2026 Chi-Chao Chan: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	115	398	365	246	222	732	46045
Medicine	115	4563	4278	2478	2293	750	46869

Overview

Chi-Chao Chan is affiliated with the National Institutes of Health in the United States. Their research is primarily situated within the field of Medicine, with a significant focus on Ophthalmology, Immunology, Neurology, Molecular Biology, and Pathology and Forensic Medicine as subfields.

The scientist's work covers multiple main topics including:

Ocular Diseases and Behçet's Syndrome
Psoriasis: Treatment and Pathogenesis
Gut microbiota and health
Barrier Structure and Function Studies
CNS Lymphoma Diagnosis and Treatment
Mast cells and histamine
Ocular Oncology and Treatments

Recent publications by Chi-Chao Chan include:

"The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24" (2020), published in Immunity
"Identification of an intraocular microbiota" (2021), published in Cell Discovery
"Logistic Regression Classification of Primary Vitreoretinal Lymphoma versus Uveitis by Interleukin 6 and Interleukin 10 Levels" (2020), published in Ophthalmology
"Autoimmunity to neuroretina in the concurrent absence of IFN-γ and IL-17A is mediated by a GM-CSF-driven eosinophilic inflammation" (2020), published in Journal of Autoimmunity
"Multimodal Imaging Features of Bilateral Choroidal Ganglioneuroma" (2020), published in Journal of Ophthalmology

Chi-Chao Chan frequently collaborates with several coauthors, including Rachel R Caspi, Phyllis B. Silver, Mary J. Mattapallil, So Jin Bing, and Yingyos Jittayasothorn.

The scientist has also contributed to book publications, including one titled Novel Diagnostic and Therapeutic Strategies in Pediatric Vitreoretinal Disease (2023), published by Frontiers Media.

Key journals and venues for Chan's publications include:

Cell Discovery
Experimental Eye Research
The Journal of Immunology
Journal of American Association for Pediatric Ophthalmology and Strabismus
Immunity

Best Publications

Tumor-specific Th17-polarized cells eradicate large established melanoma

Pawel Muranski;Andrea Boni;Paul A. Antony;Lydie Cassard

1039
Citations
CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4 T helper cells and hindered by naturally occurring T regulatory cells.

Paul A. Antony;Ciriaco A. Piccirillo;Akgül Akpinarli;Steven E. Finkelstein

947
Citations
Seven new loci associated with age-related macular degeneration

Lars G. Fritsche;Lars G. Fritsche;Wei Chen;Wei Chen;Matthew Schu;Brian L. Yaspan

876
Citations
Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category.

Dror Luger;Phyllis B Silver;Jun Tang;Daniel J. Cua

850
Citations
Rapamycin slows aging in mice.

John E. Wilkinson;Lisa Burmeister;Susan V. Brooks;Chi Chao Chan

769
Citations
Standardizatlon of Vitreal inflammatory Activity in Intermediate and Posterior Uveitis

Robert B. Nussenblatt;Alan G. Palestine;Chi-Chao Chan;François Roberge

740
Citations
The Rd8 Mutation of the Crb1 Gene Is Present in Vendor Lines of C57BL/6N Mice and Embryonic Stem Cells, and Confounds Ocular Induced Mutant Phenotypes

Mary J. Mattapallil;Eric F. Wawrousek;Chi-Chao Chan;Hui Zhao

732
Citations
Molecular pathology of age-related macular degeneration

Xiaoyan Ding;Mrinali Patel;Mrinali Patel;Chi-Chao Chan

723
Citations
Central retinal vein occlusion: a prospective histopathologic study of 29 eyes in 28 cases.

W R Green;C C Chan;G M Hutchins;J M Terry

712
Citations
Vaccination with a recombinant vaccinia virus encoding a “self” antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4+ T lymphocytes

Willem W. Overwijk;David S. Lee;Deborah R. Surman;Kari R. Irvine

547
Citations
A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens.

R. R. Caspi;F. G. Roberge;Chi-Chao Chan;B. Wiggert

546
Citations
Primary Vitreoretinal Lymphoma: A Report from an International Primary Central Nervous System Lymphoma Collaborative Group Symposium

Chi Chao Chan;James L. Rubenstein;Sarah E. Coupland;Janet L. Davis

516
Citations
Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature

Pawel Muranski;Zachary A. Borman;Sid P. Kerkar;Christopher A. Klebanoff

516
Citations
Conjunctival T-Cell Subpopulations in Sjogren's and Non-Sjogren's Patients with Dry Eye

Michael E. Stern;Jianping Gao;Tammy A. Schwalb;Mylinh Ngo

442
Citations
Calcitriol Suppresses Antiretinal Autoimmunity through Inhibitory Effects on the Th17 Effector Response

Jun Tang;Ru Zhou;Dror Luger;Wei Zhu

437
Citations
Serum inflammatory markers in diabetic retinopathy.

Annal D. Meleth;Elvira Agrón;Chi-Chao Chan;George F. Reed

421
Citations
Ophthalmic Involvement in Acquired Immunodeficiency Syndrome

Alan G. Palestine;Merlyn M. Rodrigues;Abe M. Macher;Chi-Chao Chan

409
Citations
Cyclosporin a Therapy in the Treatment of Intraocular Inflammatory Disease Resistant to Systemic Corticosteroids and Cytotoxic Agents

Robert B. Nussenblatt;Alan G. Palestine;Chi-Chao Chan

403
Citations
Side Effects of Systemic Cyclosporine in Patients Not Undergoing Transplantation

A.G. Palestine;R.B. Nussenblatt;C.-C. Chan

398
Citations
Intraocular lymphoma. Clinical and histopathologic diagnosis.

S. M. Whitcup;M. D. De Smet;B. I. Rubin;A. G. Palestine

396
Citations
Central retinal vein occlusion: a prospective histopathologic study of 29 eyes in 28 cases.

W Richard Green;Chi Chao Chan;Grover M Hutchins;Joseph M Terry

283
Citations

Frequent Co-Authors

Robert B. Nussenblatt National Institutes of Health

Rachel R. Caspi National Institutes of Health

Phyllis B. Silver National Institutes of Health

Emily Y. Chew National Institutes of Health

Igal Gery National Institutes of Health

Barbara Wiggert National Institutes of Health

Mones Abu-Asab National Institutes of Health

Reiko Horai National Eye Institute

Zhengping Zhuang National Institutes of Health

Eric F. Wawrousek National Institutes of Health

External Links

Personal website of Chi-Chao Chan

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