David B. Donner

Overview

Best Publications

• NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

  Osman Nidai Ozes;Lindsey D. Mayo;Jason A. Gustin;Susan R. Pfeffer

  2771
  Citations

• A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus.

  Lindsey D. Mayo;David B. Donner

  1706
  Citations

• Vascular Endothelial Cell Growth Factor Promotes Tyrosine Phosphorylation of Mediators of Signal Transduction That Contain SH2 Domains ASSOCIATION WITH ENDOTHELIAL CELL PROLIFERATION

  Danqun Guo;Qing Jia;Ho-Yeong Song;Robert S. Warren

  706
  Citations

• The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network.

  Lindsey D Mayo;David B Donner

  572
  Citations

• The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties.

  Sara J. Felts;Barbara A.L. Owen;PhuongMai Nguyen;Jane Trepel

  516
  Citations

• A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1

  Osman Nidai Ozes;Hakan Akca;Lindsey D. Mayo;Jason A. Gustin

  511
  Citations

• PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy.

  Lindsey D. Mayo;Jack E. Dixon;Donald L. Durden;Nickolas K. Tonks

  477
  Citations

• Induction of Vascular Endothelial Growth Factor by Insulin-like Growth Factor 1 in Colorectal Carcinoma

  Robert S. Warren;Hui Yuan;Mary R. Matli;Napoleone Ferrara

  390
  Citations

• Identification of a Protein with Homology to hsp90 That Binds the Type 1 Tumor Necrosis Factor Receptor

  Ho Yeong Song;James D. Dunbar;Yuan Xin Zhang;Danqun Guo

  387
  Citations

• Utilization of Distinct Signaling Pathways by Receptors for Vascular Endothelial Cell Growth Factor and Other Mitogens in the Induction of Endothelial Cell Proliferation

  Li-Wha Wu;Lindsey D. Mayo;James D. Dunbar;Kelly M. Kessler

  363
  Citations

• Cell Type-specific Expression of the IκB Kinases Determines the Significance of Phosphatidylinositol 3-Kinase/Akt Signaling to NF-κB Activation

  Jason A. Gustin;Osman N. Ozes;Hakan Akca;Roxana Pincheira

  272
  Citations

• Interferon α/β Promotes Cell Survival by Activating Nuclear Factor κB through Phosphatidylinositol 3-Kinase and Akt

  Chuan He Yang;Aruna Murti;Susan R. Pfeffer;Jong G. Kim

  259
  Citations

• Identification and characterization of receptors for tumor necrosis factor-α in the brain

  Keiko Kinouchi;George Brown;Gavril Pasternak;David B. Donner

  247
  Citations

• Induction of Jak/STAT Signaling by Activation of the Type 1 TNF Receptor

  DanQun Guo;James D. Dunbar;Chuan He Yang;Lawrence M. Pfeffer

  221
  Citations

• Phosphorylation of Human p53 at Serine 46 Determines Promoter Selection and whether Apoptosis Is Attenuated or Amplified

  Lindsey D. Mayo;Young Rok Seo;Mark W. Jackson;Martin L. Smith

  197
  Citations

• Expression of human papillomavirus type 16 E6 and E7 oncoproteins in primary foreskin keratinocytes is sufficient to alter the expression of angiogenic factors.

  Esra Toussaint-Smith;David B Donner;Ann Roman

  194
  Citations

• Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing.

  V Ankoma-Sey;M Matli;K B Chang;A Lalazar

  181
  Citations

• PTEN and Phosphatidylinositol 3′-Kinase Inhibitors Up-Regulate p53 and Block Tumor-induced Angiogenesis Evidence for an Effect on the Tumor and Endothelial Compartment

  Jing Dong Su;Lindsey D. Mayo;David B. Donner;Donald L. Durden

  174
  Citations

• Autocrine activation of PDGFRα promotes the progression of ovarian cancer

  Daniela Matei;Robert Emerson;Y. C. Lai;L. A. Baldridge

  168
  Citations

• The PTEN Tumor Suppressor Protein Inhibits Tumor Necrosis Factor-induced Nuclear Factor κB Activity *

  Jason A. Gustin;Tomohiko Maehama;Jack E. Dixon;David B. Donner

  163
  Citations