Lawrence M. Pfeffer

Overview

Best Publications

• NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

  Osman Nidai Ozes;Lindsey D. Mayo;Jason A. Gustin;Susan R. Pfeffer

  2771
  Citations

• Biological Properties of Recombinant α-Interferons: 40th Anniversary of the Discovery of Interferons

  Lawrence M. Pfeffer;Charles A. Dinarello;Ronald B. Herberman;Bryan R. G. Williams

  668
  Citations

• STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor.

  Lawrence M. Pfeffer;Jerald E. Mullersman;Susan R. Pfeffer;Aruna Murti

  345
  Citations

• The Role of miR-21 in Cancer.

  Susan R. Pfeffer;Chuan He Yang;Lawrence M. Pfeffer

  343
  Citations

• Interferon α/β Promotes Cell Survival by Activating Nuclear Factor κB through Phosphatidylinositol 3-Kinase and Akt

  Chuan He Yang;Aruna Murti;Susan R. Pfeffer;Jong G. Kim

  259
  Citations

• Activation of chemokine and inflammatory cytokine response in hepatitis C virus–infected hepatocytes depends on toll‐like receptor 3 sensing of hepatitis C virus double‐stranded RNA intermediates

  Kui Li;Nan L. Li;Dahai Wei;Susan R. Pfeffer

  247
  Citations

• Induction of Jak/STAT Signaling by Activation of the Type 1 TNF Receptor

  DanQun Guo;James D. Dunbar;Chuan He Yang;Lawrence M. Pfeffer

  221
  Citations

• MicroRNA miR-21 Regulates the Metastatic Behavior of B16 Melanoma Cells

  Chuan He Yang;Junming Yue;Susan R. Pfeffer;Charles R. Handorf

  205
  Citations

• Interferon effects on microfilament organization, cellular fibronectin distribution, and cell motility in human fibroblasts.

  LM Pfeffer;E Wang;I Tamm

  204
  Citations

• IFN Induces miR-21 through a Signal Transducer and Activator of Transcription 3–Dependent Pathway as a Suppressive Negative Feedback on IFN-Induced Apoptosis

  Chuan He Yang;Junming Yue;Meiyun Fan;Lawrence M. Pfeffer

  199
  Citations

• IFNα/β promotes cell survival by activating NF-κB

  Chuan He Yang;Aruna Murti;Susan R. Pfeffer;Leela Basu

  192
  Citations

• Constitutive Activation of Signal Transducer and Activator of Transcription 3 (STAT3) and Nuclear Factor κB Signaling in Glioblastoma Cancer Stem Cells Regulates the Notch Pathway

  Jo Meagan Garner;Meiyun Fan;Chuan He Yang;Ziyun Du

  189
  Citations

• DNA Damage Induces NF-κB-dependent MicroRNA-21 Up-regulation and Promotes Breast Cancer Cell Invasion

  Jixiao Niu;Yuling Shi;Guangyun Tan;Guangyun Tan;Chuan He Yang

  180
  Citations

• MicroRNA-21 Promotes Glioblastoma Tumorigenesis by Down-regulating Insulin-like Growth Factor-binding Protein-3 (IGFBP3)

  Chuan He Yang;Junming Yue;Susan R. Pfeffer;Meiyun Fan

  179
  Citations

• Role of the JAK/STAT Pathway in the Regulation of Interleukin-8 Transcription by Oxidized Phospholipids in Vitro and in Atherosclerosis in Vivo

  Nima M. Gharavi;Jackelyn A. Alva;Kevin P. Mouillesseaux;Chi Lai

  177
  Citations

• The Role of Nuclear Factor κB in the Interferon Response

  Lawrence M. Pfeffer

  166
  Citations

• STAT3 complements defects in an interferon-resistant cell line: Evidence for an essential role for STAT3 in interferon signaling and biological activities

  Chuan-He Yang;Aruna Murti;Lawrence M. Pfeffer

  163
  Citations

• Direct Association of STAT3 with the IFNAR-1 Chain of the Human Type I Interferon Receptor

  Chuan-He Yang;Wei Shi;Leela Basu;Aruna Murti

  161
  Citations

• Chromenes: potential new chemotherapeutic agents for cancer

  Shivaputra A Patil;Renukadevi Patil;Lawrence M Pfeffer;Duane D Miller

  157
  Citations

• v-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine.

  Jianguo Song;L. M. Pfeffer;D. A. Foster

  153
  Citations