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Medicine

D-Index
82
Citations
21744
World Ranking
16260
National Ranking
681

Overview

Martin Köbel is affiliated with the University of Calgary in Canada and contributes extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research predominantly focuses on reproductive medicine, obstetrics and gynecology, and molecular biology within the oncology and cancer research spheres.

The main research topics explored by Köbel include ovarian cancer diagnosis and treatment, endometrial and cervical cancer treatments, chromatin remodeling and cancer, cancer-related molecular mechanisms research, cancer mechanisms and therapy, uterine myomas and treatments, as well as endometriosis research and treatment.

They have published numerous scientific articles, with some recent notable papers being:

  • "Prognostic gene expression signature for high-grade serous ovarian cancer" (2020), published in Annals of Oncology
  • "Evaluation of treatment effects in patients with endometrial cancer and POLE mutations: An individual patient data meta-analysis" (2021), published in Cancer
  • "Genomic analysis of low-grade serous ovarian carcinoma to identify key drivers and therapeutic vulnerabilities" (2020), published in The Journal of Pathology
  • "The Evolution of Ovarian Carcinoma Subclassification" (2022), published in Cancers
  • "Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes" (2022), published in Clinical Cancer Research

Köbel frequently collaborates with a group of researchers, several of whom they have co-authored a substantial number of papers with. Key collaborators include:

  • David G. Huntsman
  • Michael S. Anglesio
  • Aline Talhouk
  • Susan J. Ramus
  • Anna DeFazio

Their work is published in a range of scientific journals, with the most frequent venues being:

  • Gynecologic Oncology
  • International Journal of Gynecological Pathology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Histopathology
  • The Journal of Pathology

Best Publications

  • Ovarian Carcinoma Subtypes Are Different Diseases: Implications for Biomarker Studies

    Martin Köbel;Martin Köbel;Steve E Kalloger;Niki Boyd;Steven McKinney

  • Mutation of FOXL2 in Granulosa-Cell Tumors of the Ovary

    Sohrab P Shah;Martin Köbel;Janine Senz;Ryan D Morin

  • Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

    Roel G.W. Verhaak;Pablo Tamayo;Ji Yeon Yang;Diana Hubbard

  • Systematic Analysis of Immune Infiltrates in High-Grade Serous Ovarian Cancer Reveals CD20, FoxP3 and TIA-1 as Positive Prognostic Factors

    Katy Milne;Martin Köbel;Steven E. Kalloger;Rebecca O. Barnes

  • Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

    Weiva Sieh;Martin Köbel;Teri A Longacre;David D Bowtell;David D Bowtell

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Invasive Epithelial Ovarian Cancer Survival by Histotype and Disease Stage.

    Lauren C Peres;Kara L Cushing-Haugen;Martin Köbel;Holly R Harris

  • Differences in tumor type in low-stage versus high-stage ovarian carcinomas.

    Martin Köbel;Steve E. Kalloger;David G. Huntsman;Jennifer L. Santos

  • Interpretation of P53 Immunohistochemistry in Endometrial Carcinomas: Toward Increased Reproducibility.

    Martin Köbel;Brigitte M. Ronnett;Naveena Singh;Robert A. Soslow

  • Optimized p53 immunohistochemistry is an accurate predictor of TP53 mutation in ovarian carcinoma

    Martin Köbel;Anna Maria Piskorz;Sandra Lee;Shuhong Lui

  • Expression of Cyclooxygenase 2 in Human Malignant Melanoma

    Carsten Denkert;Martin Köbel;Stefan Berger;Antje Siegert

  • Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma.

    Carsten Denkert;Klaus-Jürgen Winzer;Berit-Maria Müller;Wilko Weichert

  • Dose-Response Association of CD8(+) Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

    Ellen L. Goode;Matthew S. Block;Kimberly R. Kalli;Robert A. Vierkant

  • Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell Symposium, June 24th, 2010.

    Michael S Anglesio;Mark S Carey;Martin Köbel;Helen Mackay

  • Expression of Cyclooxygenase 2 Is an Independent Prognostic Factor in Human Ovarian Carcinoma

    Carsten Denkert;Martin Köbel;Sören Pest;Ines Koch

  • Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma

    C. Blake Gilks;Diana N. Ionescu;Steve E. Kalloger;Martin Köbel;Martin Köbel

  • The fallopian tube: primary site of most pelvic high-grade serous carcinomas.

    Shannon Salvador;Blake Gilks;Martin Köbel;David G Huntsman

  • A limited panel of immunomarkers can reliably distinguish between clear cell and high-grade serous carcinoma of the ovary.

    Martin Köbel;Steve E. Kalloger;Jon Carrick;David Huntsman

  • Polo-like kinase isoform expression is a prognostic factor in ovarian carcinoma

    W Weichert;C Denkert;M Schmidt;V Gekeler

  • p53 immunohistochemistry is an accurate surrogate for TP53 mutational analysis in endometrial carcinoma biopsies

    Naveena Singh;Anna M Piskorz;Tjalling Bosse;Mercedes Jimenez-Linan

Frequent Co-Authors

David G. Huntsman
David G. Huntsman University of British Columbia
C. Blake Gilks
C. Blake Gilks University of British Columbia
Susan J. Ramus
Susan J. Ramus University of New South Wales
David D.L. Bowtell
David D.L. Bowtell Peter MacCallum Cancer Centre
Ellen L. Goode
Ellen L. Goode Mayo Clinic
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
James D. Brenton
James D. Brenton University of Cambridge
Ian G. Campbell
Ian G. Campbell Peter MacCallum Cancer Centre
Beth Y. Karlan
Beth Y. Karlan University of California, Los Angeles

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