World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
64
Citations
12543
World Ranking
2642
National Ranking
1067

Research.com Recognitions

  • 1951 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Henry J. Kaplan is affiliated with the University of Louisville in the United States and has a significant body of research focusing on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their research contributions include detailed studies within the subfields of Ophthalmology, Immunology, Molecular Biology, Physiology, and Rheumatology.

Kaplan's work often addresses key topics such as ocular diseases and Behçet's syndrome, adenosine and purinergic signaling, systemic lupus erythematosus research, immune cell function and interaction, retinal development and disorders, retinal and optic conditions, and cytomegalovirus and herpesvirus research.

Recent papers authored by Kaplan showcase participation in cutting-edge research across several biomedical areas:

  • Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses, 2021, Science Translational Medicine
  • Short chain fatty acids inhibit endotoxin-induced uveitis and inflammatory responses of retinal astrocytes, 2021, Experimental Eye Research
  • Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia, 2021, PLoS ONE
  • Zeb1 promotes corneal neovascularization by regulation of vascular endothelial cell proliferation, 2020, Communications Biology
  • Sphere-induced reprogramming of RPE cells into dual-potential RPE stem-like cells, 2020, EBioMedicine

Frequent collaborators in Kaplan's research include Deming Sun, Hui Shao, Yongqing Liu, Douglas C. Dean, and Xiaoqin Lu.

Their published research is regularly featured in a variety of scientific journals, with multiple contributions appearing in The Journal of Immunology and Translational Vision Science & Technology. Other notable venues include Cell Reports, Current Research in Immunology, and Biomolecules.

Kaplan's ongoing exploration in the intersection of immunology and ophthalmology informs numerous investigations into inflammatory responses, viral vector engineering, and stem cell biology as it relates to retinal and optic conditions.

Kaplan was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 1951.

Best Publications

  • Role of Complement and Complement Membrane Attack Complex in Laser-Induced Choroidal Neovascularization

    Puran S. Bora;Jeong Hyeon Sohn;Jose M.C. Cruz;Purushottam Jha

  • A Controlled Retrospective Study of Ganciclovir Treatment for Cytomegalovirus Retinopathy: Use of a Standardized System for the Assessment of Disease Outcome

    Gary N. Holland;William C. Buhles;Barbara Mastre;Henry J. Kaplan

  • Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact.

    Shigeo Tamiya;LanHsin Liu;Henry J. Kaplan

  • Differential expression of the complement regulatory proteins in the human eye.

    N S Bora;C L Gobleman;J P Atkinson;J S Pepose

  • Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis.

    J E Fitzgerald;N S Ricalton;A C Meyer;S G West

  • Oxidative stress and the regulation of complement activation in human glaucoma.

    Gülgün Tezel;Xiangjun Yang;Cheng Luo;Angela D. Kain

  • Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells

    Jeong Hyeon Sohn;Puran S. Bora;Hye Jung Suk;Hector Molina

  • The role of glia, mitochondria, and the immune system in glaucoma.

    Gülgün Tezel;Tamir Ben-Hur;Gary E. Gibson;Beth Stevens

  • Immune response to immunization via the anterior chamber of the eye. I. F. lymphocyte-induced immune deviation.

    Unknown

  • Fas ligand (CD95 ligand) controls angiogenesis beneath the retina.

    Henry J. Kaplan;Marc A. Leibole;Tongalp Tezel;Thomas A. Ferguson

  • Generation of an inbred miniature pig model of retinitis pigmentosa.

    Jason W. Ross;Juan P. Fernandez de Castro;Jianguo Zhao;Melissa Samuel

  • Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses.

    Ying Kai Chan;Ying Kai Chan;Sean K. Wang;Colin J. Chu;David A. Copland

  • Behavioral and anatomical abnormalities in a sodium iodate-induced model of retinal pigment epithelium degeneration.

    Volker Enzmann;Barry W. Row;Yasuyuki Yamauchi;Leila Kheirandish

  • Role of epithelial-mesenchymal transition in proliferative vitreoretinopathy.

    Shigeo Tamiya;Henry J. Kaplan

  • Chronic low level complement activation within the eye is controlled by intraocular complement regulatory proteins.

    Jeong-Hyeon Sohn;Henry J. Kaplan;Hye-Jung Suk;Puran S. Bora

  • Human Photoreceptor Transplantation in Retinitis Pigmentosa: A Safety Study

    Henry J. Kaplan;Tongalp H. Tezel;Adam S. Berger;Mitchel L. Wolf

  • A Randomized, Controlled Study of Intravenous Ganciclovir Therapy for Cytomegalovirus Peripheral Retinitis in Patients with AIDS

    Stephen A. Spector;Thomas Weingeist;Richard B. Pollard;Douglas T. Dieterich

  • Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.

    Nalini S. Bora;Sankaranarayanan Kaliappan;Purushottam Jha;Qin Xu

  • Characterization of IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in experimental autoimmune uveitis.

    Yong Peng;Gencheng Han;Hui Shao;Yali Wang

  • Major Role of γδ T Cells in the Generation of IL-17+ Uveitogenic T Cells

    Yan Cui;Hui Shao;Chen Lan;Hong Nian

  • Reengineering of aged Bruch's membrane to enhance retinal pigment epithelium repopulation.

    Tongalp H. Tezel;Lucian V. Del Priore;Henry J. Kaplan

  • Posterior vitreous detachment with dispase.

    Tongalp H. Tezel;Lucian V. Del Priore;Henry J. Kaplan

  • Fate of human retinal pigment epithelial cells seeded onto layers of human Bruch's membrane.

    T H Tezel;H J Kaplan;L V Del Priore

  • PRIMARY RETINAL DETACHMENT REPAIR: Comparison of 1-Year Outcomes of Four Surgical Techniques

    Shlomit Schaal;Mark P Sherman;Charles C Barr;Henry J Kaplan

Frequent Co-Authors

Douglas C. Dean
Douglas C. Dean University of Louisville
Willi K. Born
Willi K. Born University of Colorado Anschutz Medical Campus
Rebecca L. O'Brien
Rebecca L. O'Brien National Jewish Health
Jason W. Ross
Jason W. Ross Iowa State University
Thomas A. Ferguson
Thomas A. Ferguson Washington University in St. Louis
Randall S. Prather
Randall S. Prather University of Missouri
Suzanne T. Ildstad
Suzanne T. Ildstad University of Louisville
John O. Trent
John O. Trent University of Louisville
Jon B. Klein
Jon B. Klein University of Louisville
Scott R. Whittemore
Scott R. Whittemore University of Louisville

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in microbiology, exploring related online degrees can broaden career prospects. Many students find that enrolling in accredited online mph programs easy to get into offers a flexible path to advance in public health, a field closely linked to microbiology.

Career options also extend beyond traditional laboratory roles. For example, becoming a child life specialist combines healthcare and support skills; if you're curious about compensation, learn more about how much do child life specialists make.

It's important to recognize that many online programs cater to diverse learners. Prospective students facing challenges such as a criminal record might find opportunities through college degrees for felons. These accessible programs can help build pathways toward meaningful science careers.

For those interested in healthcare's integrative side, a functional medicine nurse practitioner role may be appealing. Understanding functional medicine np salary can provide insight into the financial rewards of this specialized nursing career.

Best Scientists Citing Henry J. Kaplan

Trending Scientists

Recently Published Articles