey F. DiBerto

  • The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism

    Andrzej Slominski;Igor Semak;Jordan Zjawiony;Jacobo Wortsman

  • Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.

    Andrzej T. Slominski;Zorica Janjetovic;Brian E. Fuller;Michal A. Zmijewski

  • Identification of novel functionally selective κ-opioid receptor scaffolds.

    Kate L. White;Alex P. Scopton;Marie Laure Rives;Ruslan V. Bikbulatov

  • Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc

    Robert C. Tuckey;Wei Li;Jordan K. Zjawiony;Michal A. Zmijewski

  • Anti-inflammatory Coumarin and Benzocoumarin Derivatives from Murraya alata

    Hai-Ning Lv;Shu Wang;Ke-Wu Zeng;Jun Li

  • An alternative pathway of vitamin D2 metabolism Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2

    Andrzej Slominski;Igor Semak;Jacobo Wortsman;Jordan Zjawiony

  • Copyrine alkaloids: synthesis, spectroscopic characterization, and antimycotic/antimycobacterial activity of A- and B-ring-functionalized sampangines.

    John R. Peterson;Jordan K. Zjawiony;Shihchih Liu;Charles D. Hufford

  • Aplysinopsins--marine indole alkaloids: chemistry, bioactivity and ecological significance.

    Dobroslawa Bialonska;Jordan K. Zjawiony

  • Identification of the Molecular Mechanisms by Which the Diterpenoid Salvinorin A Binds to κ-Opioid Receptors†

    Feng Yan;Philip D. Mosier;Richard B. Westkaemper;Jeremy Stewart

  • Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin.

    Andrzej T. Slominski;Michal A. Zmijewski;Igor Semak;Trevor Sweatman

  • Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.

    R Capasso;F Borrelli;M G Cascio;G Aviello

  • Cytochromes p450 and skin cancer: role of local endocrine pathways.

    Andrzej T. Slominski;Michal A. Zmijewski;Igor Semak;Blazej Zbytek

  • Phytochemical Investigation of Cycas circinalis and Cycas revoluta Leaflets: Moderately Active Antibacterial Biflavonoids

    Abeer Moawad;Mona Hetta;Jordan K. Zjawiony;Melissa R. Jacob

  • Salvinorin A Has Antiinflammatory and Antinociceptive Effects in Experimental Models of Colitis in Mice Mediated by KOR and CB1 Receptors

    Jakub Fichna;Michael Dicay;Kevin Lewellyn;Anna Janecka

Frequent Co-Authors

Andrzej Slominski
Andrzej Slominski University of Alabama at Birmingham
Wei Li
Wei Li University of Tennessee Health Science Center
Robert C. Tuckey
Robert C. Tuckey University of Western Australia
Bryan L. Roth
Bryan L. Roth University of North Carolina at Chapel Hill
Duane D. Miller
Duane D. Miller University of Tennessee Health Science Center
Jun Li
Jun Li Applied Biological Materials (Canada)
Daneel Ferreira
Daneel Ferreira University of Mississippi
Angelo A. Izzo
Angelo A. Izzo University of Naples Federico II
Frank R. Fronczek
Frank R. Fronczek Louisiana State University
Jacobo Wortsman
Jacobo Wortsman Southern Illinois University School of Medicine

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