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Hextan Y.S. Ngan

Hextan Y.S. Ngan

D-Index & Metrics

Medicine

D-Index
79
Citations
22063
World Ranking
17598
National Ranking
200

Overview

Hextan Y.S. Ngan is affiliated with the University of Hong Kong in China and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research mainly spans cancer research, molecular biology, surgery, obstetrics and gynecology, and reproductive medicine.

Their scientific output includes studies focusing on ovarian cancer diagnosis and treatment, endometrial and cervical cancer treatments, cervical cancer and HPV research, cancer-related lipid metabolism, hypoxia, and ferroptosis, as well as investigations into gestational trophoblastic disease.

Recent notable publications include:

  • Diagnosis and management of gestational trophoblastic disease: 2021 update, 2021, International Journal of Gynecology & Obstetrics
  • The Impact of the Tumor Microenvironment on Macrophage Polarization in Cancer Metastatic Progression, 2021, International Journal of Molecular Sciences
  • SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells, 2022, Theranostics
  • Molecular Biomarkers for the Early Detection of Ovarian Cancer, 2022, International Journal of Molecular Sciences
  • MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis, 2020, Pharmacological Research

Frequent coauthors in their body of work include Karen K. L. Chan, Siew-Fei Ngu, Any Cheung, and David W. Chan, reflecting ongoing collaborative research efforts.

Key publication venues for their research are:

  • Cancers
  • Cancer Research
  • International Journal of Molecular Sciences
  • Best Practice & Research Clinical Obstetrics & Gynaecology
  • Journal of Clinical Oncology

Best Publications

  • FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology.

    Benedet Jl;Bender H;Jones H rd;Ngan Hy

  • Revised FIGO staging for carcinoma of the cervix uteri

    Neerja Bhatla;Jonathan S. Berek;Mauricio Cuello Fredes;Lynette A. Denny

  • Trabectedin Plus Pegylated Liposomal Doxorubicin in Recurrent Ovarian Cancer

    Bradley J. Monk;Thomas J. Herzog;Stanley B. Kaye;Carolyn N. Krasner

  • Effect of Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy on Disease-Free Survival Among Women With Stage I Endometrial Cancer: A Randomized Clinical Trial.

    Monika Janda;Val Gebski;Lucy C. Davies;Peta Forder

  • Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): a randomised trial

    Monika Janda;Val Gebski;Alison Brand;Russel Hogg

  • Update on the diagnosis and management of gestational trophoblastic disease

    Hextan Y.S. Ngan;Michael J. Seckl;Ross S. Berkowitz;Yang Xiang

  • High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas.

    Vincent W. S. Liu;Hong Hui Shi;Annie N. Y. Cheung;Pui Man Chiu

  • Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation

    Xiaoyun Liao;Michelle K.Y. Siu;Christy W.H. Au;Esther S.Y. Wong

  • Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells

    David W. Chan;Vincent W.S. Liu;George S.W. Tsao;Kwok Ming Yao

  • Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data.

    Hui-Juan Yang;Vincent W S Liu;Yue Wang;Percy C K Tsang

  • p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

    Michelle K. Y. Siu;Hoi Yan Chan;Daniel S. H. Kong;Esther S. Y. Wong

  • Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface.

    Maggie K.S. Tang;Patrick Y.K. Yue;Philip P. Ip;Rui Lan Huang

  • Over-expression of FOXM1 transcription factor is associated with cervical cancer progression and pathogenesis†

    D. W. Chan;S. Y. M. Yu;P. M. Chiu;K. M. Yao

  • Epigenetic Factors Controlling the BRCA1 and BRCA2 Genes in Sporadic Ovarian Cancer

    Kelvin Y. K. Chan;Hilmi Ozçelik;Annie N. Y. Cheung;Hextan Y. S. Ngan

  • Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection

    Vera S.F. Chan;Kelvin Y.K. Chan;Yongxiong Chen;Leo L.M. Poon

  • TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies

    Stefanie J. Klug;Meike Ressing;Jochem Koenig;Martin C. Abba

  • The Impact of the Tumor Microenvironment on Macrophage Polarization in Cancer Metastatic Progression

    Huogang Wang;Mingo M. H. Yung;Hextan Y. S. Ngan;Karen K. L. Chan

  • Diagnosis and management of gestational trophoblastic disease: 2021 update.

    Hextan Y. S. Ngan;Michael J. Seckl;Ross S. Berkowitz;Yang Xiang

  • The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: A quantitative study using laser-captured microdissected tissues

    Yue Wang;Vincent W.S. Liu;Wei-Cheng Xue;Percy C.K. Tsang

  • The use of music to reduce anxiety for patients undergoing colposcopy: A randomized trial

    Y.M Chan;Peter W.H Lee;T.Y Ng;Hextan Y.S Ngan

Frequent Co-Authors

Sai Wah Tsao
Sai Wah Tsao University of Hong Kong
Yee Leung
Yee Leung Chinese University of Hong Kong
Val Gebski
Val Gebski University of Sydney
Benjamin K. Tsang
Benjamin K. Tsang Ottawa Hospital Research Institute
Russell Hogg
Russell Hogg Queensland University of Technology
Phillip Nagley
Phillip Nagley Monash University
Hilmi Ozcelik
Hilmi Ozcelik University of Toronto
Suzanne M. Garland
Suzanne M. Garland University of Melbourne
Xin Lu
Xin Lu University of Oxford
Irene L. Andrulis
Irene L. Andrulis University of Toronto

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