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Molecular Biology

D-Index
48
Citations
7953
World Ranking
2692
National Ranking
1307

Overview

Michael L. Atchison is affiliated with the University of Pennsylvania in the United States. Their research primarily spans the fields of Immunology and Microbiology, as well as Biochemistry, Genetics, and Molecular Biology. These areas reflect their focus on cellular and molecular mechanisms in immune system function.

The main subfields of Atchison's research include Immunology, Molecular Biology, Hematology, Epidemiology, and Cell Biology. Their work addresses diverse biological processes and immune system dynamics across these specialized areas.

Key topics in their research encompass T-cell and B-cell Immunology, Immune Cell Function and Interaction, Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, Immunodeficiency and Autoimmune Disorders, Cytomegalovirus and herpesvirus research, and Blood groups and transfusion. These topics indicate a broad but interconnected range of interests focusing on immune regulation, genetic and epigenetic control, and infectious diseases.

Michael L. Atchison has authored several recent papers that contribute to understanding immune regulation and chromatin biology. These include:

  • Altered 3D chromatin structure permits inversional recombination at the IgH locus, 2020, Science Advances
  • YY1 control of mitochondrial-related genes does not account for regulation of immunoglobulin class switch recombination in mice, 2020, European Journal of Immunology
  • YY1 knockout in pro-B cells impairs lineage commitment, enabling unusual hematopoietic lineage plasticity, 2024, Genes & Development
  • Interplay of YY1 and CtBP in the recruitment of PcG complexes to DNA., 2020, The FASEB Journal
  • Multiple lineage-specific epigenetic landscapes at the antigen receptor loci, 2023, Aging Research

Frequent co-authors include Ranjan Sen, Sarmistha Banerjee, Suchita Hodawadekar, Xiang Qiu, and Weiqiang Zhou, suggesting ongoing collaborative efforts in their field.

The scientific outlets where their recent work has been published are diverse and cover notable journals such as Science Advances, European Journal of Immunology, Genes & Development, The FASEB Journal, and Aging Research.

Best Publications

  • PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

    Jm. R. Pongubala;Sujatha Nagulapalli;M. J. Klemsz;S. R. Mckercher

  • Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.

    Kyoungsook Park;Michael L. Atchison

  • Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

    JM Pongubala;C Van Beveren;S Nagulapalli;MJ Klemsz

  • Genes for cytochrome P-450 and their regulation.

    Milton Adesnik;Michael Atchison;Daniel W. Nebert

  • Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X

    Jianle Wang;Camille M. Syrett;Marianne C. Kramer;Arindam Basu

  • Transcription factor YY1 functions as a PcG protein in vivo

    Lakshmi Atchison;Ayesha Ghias;Frank Wilkinson;Nancy Bonini

  • The role of the κ enhancer and its binding factor NF-κB in the developmental regulation of κ gene transcription

    Michael L. Atchison;Robert P. Perry

  • Sumoylation of Oct4 Enhances Its Stability, DNA Binding, and Transactivation

    Fang Wei;Hans R Schöler;Michael L Atchison

  • Polycomb recruitment to DNA in vivo by the YY1 REPO domain

    Frank H. Wilkinson;Kyoungsook Park;Michael L. Atchison

  • Functional antagonism between YY1 and the serum response factor.

    A Gualberto;D LePage;G Pons;S L Mader

  • Characterization of Functional Domains within the Multifunctional Transcription Factor, YY1

    Sarah Bushmeyer;Kyoungsook Park;Michael L. Atchison

  • Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors.

    David Meraro;Sharon Hashmueli;Belly Koren;Aviva Azriel

  • Enhancers: mechanisms of action and cell specificity.

    Michael L. Atchison

  • A cytochrome P-450 multigene family. Characterization of a gene activated by phenobarbital administration.

    M Atchison;M Adesnik

  • Functional characterization of the developmentally controlled immunoglobulin kappa 3' enhancer: regulation by Id, a repressor of helix-loop-helix transcription factors.

    J. M. R. Pongubala;M. L. Atchison

  • Multiple proteins physically interact with PU.1. Transcriptional synergy with NF-IL6 beta (C/EBP delta, CRP3).

    Sujatha Nagulapalli;J. M. R. Pongubala;M. L. Atchison

  • Altered X-chromosome inactivation in T cells may promote sex-biased autoimmune diseases.

    Camille M. Syrett;Bam Paneru;Donavon Sandoval-Heglund;Jianle Wang

  • YY1 DNA binding and PcG recruitment requires CtBP

    Lakshmi Srinivasan;Michael L. Atchison

  • Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: The C-terminus is a principal determinant for nuclear trafficking

    Sandra Marie McNeil;Bo Guo;Janet L. Stein;Jane B. Lian

  • Differential Expression and Distinct Functions of IFN Regulatory Factor 4 and IFN Consensus Sequence Binding Protein in Macrophages

    Sylvia Marecki;Michael L. Atchison;Matthew J. Fenton

Frequent Co-Authors

Robert P. Perry
Robert P. Perry Fox Chase Cancer Center
Milton Adesnik
Milton Adesnik New York University
Ranjan Sen
Ranjan Sen National Institutes of Health
Narayan G. Avadhani
Narayan G. Avadhani University of Pennsylvania
Šárka Pospíšilová
Šárka Pospíšilová Masaryk University
John W. Christman
John W. Christman The Ohio State University
Edward W. Scott
Edward W. Scott University of Florida
John G. Monroe
John G. Monroe University of Pennsylvania
Junwen Wang
Junwen Wang Mayo Clinic
Gerd A. Blobel
Gerd A. Blobel Children's Hospital of Philadelphia

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