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Biology and Biochemistry

D-Index
69
Citations
18904
World Ranking
7318
National Ranking
3352

Overview

Narayan G. Avadhani is affiliated with the University of Pennsylvania in the United States. Their research spans primarily across the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on Molecular Biology, Epidemiology, Physiology, Biochemistry, and Immunology as subfields.

Their scientific work addresses key topics such as mitochondrial function and pathology, peroxisome proliferator-activated receptors, adipose tissue and metabolism, alcohol consumption and health effects, liver disease diagnosis and treatment, eicosanoids and hypertension pharmacology, and T-cell and B-cell immunology.

Avadhani's research output includes publications in multiple reputable venues, among which are:

  • Redox Biology
  • Free Radical Biology and Medicine
  • European Journal of Immunology
  • iScience
  • SSRN Electronic Journal

Some of the recent papers authored or co-authored by Avadhani cover areas related to mitochondrial signaling and dynamics, including:

  • "Mitochondria-targeted paraquat and metformin mediate ROS production to induce multiple pathways of retrograde signaling: A dose-dependent phenomenon" (2020, Redox Biology)
  • "Alcohol-induced CYP2E1, mitochondrial dynamics and retrograde signaling in human hepatic 3D organoids" (2020, Free Radical Biology and Medicine)
  • "YY1 control of mitochondrial-related genes does not account for regulation of immunoglobulin class switch recombination in mice" (2020, European Journal of Immunology)
  • "Dysregulation of RyR Calcium Channel Causes the Onset of Mitochondrial Retrograde Signaling" (2020, iScience)
  • "Dysregulation of RyR Calcium Channel and Impaired Mitochondrial Calcium Uptake Cause the Onset of Mitochondrial Retrograde Signaling" (2020, SSRN Electronic Journal)

The scientist has collaborated frequently with several co-authors, including:

  • Anindya Roy Chowdhury
  • Jacek Zielonka
  • Balaraman Kalyanaraman
  • Rajesh Angireddy
  • Satish Srinivasan

Best Publications

  • Mitochondrial Signaling: The Retrograde Response

    Ronald A Butow;Narayan G Avadhani

  • Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain

    Latha Devi;Vijayendran Raghavendran;Badanavalu M. Prabhu;Narayan G. Avadhani

  • Function of Mitochondrial Stat3 in Cellular Respiration

    Joanna Wegrzyn;Ramesh Potla;Yong Joon Chwae;Naresh B.V. Sepuri

  • Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

    Latha Devi;Badanavalu M. Prabhu;Domenico F. Galati;Narayan G. Avadhani

  • Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells.

    Hindupur K. Anandatheerthavarada;Gopa Biswas;Marie-Anne Robin;Narayan G. Avadhani

  • Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk

    Gopa Biswas;Olugbenga A. Adebanjo;Bruce D. Freedman;Hindupur K. Anandatheerthavarada

  • Cytochrome c oxidase dysfunction in oxidative stress.

    Satish Srinivasan;Narayan G. Avadhani

  • Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection.

    Satish Srinivasan;Manti Guha;Anna Kashina;Narayan G. Avadhani

  • Mitochondria‐to‐nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

    Govindasamy Amuthan;Gopa Biswas;Shi‐Yu Zhang;Andres Klein‐Szanto

  • Blocking FSH induces thermogenic adipose tissue and reduces body fat

    Peng Liu;Yaoting Ji;Yaoting Ji;Tony Yuen;Elizabeth Rendina-Ruedy

  • Mitochondrial stress-induced calcium signaling, phenotypic changes and invasive behavior in human lung carcinoma A549 cells

    Govindasamy Amuthan;Gopa Biswas;Hindupur K Ananadatheerthavarada;Camasamudram Vijayasarathy

  • Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

    Gao Zhang;Dennie T. Frederick;Lawrence Wu;Zhi Wei

  • Preferential attack of mitochondrial DNA by aflatoxin B1 during hepatocarcinogenesis

    BG Niranjan;NK Bhat;NG Avadhani

  • Mitochondria to nucleus stress signaling: a distinctive mechanism of NFκB/Rel activation through calcineurin-mediated inactivation of IκBβ

    Gopa Biswas;Hindupur K. Anandatheerthavarada;Mone Zaidi;Narayan G. Avadhani

  • Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.

    Manti Guha;Narayan G. Avadhani

  • Elevated mitochondrial cytochrome P450 2E1 and glutathione S-transferase A4-4 in streptozotocin-induced diabetic rats: tissue-specific variations and roles in oxidative stress.

    Haider Raza;Subbuswamy K. Prabu;Mari-Anne Robin;Narayan G. Avadhani

  • Protein Kinase A-mediated Phosphorylation Modulates Cytochrome c Oxidase Function and Augments Hypoxia and Myocardial Ischemia-related Injury *

    Subbuswamy K. Prabu;Hindupur K. Anandatheerthavarada;Haider Raza;Satish Srinivasan

  • Doxorubicin Inactivates Myocardial Cytochrome c Oxidase in Rats: Cardioprotection by Mito-Q

    Karunakaran Chandran;Deepika Aggarwal;Raymond Q. Migrino;Joy Joseph

  • Mitochondria-to-nucleus stress signaling in mammalian cells: nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis.

    Gopa Biswas;Manti Guha;Narayan G. Avadhani

  • A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis.

    Adebanjo Oa;Anandatheerthavarada Hk;Koval Ap;Moonga Bs;Moonga Bs

Frequent Co-Authors

Mone Zaidi
Mone Zaidi Icahn School of Medicine at Mount Sinai
Balaraman Kalyanaraman
Balaraman Kalyanaraman Medical College of Wisconsin
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
Andres J. P. Klein-Szanto
Andres J. P. Klein-Szanto Fox Chase Cancer Center
Li Sun
Li Sun Icahn School of Medicine at Mount Sinai
Anil K. Rustgi
Anil K. Rustgi Columbia University
Joy Joseph
Joy Joseph Medical College of Wisconsin
Jacek Zielonka
Jacek Zielonka Medical College of Wisconsin
Michael L. Atchison
Michael L. Atchison University of Pennsylvania
Serge Y. Fuchs
Serge Y. Fuchs University of Pennsylvania

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