World's Best Scientists 2026 revealed!
Barbara C. Vanderhyden

Barbara C. Vanderhyden

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
14224
World Ranking
9206
National Ranking
316

Overview

Barbara C. Vanderhyden is affiliated with the University of Ottawa in Canada. Their research spans several interconnected fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their work frequently touches on subfields such as Immunology, Molecular Biology, Oncology, Cancer Research, and Reproductive Medicine.

Vanderhyden's research encompasses topics related to immune cell function and interaction, cancer cells and metastasis, ovarian cancer diagnosis and treatment, immune cells in cancer, reproductive system and pregnancy, reproductive biology and fertility, as well as cancer immunotherapy and biomarkers.

Among recent publications, notable papers include:

  • Context specificity of the EMT transcriptional response, 2020, Nature Communications
  • Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells, 2021, Autophagy
  • Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage, 2021, Nature Communications
  • Metformin prevents age-associated ovarian fibrosis by modulating the immune landscape in female mice, 2022, Science Advances
  • Transcriptional census of epithelial-mesenchymal plasticity in cancer, 2022, Science Advances

Frequent co-authors of Vanderhyden include:

  • David P. Cook
  • Galaxia M. Rodriguez
  • Elizabeth A. Macdonald
  • Edward Yakubovich
  • Kristianne J.C. Galpin

The scientist has published multiple papers in prominent venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Frontiers in Immunology
  • Cancers
  • Nature Communications

Best Publications

  • Mutation of FOXL2 in Granulosa-Cell Tumors of the Ovary

    Sohrab P Shah;Martin Köbel;Janine Senz;Ryan D Morin

  • A new, nongenomic estrogen action: the rapid release of intracellular calcium.

    Paul Morley;James F. Whitfield;Barbara C. Vanderhyden;Benjamin K. Tsang

  • FSH-induced expansion of the mouse cumulus oophorus in vitro is dependent upon a specific factor(s) secreted by the oocyte.

    Roberto Buccione;Barbara C. Vanderhyden;Philip J. Caron;John J. Eppig

  • Developmental pattern of the secretion of cumulus expansion-enabling factor by mouse oocytes and the role of oocytes in promoting granulosa cell differentiation.

    Barbara C. Vanderhyden;Philip J. Caron;Roberto Buccione;John J. Eppig

  • Female Mice Chimeric for Expression of the Simian Virus 40 TAg under Control of the MISIIR Promoter Develop Epithelial Ovarian Cancer

    Denise C. Connolly;Rudi Bao;Alexander Yu Nikitin;Kasie C. Stephens

  • Bidirectional communication between oocytes and follicle cells: ensuring oocyte developmental competence.

    Gerald M. KidderG.M. Kidder;Barbara C. VanderhydenB.C. Vanderhyden

  • Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

    Ninan Abraham;David F. Stojdl;Peter I. Duncan;Nathalie Méthot

  • The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers

    Kelley A Parato;Caroline J Breitbach;Fabrice Le Boeuf;Jiahu Wang

  • Mouse oocytes promote proliferation of granulosa cells from preantral and antral follicles in vitro.

    Barbara C Vanderhyden;Evelyn E Telfer;John J Eppig

  • Human Ovarian Cancer and Cisplatin Resistance: Possible Role of Inhibitor of Apoptosis Proteins1

    Julang Li;Qiang Feng;Jong-Min Kim;Danielle Schneiderman

  • Oocyte-granulosa cell interactions during mouse follicular development: regulation of kit ligand expression and its role in oocyte growth.

    Fiona H Thomas;Barbara C Vanderhyden

  • Risk factors for ovarian cancer: an overview with emphasis on hormonal factors.

    Fariba Salehi;Lesley Dunfield;Karen P. Phillips;Daniel Krewski

  • Mouse oocytes regulate granulosa cell steroidogenesis

    B C Vanderhyden;J N Cohen;P Morley

  • Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis.

    Thi Lien-Anh Nguyên;Hesham Abdelbary;Meztli Arguello;Caroline Breitbach

  • Focal and Segmental Glomerulosclerosis in Mice with Podocyte-Specific Expression of Mutant α-Actinin-4

    Jean-Louis Michaud;Lyne I. Lemieux;Manon Dubé;Barbara C. Vanderhyden

  • An Immunohistochemical Algorithm for Ovarian Carcinoma Typing.

    Martin Köbel;Kurosh Rahimi;Peter F. Rambau;Christopher Naugler;Christopher Naugler

  • Context specificity of the EMT transcriptional response

    David P. Cook;David P. Cook;Barbara C. Vanderhyden;Barbara C. Vanderhyden

  • Follicle-Stimulating Hormone Regulates Oocyte Growth by Modulation of Expression of Oocyte and Granulosa Cell Factors

    Fiona H. Thomas;Jean-François Ethier;Shunichi Shimasaki;Barbara C. Vanderhyden

  • Animal models of ovarian cancer.

    Barbara C Vanderhyden;Tanya J Shaw;Jean-François Ethier

  • Differential Regulation of Progesterone and Estradiol Production by Mouse Cumulus and Mural Granulosa Cells by a Factor(s) Secreted by the Oocyte

    Barbara C. Vanderhyden;Angela M. Tonary

Frequent Co-Authors

John C. Bell
John C. Bell University of Ottawa
David G. Huntsman
David G. Huntsman University of British Columbia
Benjamin K. Tsang
Benjamin K. Tsang Ottawa Hospital Research Institute
Martin Köbel
Martin Köbel University of Calgary
Diane Provencher
Diane Provencher University of Montreal
Ralf Hass
Ralf Hass Hannover Medical School
John J. Eppig
John J. Eppig Jackson Laboratory
Mary-Ellen Harper
Mary-Ellen Harper University of Ottawa
Robert W. Boyd
Robert W. Boyd University of Ottawa
Patricia N. Tonin
Patricia N. Tonin McGill University

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