World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
48
Citations
11386
World Ranking
4401
National Ranking
1997

Reiko Horai publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Reiko Horai sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 140 publications — 13th percentile

13% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Reiko Horai D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Reiko Horai sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 48 D-Index — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Reiko Horai is affiliated with the National Eye Institute in the United States. Their research primarily focuses on immunology and ophthalmology, intersecting with medicine and microbiology. Horai's work addresses mechanisms of ocular diseases and autoimmune disorders from a cellular and molecular perspective.

Their publications cover various topics including ocular diseases and Behçet's syndrome, psoriasis treatment and pathogenesis, cytomegalovirus and herpesvirus research, immunodeficiency and autoimmune disorders, systemic lupus erythematosus research, interferon and immune responses, and T-cell and B-cell immunology.

Horai has contributed notable papers such as:

  • The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24 (2020, Immunity)
  • T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis (2020, Nature Communications)
  • Microbiota as Drivers and as Therapeutic Targets in Ocular and Tissue Specific Autoimmunity (2021, Frontiers in Cell and Developmental Biology)
  • A novel role for lipoxin A4 in driving a lymph node-eye axis that controls autoimmunity to the neuroretina (2020, eLife)
  • Autoimmunity to neuroretina in the concurrent absence of IFN-γ and IL-17A is mediated by a GM-CSF-driven eosinophilic inflammation (2020, Journal of Autoimmunity)

Their frequent coauthors include:

  • Rachel R Caspi
  • Mary J. Mattapallil
  • Yingyos Jittayasothorn
  • Vijayaraj Nagarajan
  • So Jin Bing

Horai's research has appeared repeatedly in venues such as The Journal of Immunology, bioRxiv (Cold Spring Harbor Laboratory), Immunity, Nature Communications, and Frontiers in Cell and Developmental Biology. The Journal of Immunology and bioRxiv represent the most common platforms for their work.

The main fields of study associated with Horai's publications include Medicine and Immunology and Microbiology. Within these, their work often focuses on subfields like Immunology, Ophthalmology, Epidemiology, Molecular Biology, and Rheumatology.

Best Publications

  • Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist–Deficient Mice

    Reiko Horai;Shinobu Saijo;Hidetoshi Tanioka;Susumu Nakae

  • Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion

    Reiko Horai;Masahide Asano;Katsuko Sudo;Hirotaka Kanuka

  • IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

    Susumu Nakae;Shinobu Saijo;Reiko Horai;Katsuko Sudo

  • Role of IL-1alpha and IL-1beta in ischemic brain damage.

    H. Boutin;R. A. LeFeuvre;R. Horai;M. Asano

  • Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand

    Keiko Miwa;Masahide Asano;Reiko Horai;Yoichiro Iwakura

  • Cutting Edge: NKT Cells Constitutively Express IL-23 Receptor and RORγt and Rapidly Produce IL-17 upon Receptor Ligation in an IL-6-Independent Fashion

    Aleksandra V. Rachitskaya;Anna M. Hansen;Reiko Horai;Zhuqing Li

  • Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site

    Reiko Horai;Carlos R. Zárate-Bladés;Patricia Dillenburg-Pilla;Jun Chen;Jun Chen

  • IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions

    Taizo Matsuki;Reiko Horai;Katsuko Sudo;Yoichiro Iwakura

  • Protective Role of Interleukin-1 in Mycobacterial Infection in IL-1 α/β Double-Knockout Mice

    Hiroyuki Yamada;Satoru Mizumo;Reiko Horai;Yoichiro Iwakura

  • Cytokines in autoimmune uveitis.

    Reiko Horai;Rachel R. Caspi

  • Altered Development of CD8+ T Cell Lineages in Mice Deficient for the Tec Kinases Itk and Rlk

    Christine Broussard;Christine Fleischacker;Reiko Horai;Madeva Chetana

  • Interleukin‐1β, but not interleukin‐1α, is required for T‐cell‐dependent antibody production

    Susumu Nakae;Masahide Asano;Masahide Asano;Reiko Horai;Yoichiro Iwakura

  • SAP regulates T cell–mediated help for humoral immunity by a mechanism distinct from cytokine regulation

    Jennifer L. Cannons;Li J. Yu;Dragana Jankovic;Shane Crotty

  • IL‐1 is required for allergen‐specific Th2 cell activation and the development of airway hypersensitivity response

    Susumu Nakae;Yutaka Komiyama;Hiroshi Yokoyama;Aya Nambu

  • Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis

    Taizo Matsuki;Susumu Nakae;Katsuko Sudo;Reiko Horai

  • Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk.

    Julie A. Readinger;Kristen L. Mueller;Ana M. Venegas;Reiko Horai

  • TNF-α is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist–deficient mice

    Reiko Horai;Akiko Nakajima;Katsuyoshi Habiro;Motoko Kotani

  • IL-1 Enhances T Cell-Dependent Antibody Production Through Induction of CD40 Ligand and OX40 on T Cells

    Susumu Nakae;Masahide Asano;Reiko Horai;Nobuo Sakaguchi

  • NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity.

    Takanobu Nakazawa;Shoji Komai;Ayako M Watabe;Yuji Kiyama

  • The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24.

    Wai Po Chong;Wai Po Chong;Mary J. Mattapallil;Kumarkrishna Raychaudhuri;So Jin Bing

  • Deficiency of Interleukin-1 Receptor Antagonist Promotes Neointimal Formation After Injury

    Kikuo Isoda;Masaru Shiigai;Norio Ishigami;Taizo Matsuki

  • Requirements for selection of conventional and innate T lymphocyte lineages.

    Reiko Horai;Kristen L. Mueller;Robin A. Handon;Jennifer L. Cannons

Frequent Co-Authors

Rachel R. Caspi
Rachel R. Caspi National Institutes of Health
Phyllis B. Silver
Phyllis B. Silver National Institutes of Health
Chi-Chao Chan
Chi-Chao Chan National Institutes of Health
Pamela L. Schwartzberg
Pamela L. Schwartzberg National Institutes of Health
Jun Chen
Jun Chen Sun Yat-sen University
Stacie M. Anderson
Stacie M. Anderson National Institutes of Health
Martha Kirby
Martha Kirby National Institutes of Health
Kenya Honda
Kenya Honda Keio University
Joseph F. Petrosino
Joseph F. Petrosino Baylor College of Medicine
Nadim J. Ajami
Nadim J. Ajami The University of Texas MD Anderson Cancer Center

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