What is he best known for?
The fields of study he is best known for:
Wei Li mainly focuses on Biochemistry, Cholesterol side-chain cleavage enzyme, Stereochemistry, Internal medicine and Biological activity.
His study in Metabolism, Lumisterol, Cholecalciferol, Vitamin and Hydroxylation is carried out as part of his studies in Biochemistry.
His studies in Cholesterol side-chain cleavage enzyme integrate themes in fields like HaCaT, Pregnenolone, Ergosterol and Corticotropin-releasing hormone.
As part of the same scientific family, he usually focuses on Stereochemistry, concentrating on Structure–activity relationship and intersecting with Tubulin Modulators, Mechanism of action, IC50 and Paclitaxel.
The Internal medicine study combines topics in areas such as Endocrinology and Melanoma.
Wei Li has included themes like Calcitriol receptor and Receptor in his Biological activity study.
His most cited work include:
- HIF-1α pathway: role, regulation and intervention for cancer therapy (634 citations)
- An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site (387 citations)
- Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3. (281 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cancer research, Biochemistry, Cancer, Pharmacology and In vivo.
Wei Li has researched Cancer research in several fields, including Cancer cell, Metastasis, Cell growth and Survivin.
Biochemistry is a component of his Biological activity, Metabolism, Cholesterol side-chain cleavage enzyme, Vitamin and Cholecalciferol studies.
His work carried out in the field of Metabolism brings together such families of science as Stereochemistry and Hydroxylation.
His research investigates the link between Pharmacology and topics such as Tubulin that cross with problems in Paclitaxel, Colchicine and Cell cycle.
His research investigates the connection with In vivo and areas like In vitro which intersect with concerns in Cell culture.
He most often published in these fields:
- Cancer research (22.97%)
- Biochemistry (16.61%)
- Cancer (14.84%)
What were the highlights of his more recent work (between 2017-2021)?
- Cancer research (22.97%)
- Tubulin (11.31%)
- In vivo (14.49%)
In recent papers he was focusing on the following fields of study:
Wei Li mainly investigates Cancer research, Tubulin, In vivo, Cancer and Paclitaxel.
His Cancer research research incorporates themes from Apoptosis, Survivin, Triple-negative breast cancer and Metastasis.
His study on Tubulin also encompasses disciplines like
- Colchicine that connect with fields like Multiple drug resistance,
- Stereochemistry which connect with Protein structure.
His In vivo study integrates concerns from other disciplines, such as In vitro, Cell growth, Biomedical engineering and Biofilm.
His Cancer research includes elements of Western blot and NAPA.
His Melanoma course of study focuses on Cancer cell and Chemotherapy.
Between 2017 and 2021, his most popular works were:
- Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial (55 citations)
- A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance. (45 citations)
- Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy. (44 citations)
In his most recent research, the most cited papers focused on:
Cancer research, Tubulin, Colchicine, Cell cycle and Cancer are his primary areas of study.
His Cancer research research is multidisciplinary, incorporating perspectives in Cell culture, XIAP, Downregulation and upregulation, Cell division and Metastasis.
The study incorporates disciplines such as Melanoma, Biochemistry, Paclitaxel and In vivo in addition to Colchicine.
His Cell cycle research focuses on Drug and how it connects with Protein structure, Stereochemistry, Efflux and Moiety.
His Cancer study combines topics in areas such as Gastroenterology and NAPA.
His study in Microtubule is interdisciplinary in nature, drawing from both In vitro, Mechanism of action, Mitosis and Pharmacology.
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