Phyllis B. Silver mostly deals with Immunology, Autoimmunity, Antigen, Interferon gamma and Retinal. The study of Immunology is intertwined with the study of Interleukin 12 in a number of ways. Her work deals with themes such as Innate immune system and Peptide sequence, which intersect with Autoimmunity.
Her Antigen study integrates concerns from other disciplines, such as T cell, Uveitis and Immunity. Her research is interdisciplinary, bridging the disciplines of Interleukin 17 and Interferon gamma. Her studies in Cytokine integrate themes in fields like Delayed hypersensitivity and Adoptive cell transfer.
Phyllis B. Silver spends much of her time researching Immunology, Autoimmunity, Antigen, Autoimmune uveitis and Uveitis. Her study in Immunology focuses on Autoimmune disease, Effector, Cytokine, Interleukin 17 and Immune system. Phyllis B. Silver has included themes like Lymphocyte proliferation, Adoptive cell transfer and Pertussis toxin in her Autoimmune disease study.
She interconnects Inflammation and Priming in the investigation of issues within Cytokine. Her research in Autoimmunity intersects with topics in Pathogenesis, Retinal, Immune tolerance, Endogeny and T-cell receptor. Phyllis B. Silver focuses mostly in the field of Antigen, narrowing it down to topics relating to T cell and, in certain cases, Immunization.
Her primary areas of study are Immunology, Autoimmunity, Uveitis, Autoimmune uveitis and Cytokine. She regularly links together related areas like Transgene in her Immunology studies. Her Autoimmunity study combines topics from a wide range of disciplines, such as Multiple sclerosis and Endogeny.
The Uveitis study combines topics in areas such as Innate immune system, Mediator, Crosstalk and C-type lectin. Her Cytokine research includes elements of Interleukin 12, Janus kinase 3, Interleukin 21, Neuroinflammation and Innate lymphoid cell. Her T cell research focuses on Interleukin 17 and how it relates to Candida albicans.
Phyllis B. Silver mainly investigates Immunology, Uveitis, Antigen, T cell and Signal transduction. Much of her study explores Immunology relationship to In vivo. Her Antigen research is multidisciplinary, incorporating perspectives in Adjuvant, Pertussis toxin, Transcription factor and Haplotype.
Her biological study spans a wide range of topics, including Retinal, Interleukin 17, Transgene and Immunization. The various areas that Phyllis B. Silver examines in her Signal transduction study include Innate immune system, Autoimmune disease and C-type lectin. Her Autoimmunity research integrates issues from Receptor, Endogeny and Immune tolerance.
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Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category.
Dror Luger;Phyllis B Silver;Jun Tang;Daniel J. Cua.
Journal of Experimental Medicine (2008)
Calcitriol Suppresses Antiretinal Autoimmunity through Inhibitory Effects on the Th17 Effector Response
Jun Tang;Ru Zhou;Dror Luger;Wei Zhu.
Journal of Immunology (2009)
Interleukin 12 Protects from a T Helper Type 1–mediated Autoimmune Disease, Experimental Autoimmune Uveitis, through a Mechanism Involving Interferon γ, Nitric Oxide, and Apoptosis
Teresa K. Tarrant;Phyllis B. Silver;Jennifer L. Wahlsten;Luiz Vicente Rizzo.
Journal of Experimental Medicine (1999)
Endogenous systemic IFN-gamma has a protective role against ocular autoimmunity in mice.
RR Caspi;CC Chan;BG Grubbs;PB Silver.
Journal of Immunology (1994)
Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site
Reiko Horai;Carlos R. Zárate-Bladés;Patricia Dillenburg-Pilla;Jun Chen;Jun Chen.
Immunity (2015)
Essential Role of the MyD88 Pathway, but Nonessential Roles of TLRs 2, 4, and 9, in the Adjuvant Effect Promoting Th1-Mediated Autoimmunity
Shao Bo Su;Phyllis B. Silver;Rafael S. Grajewski;Rajeev K. Agarwal.
Journal of Immunology (2005)
Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response.
R R Caspi;P B Silver;C C Chan;B Sun.
Journal of Immunology (1996)
Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype.
Dody Avichezer;Phyllis B. Silver;Chi-Chao Chan;Barbara Wiggert.
Investigative Ophthalmology & Visual Science (2000)
Rodent models of experimental autoimmune uveitis.
Rajeev K Agarwal;Phyllis B Silver;Rachel R Caspi.
Methods of Molecular Biology (2012)
Autoimmune Uveitis Elicited with Antigen-Pulsed Dendritic Cells Has a Distinct Clinical Signature and Is Driven by Unique Effector Mechanisms: Initial Encounter with Autoantigen Defines Disease Phenotype
Jun Tang;Wei Zhu;Phyllis B. Silver;Shao Bo Su.
Journal of Immunology (2007)
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