World's Best Scientists 2026 revealed!

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Medicine

D-Index
74
Citations
16194
World Ranking
19496
National Ranking
828

Overview

Benjamin K. Tsang is affiliated with the Ottawa Hospital Research Institute in Canada. Their research spans multiple domains within biochemistry, genetics, molecular biology, and medicine, emphasizing reproductive biology, immunology, and cancer research.

The scientist has contributed extensively to the following main fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader areas, specific subfields addressed in their work include:

  • Molecular Biology
  • Reproductive Medicine
  • Immunology
  • Cancer Research
  • Cell Biology

The research topics prominently featured in their publications cover:

  • Extracellular vesicles in disease
  • Caveolin-1 and cellular processes
  • MicroRNA in disease regulation
  • Ovarian function and disorders
  • Ovarian cancer diagnosis and treatment
  • Reproductive Biology and Fertility
  • Reproductive System and Pregnancy

Benjamin K. Tsang has published frequently in several venues, including:

  • Journal of Ovarian Research
  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Research Square (Research Square)

Notable recent papers authored or co-authored by Tsang are:

  • The role of pituitary gonadotropins and intraovarian regulators in follicle development: A mini-review (2021, Reproductive Medicine and Biology)
  • Plasma Gelsolin Inhibits CD8+ T-cell Function and Regulates Glutathione Production to Confer Chemoresistance in Ovarian Cancer (2020, Cancer Research)
  • Ovarian mitochondrial dynamics and cell fate regulation in an androgen-induced rat model of polycystic ovarian syndrome (2020, Scientific Reports)
  • Granulosa cell-derived miR-379-5p regulates macrophage polarization in polycystic ovarian syndrome (2023, Frontiers in Immunology)
  • Prognostic impact of Dynamin related protein 1 (Drp1) in epithelial ovarian cancer (2020, BMC Cancer)

The scientist has collaborated repeatedly with several co-authors, including:

  • Meshach Asare-Werehene
  • Dylan Burger
  • Reza Salehi
  • Eurídice Carmona
  • Anne-Marie Mes-Masson

Benjamin K. Tsang has also contributed to book literature, including a publication under Frontiers Media titled The Function of Secretory Factors in Immune Disorders (2023).

Best Publications

  • Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

    Han C. Dan;Mei Sun;Satoshi Kaneko;Richard I. Feldman

  • A new, nongenomic estrogen action: the rapid release of intracellular calcium.

    Paul Morley;James F. Whitfield;Barbara C. Vanderhyden;Benjamin K. Tsang

  • Down-Regulation of X-linked Inhibitor of Apoptosis Protein Induces Apoptosis in Chemoresistant Human Ovarian Cancer Cells

    Hiromasa Sasaki;YingLun Sheng;Fumikazu Kotsuji;Benjamin K. Tsang

  • XIAP Regulates Akt Activity and Caspase-3-dependent Cleavage during Cisplatin-induced Apoptosis in Human Ovarian Epithelial Cancer Cells

    Eric Asselin;Gordon B. Mills;Benjamin K. Tsang

  • The regulation of cell proliferation by calcium and cyclic AMP.

    J. F. Whitfield;A. L. Boynton;J. P. Macmanus;M. Sikorska

  • Akt-Mediated Cisplatin Resistance in Ovarian Cancer: Modulation of p53 Action on Caspase-Dependent Mitochondrial Death Pathway

    Xiaokui Yang;Michael Fraser;Ute M. Moll;Ajoy Basak

  • The roles of calcium and cyclic AMP in cell proliferation.

    J. F. Whitfield;A. L. Boynton;J. P. MacManus;R. H. Rixon

  • Human Ovarian Cancer and Cisplatin Resistance: Possible Role of Inhibitor of Apoptosis Proteins1

    Julang Li;Qiang Feng;Jong-Min Kim;Danielle Schneiderman

  • Oocyte-granulosa-theca cell interactions during preantral follicular development

    Makoto Orisaka;Kimihisa Tajima;Benjamin K Tsang;Fumikazu Kotsuji

  • Caspase-3 in the rat ovary: localization and possible role in follicular atresia and luteal regression.

    David L. Boone;Benjamin K. Tsang

  • p53 Is a Determinant of X-Linked Inhibitor of Apoptosis Protein/Akt-Mediated Chemoresistance in Human Ovarian Cancer Cells

    Michael Fraser;Brendan M. Leung;Xiaojuan Yan;Han C. Dan

  • Growth Differentiation Factor 9 Is Antiapoptotic during Follicular Development from Preantral to Early Antral Stage

    Makoto Orisaka;Sanae Orisaka;Sanae Orisaka;Jin-Yi Jiang;Jesse Craig

  • Regulation of cell death and cell survival gene expression during ovarian follicular development and atresia.

    Jin-Yi Jiang;Carmen K M Cheung;Yifang Wang;Benjamin K Tsang

  • Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway.

    Jin Q Cheng;Xiuxian Jiang;Xiuxian Jiang;Michael Fraser;Michael Fraser;Ming Li;Ming Li

  • Gonadotropin and intra-ovarian signals regulating follicle development and atresia: the delicate balance between life and death.

    Jesse Craig;Makoto Orisaka;Hongmei Wang;Sanae Orisaka

  • Chemoresistance in human ovarian cancer: the role of apoptotic regulators

    Michael Fraser;Brendan Leung;Arezu Jahani-Asl;Xiaojuan Yan

  • Akt promotes cisplatin resistance in human ovarian cancer cells through inhibition of p53 phosphorylation and nuclear function.

    Michael Fraser;Tao Bai;Tao Bai;Benjamin K. Tsang

  • Involvement of the Fas/Fas ligand system in p53-mediated granulosa cell apoptosis during follicular development and atresia

    Jong-Min Kim;Yong-Dal Yoon;Benjamin K. Tsang

  • Interrelationships Between Follicular Fluid Steroid Levels, GonadotropiC Stimuli, and Oocyte Maturation During Preovulatory Development of Porcine Follicles

    L. Ainsworth;B. K. Tsang;B. R. Downey;G. J. Marcus

  • 17 beta-Estradiol biosynthesis in cultured granulosa and thecal cells of human ovarian follicles: stimulation by follicle-stimulating hormone.

    Y. S. Moon;B. K. Tsang;C. Simpson;D. T. Armstrong

Frequent Co-Authors

James F. Whitfield
James F. Whitfield National Academies of Sciences, Engineering, and Medicine
Yong Sang Song
Yong Sang Song Seoul National University
Robert G. Korneluk
Robert G. Korneluk University of Ottawa
Alex MacKenzie
Alex MacKenzie Children's Hospital of Eastern Ontario
David T. Armstrong
David T. Armstrong National Institute of Environmental Health Sciences
Hyong Joo Lee
Hyong Joo Lee Seoul National University
Barbara C. Vanderhyden
Barbara C. Vanderhyden University of Ottawa
David T. Curiel
David T. Curiel Washington University in St. Louis
Stefano Palomba
Stefano Palomba Magna Graecia University
John P. MacManus
John P. MacManus National Academies of Sciences, Engineering, and Medicine

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